What causes systemic lupus erythematosus?

Written by Li Jing
Rheumatology
Updated on September 05, 2024
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Firstly, systemic lupus erythematosus belongs to autoimmune diseases and is a multisystemic autoimmune disorder. It is a chronic disease that cannot be cured. It can only be managed through medication to control the progression of the disease, prevent relapses, delay damage to other organs, and prevent complications. This is the overall principle of treatment. Its cause is currently unclear. It is only related to factors such as environmental pollution, viral infections, genetics, and hormones, according to expert research. However, there is no specific definitive cause identified.

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Written by Li Jing
Rheumatology
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Can systemic lupus erythematosus be cured completely?

Firstly, systemic lupus erythematosus is a chronic autoimmune disease that causes damage to multiple systems. Its occurrence is associated with factors such as genetics, environmental pollution, infections, and hormone levels. As an autoimmune disease, it cannot be completely cured. Treatment involves using medications to control symptoms, delay the onset of complications, reduce disability rates, and improve quality of life. This represents the comprehensive goals of its treatment. The first choice of treatment is corticosteroids. Once diagnosed with systemic lupus erythematosus, it is essential to conduct thorough examinations to assess the activity of the disease and the organs involved. Based on the activity of the disease and the organs affected, the dosage of treatment may vary.

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Written by Li Jing
Rheumatology
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Can systemic lupus erythematosus be cured?

Systemic lupus erythematosus is a multi-system autoimmune disease and a chronic condition with an unclear cause, making it incurable. Treatment primarily involves medication to control the progression of the disease, prevent relapse, and delay the onset of complications in other organs. The comprehensive goal of treatment is to manage these aspects. Additionally, exposure to direct sunlight should be avoided, and women should avoid oral contraceptives, as these can trigger active lupus. Furthermore, it's crucial to avoid consuming figs, bayberries, and other fruits that have been exposed to ultraviolet light over a long period, as they can also induce lupus activity.

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Written by Li Jing
Rheumatology
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Systemic lupus erythematosus is not contagious.

Firstly, systemic lupus erythematosus is an autoimmune disease with an unclear cause. It can affect multiple organs including the heart, lungs, and kidneys. It is classified as an autoimmune disease and not a contagious one, so there is no need to worry about it spreading. However, this condition does have a certain genetic predisposition. For instance, if parents have systemic lupus erythematosus, then their offspring have a relatively higher chance of developing the condition compared to families without a history of the disease. Being an autoimmune disease, it cannot be cured but can only be managed with medications such as corticosteroids to control the progression of the disease. Therefore, during the course of steroid treatment, it is vital to prevent infections. Finally, it is important to emphasize once again that systemic lupus erythematosus is not contagious and does not pose a risk of transmission, so everyone can be reassured.

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Written by Yang Ya Meng
Rheumatology
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What to do if systemic lupus erythematosus causes a fever?

Patients with systemic lupus erythematosus (SLE) who develop a fever first need to discern whether the fever is due to immune-related fever caused by the activity of the disease or an infectious fever due to weakened immunity from long-term use of steroids and immunosuppressants. If the fever is caused by lupus activity, then it is necessary to increase the dosage of corticosteroids in treatment. If the fever is due to an infection, a full course of anti-infection treatment is needed. The anti-infection regimen may even need to include treatments with antibacterial, antifungal, and antiviral medications. (Please follow professional medical advice for medication use, and do not self-medicate.)

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Written by Yang Ya Meng
Rheumatology
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Systemic Lupus Erythematosus Clinical Manifestations

The clinical manifestations of systemic lupus erythematosus are diverse and variable. The primary symptoms involve the bones, joints, and muscles, with joint pain being a common presentation. The second major area affected is the skin and mucous membranes, where the most common symptoms are symmetrical butterfly-shaped erythema and discoid erythema on the face. Some patients experience kidney involvement, primarily presenting as significant proteinuria, hematuria, and cylindrical urine. Pulmonary involvement is also common in some patients, often manifesting as pleurisy. The digestive system can also be affected, typically presenting as abdominal pain. The hematological system is a very common site of involvement in lupus, mainly indicated by routine blood tests showing decreases in white blood cells and platelets.