Can thyroid cysts become cancerous?

Written by Luo Juan
Endocrinology
Updated on March 20, 2025
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Thyroid cysts can potentially become cancerous. Initially, thyroid cysts may arise from various thyroid diseases such as nodular goiter, Hashimoto's disease, thyroid adenoma, and thyroid follicular cancer, which form through degeneration, liquefaction, and hemorrhage. They are one of the common diseases of the thyroid. In the population, at least 4% of people can feel thyroid nodules larger than one centimeter. Among these nodules, about 5% to 20% are cystic. Statistics show that even benign lesions causing cysts have a 4%-5% chance of becoming cancerous when the diameter of the individual exceeds 4 centimeters. Therefore, thyroid cysts can potentially become cancerous.

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Written by Luo Juan
Endocrinology
57sec home-news-image

Can thyroid cysts become cancerous?

Thyroid cysts can potentially become cancerous. Initially, thyroid cysts may arise from various thyroid diseases such as nodular goiter, Hashimoto's disease, thyroid adenoma, and thyroid follicular cancer, which form through degeneration, liquefaction, and hemorrhage. They are one of the common diseases of the thyroid. In the population, at least 4% of people can feel thyroid nodules larger than one centimeter. Among these nodules, about 5% to 20% are cystic. Statistics show that even benign lesions causing cysts have a 4%-5% chance of becoming cancerous when the diameter of the individual exceeds 4 centimeters. Therefore, thyroid cysts can potentially become cancerous.

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Written by Luo Juan
Endocrinology
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Which department should I go to for a thyroid cyst?

Firstly, we recommend that patients with thyroid cysts should consult the endocrinology department first to assess thyroid function, to determine if there is hypothyroidism, hyperthyroidism, or normal thyroid function. Then, perform a thyroid ultrasound to evaluate the size of the cyst and its relationship with surrounding tissues, etc. Therefore, patients with thyroid cysts should first visit the endocrinology department. If surgical intervention or other further treatments are necessary, then a visit to the breast and thyroid department is needed. However, it is first essential to assess the function and local conditions of the cyst in the endocrinology department before deciding on the next step of treatment.

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Written by Luo Juan
Endocrinology
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Symptoms of thyroid cysts

Regarding the symptoms of thyroid cysts, typically, patients with thyroid cysts do not experience any discomfort in the early stages. Often, a neck mass is incidentally discovered during a physical examination, and usually, there are no systemic clinical symptoms. Some patients may experience slight pain. Of course, if the cyst is large or there is bleeding within the cyst, it may lead to symptoms of compression, such as pain, difficulty swallowing, difficulty breathing, or hoarseness. Additionally, some thyroid cysts can affect thyroid function. For instance, if there is hyperthyroidism, symptoms may include heat intolerance, excessive sweating, and weight loss. Conversely, in long-term cases, patients may experience symptoms of hypothyroidism, such as cold intolerance, fatigue, constipation, and poor appetite.

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Written by Luo Juan
Endocrinology
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How to treat thyroid cystic tumors?

Thyroid cysts refer to fluid-filled sac-like formations or lumps found in the thyroid, generally round in shape, typically painless or only mildly painful, and move up and down with swallowing. Most are solitary nodules, with multiple nodules being less common. Most thyroid cysts do not exhibit obvious clinical symptoms unless the cyst is large or there is bleeding within the cyst, which may lead to symptoms of compression such as pain, difficulty swallowing, difficulty breathing, and hoarseness. Therefore, the treatment of thyroid cysts primarily involves understanding their nature. If a thyroid cyst is malignant, prompt surgical removal should be undertaken; if benign, generally it is sufficient to monitor the cyst through follow-up observations.

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Written by Chen Xie
Endocrinology
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Do thyroid cysts require medication?

Patients with thyroid cysts who have normal thyroid function do not need oral medication treatment; they only need regular monitoring of thyroid function and thyroid ultrasound. However, patients with thyroid cysts accompanied by hyperthyroidism need to be treated for hyperthyroidism, either with oral medication, iodine-131, or surgery. When thyroid cysts are accompanied by hypothyroidism, oral hormone replacement treatment is also required to bring the thyroid function back to normal levels. Therefore, whether patients with thyroid cysts need medication depends on the results of their thyroid function tests.