What to do if systemic lupus erythematosus causes a fever?

Written by Yang Ya Meng

Rheumatology

Updated on March 09, 2025

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Patients with systemic lupus erythematosus (SLE) who develop a fever first need to discern whether the fever is due to immune-related fever caused by the activity of the disease or an infectious fever due to weakened immunity from long-term use of steroids and immunosuppressants. If the fever is caused by lupus activity, then it is necessary to increase the dosage of corticosteroids in treatment. If the fever is due to an infection, a full course of anti-infection treatment is needed. The anti-infection regimen may even need to include treatments with antibacterial, antifungal, and antiviral medications. (Please follow professional medical advice for medication use, and do not self-medicate.)

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Written by Li Jing

Rheumatology

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Can people with systemic lupus erythematosus drink alcohol?

Systemic lupus erythematosus is a chronic systemic autoimmune disease that cannot be cured. It can only be managed with medication to control the progression of the disease, reduce recurrence, delay complications, and decrease mortality and self-harm rates. These are the main treatment objectives. Patients with systemic lupus erythematosus should avoid sun exposure and, for women, the use of oral contraceptives. It is also important to avoid overwork and staying up late. Patients are generally advised to quit smoking and drinking alcohol. Therefore, patients with systemic lupus erythematosus should not consume alcohol, especially during treatment, to avoid adverse reactions with medications.

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Written by Yang Ya Meng

Rheumatology

51sec

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Can systemic lupus erythematosus be cured?

Systemic lupus erythematosus is difficult to cure completely as it is a chronic disease that requires long-term, lifelong medication. The most basic drugs used to treat systemic lupus erythematosus are corticosteroids. Hydroxychloroquine is also a basic treatment for systemic lupus erythematosus, but it is necessary to rule out contraindications such as retinal problems before use. Some patients with systemic lupus erythematosus, if they also have kidney or lung involvement, may need to consider treatment with immunosuppressants after using corticosteroids. Commonly used immunosuppressants include mycophenolate mofetil and cyclophosphamide. (Medication should be taken under the guidance of a physician.)

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Written by Li Jing

Rheumatology

1min 34sec

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Can people with systemic lupus erythematosus have children?

Firstly, systemic lupus erythematosus is an autoimmune disease of unknown etiology, and it can affect multiple organs including the heart, lungs, kidneys, and gastrointestinal tract. Once diagnosed with systemic lupus erythematosus, it is essential to complete routine urine tests, 24-hour urine protein quantification, chest CT, and other related examinations to fully assess the condition and distinguish between mild, moderate, and severe cases. Treatment plans should be formulated based on the assessment of the condition. If it is purely systemic lupus erythematosus without damage to other organs and the condition is stable with reduced maintenance doses of steroids, then pregnancy can be considered. However, during pregnancy, it is crucial to regularly monitor pulmonary arterial hypertension, pulmonary artery pressure, 24-hour urine protein quantification, and kidney function. If complications such as lupus nephritis occur, treatment decisions should be based on the condition. For instance, if there is an increase in creatinine and significant proteinuria, pregnancy is not recommended as it can exacerbate the burden on the kidneys and lead to further deterioration of kidney function.

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Written by Li Jing

Rheumatology

1min 10sec

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What should I do about hair loss from systemic lupus erythematosus?

First, systemic lupus erythematosus is an autoimmune disease characterized by multi-organ and multi-systemic damage, a systemic autoimmune disorder. It cannot be completely cured, but its symptoms can be managed and the progression of the disease can be controlled through medication. The main clinical manifestations include facial rashes, photosensitivity, Raynaud's phenomenon, fever, hair loss, etc. Therefore, in the treatment process of patients with systemic lupus erythematosus, if there is an increase in hair loss, or if other symptoms such as photosensitivity and hair loss occur, it may be considered that the disease is active or recurring. At this time, it is necessary to go to the hospital for comprehensive tests such as blood routine, erythrocyte sedimentation rate (ESR), complement levels, and autoimmune antibodies to assess the condition. If the disease is active or recurring, an adjustment in the dosage of the treatment medications may be necessary.

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Written by Li Jing

Rheumatology

47sec

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What causes systemic lupus erythematosus?

Firstly, systemic lupus erythematosus belongs to autoimmune diseases and is a multisystemic autoimmune disorder. It is a chronic disease that cannot be cured. It can only be managed through medication to control the progression of the disease, prevent relapses, delay damage to other organs, and prevent complications. This is the overall principle of treatment. Its cause is currently unclear. It is only related to factors such as environmental pollution, viral infections, genetics, and hormones, according to expert research. However, there is no specific definitive cause identified.