Can systemic lupus erythematosus be cured completely?

Written by Li Jing
Rheumatology
Updated on October 28, 2024
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Firstly, systemic lupus erythematosus is a chronic autoimmune disease that causes damage to multiple systems. Its occurrence is associated with factors such as genetics, environmental pollution, infections, and hormone levels. As an autoimmune disease, it cannot be completely cured. Treatment involves using medications to control symptoms, delay the onset of complications, reduce disability rates, and improve quality of life. This represents the comprehensive goals of its treatment. The first choice of treatment is corticosteroids. Once diagnosed with systemic lupus erythematosus, it is essential to conduct thorough examinations to assess the activity of the disease and the organs involved. Based on the activity of the disease and the organs affected, the dosage of treatment may vary.

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Written by Yang Ya Meng
Rheumatology
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Typical skin manifestations of systemic lupus erythematosus

The most typical skin rashes of systemic lupus erythematosus are called butterfly rash and discoid rash. The so-called butterfly rash is a rash on both sides of the nostrils, resembling the wings of a butterfly, and the so-called discoid rash is a circular, disc-shaped rash on the facial area. At the same time, patients with systemic lupus erythematosus may also experience reticular purpura or vasculitic rashes like those of end-finger vasculitis, all of which are typical manifestations of skin rashes in patients with systemic lupus erythematosus.

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Written by Yang Ya Meng
Rheumatology
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What causes systemic lupus erythematosus?

Systemic lupus erythematosus mainly has four major causes: The first is related to the environment. Long-term exposure to sunlight, or living in a humid environment, may trigger the onset of systemic lupus erythematosus. Secondly, there is a certain genetic predisposition to systemic lupus erythematosus. If the parents have systemic lupus erythematosus, the probability of their offspring developing the disease is higher. Thirdly, systemic lupus erythematosus is also related to estrogen, which is why, clinically, lupus is more commonly seen in women of childbearing age and less often in men. Systemic lupus erythematosus is also associated with some specific infections, such as bacterial or viral infections, which may trigger a lupus flare-up.

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Written by Li Jing
Rheumatology
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What causes systemic lupus erythematosus?

Firstly, systemic lupus erythematosus belongs to autoimmune diseases and is a multisystemic autoimmune disorder. It is a chronic disease that cannot be cured. It can only be managed through medication to control the progression of the disease, prevent relapses, delay damage to other organs, and prevent complications. This is the overall principle of treatment. Its cause is currently unclear. It is only related to factors such as environmental pollution, viral infections, genetics, and hormones, according to expert research. However, there is no specific definitive cause identified.

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Written by Li Jing
Rheumatology
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What should I do about hair loss from systemic lupus erythematosus?

First, systemic lupus erythematosus is an autoimmune disease characterized by multi-organ and multi-systemic damage, a systemic autoimmune disorder. It cannot be completely cured, but its symptoms can be managed and the progression of the disease can be controlled through medication. The main clinical manifestations include facial rashes, photosensitivity, Raynaud's phenomenon, fever, hair loss, etc. Therefore, in the treatment process of patients with systemic lupus erythematosus, if there is an increase in hair loss, or if other symptoms such as photosensitivity and hair loss occur, it may be considered that the disease is active or recurring. At this time, it is necessary to go to the hospital for comprehensive tests such as blood routine, erythrocyte sedimentation rate (ESR), complement levels, and autoimmune antibodies to assess the condition. If the disease is active or recurring, an adjustment in the dosage of the treatment medications may be necessary.

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Written by Yang Ya Meng
Rheumatology
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Systemic Lupus Erythematosus Clinical Manifestations

The clinical manifestations of systemic lupus erythematosus are diverse and variable. The primary symptoms involve the bones, joints, and muscles, with joint pain being a common presentation. The second major area affected is the skin and mucous membranes, where the most common symptoms are symmetrical butterfly-shaped erythema and discoid erythema on the face. Some patients experience kidney involvement, primarily presenting as significant proteinuria, hematuria, and cylindrical urine. Pulmonary involvement is also common in some patients, often manifesting as pleurisy. The digestive system can also be affected, typically presenting as abdominal pain. The hematological system is a very common site of involvement in lupus, mainly indicated by routine blood tests showing decreases in white blood cells and platelets.