How is rheumatoid arthritis treated?

Written by Liu Li Ning
Rheumatology
Updated on March 17, 2025
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The treatment of rheumatoid arthritis is divided into general treatment and pharmacological treatment.

General treatment mainly involves avoiding overexertion, having a light diet, and not staying up late.

Pharmacological treatment is mainly divided into treatment during the acute flare-up phase and the remission phase. The acute phase focuses on anti-inflammatory and pain relief treatments, with non-steroidal anti-inflammatory drugs (NSAIDs) as the first choice, such as etoricoxib, meloxicam, or celecoxib. If the effect is not satisfactory, low-dose corticosteroid therapy may be combined.

In the remission phase, slow-acting anti-rheumatic drugs are preferred, such as methotrexate, leflunomide, or sulfasalazine. If the slow-acting anti-rheumatic drugs are not effective, biologic agents such as tumor necrosis factor antagonists or JAK inhibitors may be combined.

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Written by Li Jing
Rheumatology
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What medicine is used for rheumatoid arthritis?

First, rheumatoid arthritis is an autoimmune disease and a chronic condition that cannot be cured. The primary goal of treatment is to alleviate symptoms, delay complications, improve quality of life, and reduce disability through conventional drug therapies. Treatment methods include general treatment and medication. General treatment consists of functional exercise and lifestyle considerations, such as avoiding cold water and raw, cold foods, and emphasizing the importance of exercise. Additionally, the first-line drug treatments include nonsteroidal anti-inflammatory drugs and disease-modifying antirheumatic drugs (DMARDs), with traditional DMARDs being the current preferred and anchor treatment option.

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Written by Li Jing
Rheumatology
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Can rheumatoid arthritis be cured?

Rheumatoid arthritis is a chronic autoimmune disease characterized by systemic damage to multiple joints with an unclear cause. Thus, it cannot be cured, meaning it cannot be completely healed. Treatment can only alleviate joint pain and morning stiffness through medication, delay the onset of complications, reduce bone damage, decrease disability rates, and improve quality of life. This is the comprehensive purpose of treatment. Therefore, early diagnosis and standardized treatment of this disease are essential to prevent joint deformities and to maintain quality of life.

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Written by Li Jing
Rheumatology
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What should you pay attention to with rheumatoid arthritis?

Firstly, rheumatoid arthritis is an autoimmune disease. It cannot be cured but can only be managed with medications to control the condition, relieve clinical symptoms, delay the onset of joint deformities, reduce complications, and improve quality of life. These are the main goals of treatment. Therefore, in the treatment process, the following points should be noted: First, do not stop taking medication on your own. After the condition stabilizes, reduce the medication slowly under the guidance of a physician; Second, diagnosis and treatment should be as early as possible to prevent the appearance of joint deformities; Third, during treatment, it's important to periodically recheck blood routine, liver and kidney functions, and electrolytes; Fourth, avoid excessive fatigue. However, one should not be inactive; physical exercise is an important part of the treatment process for rheumatoid arthritis; Fifth, pay attention to keeping warm, avoid getting cold, and avoid the intake of raw and cold foods. These are some important precautions to take.

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Written by Li Jing
Rheumatology
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Rheumatoid arthritis symptoms

Rheumatoid arthritis is categorized as an autoimmune disease and is a chronic autoimmune condition that is destructive to joints. It is primarily characterized by symmetric polyarthritis, with clinical manifestations varying significantly among individuals. Most cases begin gradually, initially presenting with symmetrical pain and swelling in the wrists. This often accompanies morning stiffness, fatigue, low-grade fever, muscle pain, or weight loss. In a minority of cases, the onset is more abrupt, with typical clinical manifestations appearing within a few days, including joint dysfunction, morning stiffness, and joint pain and swelling. Joint deformity is a later manifestation of the disease, indicating that the disease was not well-controlled, leading to joint damage.

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Written by Yang Ya Meng
Rheumatology
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How is rheumatoid arthritis diagnosed?

Rheumatoid arthritis examinations include blood tests and imaging studies. The blood tests include complete blood count, erythrocyte sedimentation rate, rheumatoid factor, C-reactive protein, anti-streptococcal antibodies, ANA, anti-CCP antibodies, and anti-AKA antibodies. Imaging studies involve X-ray examinations of the hand joints. If the patient has significant increases in erythrocyte sedimentation rate and C-reactive protein, positive CCP and AKA antibodies, and the X-rays show bone destruction, then rheumatoid arthritis can be considered as a diagnosis.