What medicine is taken for rheumatoid arthritis?

Written by Yang Ya Meng
Rheumatology
Updated on September 24, 2024
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The medication for rheumatoid arthritis mainly falls into three categories,

The first category is the choice of anti-inflammatory and pain relief medications, which mainly includes two types: non-steroidal analgesics and low doses of corticosteroids. If the patient's pain symptoms are mild, non-steroidal analgesics can be opted for. However, if the patient's pain symptoms are more severe, and there is significant liver or kidney damage, or concurrent interstitial lung disease, then the use of low doses of corticosteroids should be considered.

The second and most important category is the choice of immunosuppressants, which include drugs like methotrexate and leflunomide.

The third category is the treatment with biologic agents.

(Medication should be administered under the guidance of a doctor)

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The difference between osteoarthritis and rheumatoid arthritis.

Osteoarthritis is primarily a degenerative joint disease, most commonly occurring in weight-bearing joints and the distal joints of both hands. Therefore, if there is pain in the distal joints of the hands or in joints like the knee, it may be osteoarthritis. Rheumatoid arthritis mainly affects the metacarpophalangeal joints, proximal interphalangeal joints, and both wrists. It is also important to distinguish that in patients with osteoarthritis, inflammation indicators such as sedimentation rate, C-reactive protein, and endocrine factors are usually normal. However, in patients with rheumatoid arthritis, these indicators, including sedimentation rate, C-reactive protein, and rheumatoid factor, are abnormally elevated.

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Rheumatoid arthritis is what's going on?

Rheumatoid arthritis is a chronic systemic disease of unknown etiology characterized primarily by inflammatory synovitis. Its main features are aggressive joint inflammation that symmetrically affects multiple small joints of the hands and feet. It often accompanies involvement of extra-articular organs and a positive rheumatoid factor in serum. It can ultimately lead to joint deformity and loss of function. The onset of the disease may be related to genetic, infectious, and hormonal factors.

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How is rheumatoid arthritis treated?

The treatment of rheumatoid arthritis mainly falls into three categories: The first category includes anti-inflammatory and pain-relief medications, which are further divided into non-steroidal pain-relief drugs and low-dose corticosteroids. For rheumatoid arthritis, the most crucial treatment involves the choice of the second category: slow-acting drugs. Common drugs used in treating the key aspects of rheumatoid arthritis include immunosuppressants such as methotrexate and leflunomide. If the patient does not respond well to the above two conventional treatments, a third option that can be considered is treatment with biological agents. Commonly used biological agents include tumor necrosis factor antagonists. Before using biological agents, it is necessary to strictly rule out hepatitis, tuberculosis, and neoplastic diseases. (Please use medication under the guidance of a doctor)

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Characteristics of rheumatoid arthritis in the hand

The key hand features of rheumatoid arthritis primarily manifest as symmetrical joint swelling and pain in both hands in the early stages. These swollen and painful joints include both wrist joints, bilateral metacarpophalangeal joints, and bilateral proximal interphalangeal joints. Rheumatoid arthritis rarely affects the distal interphalangeal joints of the hands. In the later stages of rheumatoid arthritis, due to the destruction of the hand joints by synovitis, some patients may develop deformities in the hand joints, commonly including ulnar deviation, swan neck deformities, or boutonniere deformities. Some patients may experience significant stiffness leading to limited mobility of the hand joints.

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Does rheumatoid arthritis hurt?

Rheumatoid arthritis damages joints and bones, displaying as symmetrical polyarthritis. It is an autoimmune disease and a chronic condition that cannot be cured but can only be managed through medication to control disease progression. The primary symptoms include symmetrical pain and swelling in multiple joints, particularly in both wrists, therefore it is invariably associated with pain. Some individuals may also experience joint swelling accompanied by morning stiffness, fatigue, low fever, and weight loss. The onset of the disease is generally slow, although a few cases may have a sudden onset. It can also affect specific joints, such as the cervical spine, shoulder joints, and hip joints.