The clinical manifestations of systemic lupus erythematosus are diverse and variable. The primary symptoms involve the bones, joints, and muscles, with joint pain being a common presentation. The second major area affected is the skin and mucous membranes, where the most common symptoms are symmetrical butterfly-shaped erythema and discoid erythema on the face. Some patients experience kidney involvement, primarily presenting as significant proteinuria, hematuria, and cylindrical urine. Pulmonary involvement is also common in some patients, often manifesting as pleurisy. The digestive system can also be affected, typically presenting as abdominal pain. The hematological system is a very common site of involvement in lupus, mainly indicated by routine blood tests showing decreases in white blood cells and platelets.