Can thyroid cysts become cancerous?

Written by Luo Juan
Endocrinology
Updated on March 20, 2025
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Thyroid cysts can potentially become cancerous. Initially, thyroid cysts may arise from various thyroid diseases such as nodular goiter, Hashimoto's disease, thyroid adenoma, and thyroid follicular cancer, which form through degeneration, liquefaction, and hemorrhage. They are one of the common diseases of the thyroid. In the population, at least 4% of people can feel thyroid nodules larger than one centimeter. Among these nodules, about 5% to 20% are cystic. Statistics show that even benign lesions causing cysts have a 4%-5% chance of becoming cancerous when the diameter of the individual exceeds 4 centimeters. Therefore, thyroid cysts can potentially become cancerous.

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Endocrinology
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Foods to avoid with thyroid cysts

For patients with thyroid cysts, it is necessary to first understand the patient's thyroid function, whether it is normal, overactive, or underactive. For patients with thyroid cysts who also have hyperthyroidism, a diet avoiding iodine is still necessary, as excessive iodine intake can significantly affect their hyperthyroid condition, therefore they need to consume iodine-free food. However, for patients with normal thyroid function or those with hypothyroidism, a normal diet is appropriate, and there is no need to avoid iodine. It is also recommended that they avoid smoking and alcohol in their daily life.

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Written by Zhang Li
Endocrinology
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What causes thyroid cysts?

Thyroid cysts currently have no definitive cause identified. Previously, most believed they were possibly related to iodine deficiency, as such deficiency leads to thyroid hyperplasia and an increase in thyroid cysts. However, it was later discovered that in some high-iodine coastal areas, the incidence of thyroid cysts remains high. This suggests that variations in iodine levels, such as switches from low to high iodine or from high to low iodine, can also lead to the occurrence of thyroid cysts. Additionally, it is currently believed that there might be some connection with radiation and the use of mobile phones and computers, but there is no definitive conclusion. Regardless, once thyroid cysts occur, it is important on one hand to eliminate the possibility of malignant features, ruling out thyroid cancer, and on the other hand to ensure thorough thyroid function tests to understand if there are any abnormalities in function and whether treatment is needed.

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Written by Chen Xie
Endocrinology
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How to treat thyroid cysts?

Treatment of thyroid cysts generally does not require special treatment, just regular monitoring of thyroid ultrasound and thyroid function. Thyroid function must be monitored for thyroid cysts. When thyroid function is reduced, hormone replacement therapy is needed. When thyroid function is hyperactive, anti-thyroid treatment is needed. If the patient's thyroid function is normal, only regular monitoring of thyroid ultrasound and thyroid function is required to understand changes in the size of the cyst. However, if the cyst is large enough to cause symptoms such as breathing difficulties or carotid ischemia, surgical treatment is recommended in a timely manner. Currently, radiofrequency treatment is also a new treatment method, which can be considered as an alternative option, but it is not recommended.

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Written by Yang Li
Endocrinology
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Is a grade two thyroid cyst serious?

Thyroid cysts at Grade 2A are generally not very serious. If we consider supporting points for severity in the thyroid, finding one example is considered as first-level evidence, while finding one plus another one counts as second-level evidence. Generally speaking, once it reaches Grade 4A and above, attention needs to be paid as it suggests a malignancy, indicating a higher possibility of malignancy. If it’s below 4A, at Grade 3 and below, it typically suggests a greater likelihood of benign lesions. In such cases, it is recommended to follow up dynamically and definitely conduct an ultrasonic contrast examination.

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Written by Zhao Xin Lan
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Can people with thyroid cysts eat seaweed?

Thyroid cysts generally do not show any symptoms clinically and are mostly benign. They are usually solitary, but occasionally multiple cysts could be present. Currently, the exact cause of thyroid cysts is not completely understood. Some scholars believe that the formation of thyroid cysts is related to iodine deficiency. Others suggest that in areas with a high incidence of thyroid cysts, the iodine content is also relatively high, indicating that both exceptionally low or high levels of iodine could potentially be a cause of thyroid cysts. Seaweed is a food high in iodine. Eating seaweed occasionally should not have a significant impact, but consuming seaweed daily could lead to excessive iodine levels in the body, which is not advisable during periods of thyroid cyst affliction.