The harms of hyperlipidemia

Written by Li Hui Zhi
Endocrinology
Updated on September 20, 2024
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Hyperlipidemia mainly causes damage to the blood vessels throughout the body, easily leading to arteriosclerosis. In severe cases, plaques may form. This then affects the heart, potentially impacting the coronary arteries, leading to acute coronary syndrome or an acute myocardial infarction. It can also affect the cerebral vessels, possibly causing an acute cerebral infarction. When it affects the lower limb vessels, particularly in combination with diabetes, it can lead to diabetic lower limb vascular changes resulting in vascular occlusion and diabetic foot. Therefore, it is important to treat hyperlipidemia promptly.

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What department should I go to for hyperlipidemia?

Patients with hyperlipidemia should visit the endocrinology department, as hyperlipidemia is a manifestation of lipid metabolism disorder and is classified as a metabolic disease. Therefore, it falls under the purview of the endocrinology department. Moreover, hyperlipidemia is typically divided into secondary and primary types. Many cases of secondary hyperlipidemia are associated with endocrine disorders such as diabetes, hypothyroidism, Cushing's syndrome, and polycystic ovary syndrome, which are primary diseases of the endocrine system that can lead to lipid abnormalities. Therefore, patients with hyperlipidemia should seek treatment in endocrinology to identify the underlying causes of the condition.

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The causes of hyperlipidemia

Regarding the causes of hyperlipidemia, it is generally categorized into primary and secondary types based on the causes. Primary hyperlipidemia is mainly due to genetic defects, such as certain familial hypercholesterolemia and familial mixed dyslipidemia, which are often caused by genetic defects. Secondary hyperlipidemia generally involves some acquired factors, including, for example, high fat content in the diet, which is a common cause of lipid abnormalities. Additionally, obesity can lead to increased plasma cholesterol. Long-term heavy drinking can also increase triglycerides in the blood. Smoking can also cause some drugs, such as estrogen, to raise blood triglycerides. Some glucocorticoids can also increase the synthesis of low-density lipoproteins, and so on. Other causes include diseases such as diabetes, kidney disease, estrogen deficiency, hypothyroidism, systemic lupus erythematosus, glycogen storage diseases, and certain types of malnutrition, which can also lead to secondary lipid abnormalities. Therefore, the causes of hyperlipidemia are multifaceted.

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Written by Zhang Yue Mei
Cardiology
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How is hyperlipidemia formed?

The formation of hyperlipidemia is a very complex physiological process, simply related to the dysregulation of lipid metabolism. Disorders in lipid metabolism are related to some diseases, common ones include diabetes, nephrotic syndrome, liver damage, and gallbladder disease. These diseases can cause increased blood lipids. It is also directly related to an unreasonable dietary structure. Consuming foods that are high in calories and cholesterol, which exceed the body's needs, can lead to increased blood lipids. Examples include animal organs and some high-cholesterol seafood, excessive intake of which can lead to hyperlipidemia.

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Written by Li Hui Zhi
Endocrinology
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How to test for hyperlipidemia?

First, we can take a blood test to check our cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein levels. Second, we can also have a carotid ultrasound to look at the condition of the blood vessels, to see if there is high blood lipid levels, if it has affected the blood vessels, if there is arteriosclerosis, and if plaques have formed. If the diagnosis confirms these conditions, it is advised to control the diet and eat lightly. If diet control is insufficient, then it may be necessary to go to the hospital and choose lipid-lowering medication under the advice of a doctor.

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Written by Li Hui Zhi
Endocrinology
51sec home-news-image

What are the dangers of hyperlipidemia?

If hyperlipidemia is present, it primarily refers to elevated levels of cholesterol, triglycerides, and low-density lipoprotein, though some patients may also have reduced high-density lipoprotein. The main risk of hyperlipidemia is the arterial sclerosis it can cause in blood vessels, which in severe cases can lead to plaque formation. Prolonged arterial sclerosis can cause acute cerebrovascular accidents, cerebral infarction, cerebral hemorrhage, or coronary artery disease of the heart, with severe cases leading to myocardial infarction. Significantly elevated triglycerides may also trigger acute pancreatitis. Therefore, it is essential to control lipid levels and maintain a light diet in cases of hyperlipidemia.