Rheumatoid arthritis symptoms

Written by Li Jing
Rheumatology
Updated on September 20, 2024
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Rheumatoid arthritis is categorized as an autoimmune disease and is a chronic autoimmune condition that is destructive to joints. It is primarily characterized by symmetric polyarthritis, with clinical manifestations varying significantly among individuals. Most cases begin gradually, initially presenting with symmetrical pain and swelling in the wrists. This often accompanies morning stiffness, fatigue, low-grade fever, muscle pain, or weight loss. In a minority of cases, the onset is more abrupt, with typical clinical manifestations appearing within a few days, including joint dysfunction, morning stiffness, and joint pain and swelling. Joint deformity is a later manifestation of the disease, indicating that the disease was not well-controlled, leading to joint damage.

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Written by Liu Li Ning
Rheumatology
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How is rheumatoid arthritis treated?

The treatment of rheumatoid arthritis is divided into general treatment and pharmacological treatment. General treatment mainly involves avoiding overexertion, having a light diet, and not staying up late. Pharmacological treatment is mainly divided into treatment during the acute flare-up phase and the remission phase. The acute phase focuses on anti-inflammatory and pain relief treatments, with non-steroidal anti-inflammatory drugs (NSAIDs) as the first choice, such as etoricoxib, meloxicam, or celecoxib. If the effect is not satisfactory, low-dose corticosteroid therapy may be combined. In the remission phase, slow-acting anti-rheumatic drugs are preferred, such as methotrexate, leflunomide, or sulfasalazine. If the slow-acting anti-rheumatic drugs are not effective, biologic agents such as tumor necrosis factor antagonists or JAK inhibitors may be combined.

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Written by Liu Li Ning
Rheumatology
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Rheumatoid arthritis skin manifestations

Rheumatoid arthritis does not have specific skin manifestations. Rheumatoid arthritis is an immune-mediated erosive arthritis, clinically characterized by systemic symmetrical multiple joint swelling and pain, accompanied by morning stiffness, often lasting for more than an hour. Rheumatoid arthritis can affect the proximal interphalangeal joints and middle joints of both hands, as well as both wrists, elbows, shoulders, ankles, knees, and other joints. Some patients may experience involvement of the temporomandibular joint. Rheumatoid arthritis can also have extrarticular manifestations, such as affecting the hematological system, which may result in mild to moderate anemia, or affecting the lungs, which can lead to interstitial pneumonia or pulmonary fibrosis.

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Written by Li Jing
Rheumatology
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Rheumatoid arthritis commonly occurs at what age?

Rheumatoid arthritis is primarily a chronic systemic autoimmune disease characterized by pain in multiple joints throughout the body. The causes of the disease are not yet clear, but it is believed to be related to a combination of genetic, infectious, and environmental factors. The main pathological basis of the disease is synovitis. It commonly occurs in individuals aged between 35 and 50, and is more prevalent in females, with a significantly higher incidence rate in women than in men. Additionally, this disease can lead to disability and loss of work capacity. Therefore, early diagnosis and standard treatment are crucial. Once the condition stabilizes, the dosage should be gradually reduced to maintain the disease in a stable state.

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Written by Yang Ya Meng
Rheumatology
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How is rheumatoid arthritis treated?

The treatment of rheumatoid arthritis mainly falls into three categories: The first category includes anti-inflammatory and pain-relief medications, which are further divided into non-steroidal pain-relief drugs and low-dose corticosteroids. For rheumatoid arthritis, the most crucial treatment involves the choice of the second category: slow-acting drugs. Common drugs used in treating the key aspects of rheumatoid arthritis include immunosuppressants such as methotrexate and leflunomide. If the patient does not respond well to the above two conventional treatments, a third option that can be considered is treatment with biological agents. Commonly used biological agents include tumor necrosis factor antagonists. Before using biological agents, it is necessary to strictly rule out hepatitis, tuberculosis, and neoplastic diseases. (Please use medication under the guidance of a doctor)

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Written by Liu Li Ning
Rheumatology
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How should rheumatoid arthritis be treated?

The treatment of rheumatoid arthritis includes several aspects. First, general treatment: keep a light diet, avoid spicy and stimulant foods, ensure joints are kept warm, and avoid excessive fatigue. Second, medication treatment: during acute flare-ups, non-steroidal anti-inflammatory drugs such as diclofenac sodium or etoricoxib can be used, possibly combined with low doses of corticosteroids. During stable phases, immunosuppressants such as methotrexate or leflunomide are needed. If conventional treatments are ineffective, biological agents like adalimumab or tofacitinib can be combined. Most patients can effectively control their condition after combined treatment. Third, traditional Chinese medicine: alongside Western medicine, Chinese herbal medicine such as total glucosides of paeony or tripterygium wilfordii polyglycoside can be used.