Can allergic purpura be inherited?

Written by Li Jing
Rheumatology
Updated on September 23, 2024
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Allergic purpura is mostly caused by exposure to infections, medications, or foods, leading to skin and mucous membrane ecchymoses, which are essentially petechiae and a manifestation of vasculitis. It falls under autoimmune diseases, not genetic diseases, and thus is not contagious. Bacterial, viral, mycoplasmal, or parasitic infections are the most common causes. Secondarily, medications and foods can also trigger allergic purpura, such as high-protein foods like seafood and milk. Therefore, if there are symptoms like ecchymoses on the lower extremities accompanied by joint pain, or signs of blood in the stool or black stool, it is necessary to complete routine blood tests, erythrocyte sedimentation rate, and autoimmune antibody tests to rule out other autoimmune diseases. During the acute phase, it is advisable to rest in bed, eat a light diet, avoid infection, and use corticosteroids for anti-allergy treatment if necessary.

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Written by Li Jing
Rheumatology
1min 16sec home-news-image

Can allergic purpura be cured?

Allergic purpura mainly occurs in adolescents and children, often in the spring and autumn seasons, and is typically related to bacterial infections, viral infections, and allergies to medications and foods. The most common clinical symptoms include bruises on both lower limbs, bleeding, black stools, joint pain, and abdominal pain. Upon the appearance of bruises on the lower limbs, it is recommended to complete routine blood tests, erythrocyte sedimentation rate, and autoantibody tests to rule out other autoimmune diseases causing skin bruises. During the acute phase, it is necessary to rest in bed, drink plenty of water, and eat a light diet. If there are only simple skin bruises, these may resolve after rest. However, if joint pain, bloody stools, and black stools occur, formal and active treatment is required, as these symptoms will not resolve on their own. Additionally, the presence of blood or protein in urine suggests kidney involvement, indicating that the condition has worsened.

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Written by Li Jing
Rheumatology
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Allergic purpura should go to which department?

Allergic purpura requires a visit to the rheumatology and immunology department. It is common in children and adolescents. This condition cannot be cured and tends to recur frequently. The most common causes of allergic purpura include infections, medications, and food allergies, with infections being the most frequent cause, such as bacterial, viral, tuberculosis, and mycoplasma infections. Once allergic purpura occurs, it is necessary to conduct comprehensive tests to ascertain if there is damage to other organs or complications. If proteinuria occurs, aggressive treatment should be pursued, and a 24-hour urine protein quantification should be completed to determine the level of urinary protein. If necessary, a kidney biopsy may be performed to assess the extent of kidney damage. Bed rest is required until the proteinuria improves. (Medication use should be under the guidance of a doctor.)

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Written by Li Jing
Rheumatology
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How long will allergic purpura take to heal?

Allergic purpura, as the name implies, is subcutaneous hemorrhage caused by allergies and is a type of special vasculitis. This disease is common among adolescents and children aged 5 to 14 and tends to recur without a fundamental cure. Allergic purpura is rare in adults. Once allergic purpura occurs, it is important to classify the types, which can be divided into skin type, abdominal type, renal type, joint type, and mixed type. The purpose of such classifications is mainly to determine the severity of the condition. If it is merely simple skin bruising, antiallergic medication will suffice. However, if it progresses to abdominal and renal types, these two types are the most severe and must be treated formally with attention to bed rest. Mild allergic purpura can be cured, meaning it can resolve on its own. Regarding how long it will take for allergic purpura to improve, this depends on the severity of the condition. Mild cases can improve in about two weeks, but if the kidneys accumulate damage, then it becomes a chronic disease requiring long-term treatment.

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Written by Yang Ya Meng
Rheumatology
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Mild symptoms of allergic purpura

Allergic purpura mainly includes three pathological types. The symptoms of the mild type mainly involve changes in the skin, primarily purpura-like rashes around the lower legs and ankle joints. If there are only skin lesions, it is considered a very mild case of allergic purpura. Additionally, more severe cases may involve kidney impairment, such as the presence of protein in the urine. Some patients primarily experience joint pain, also known as the arthritic type. Another group of patients presents mainly with sudden abdominal pain, primarily known as the abdominal type. Therefore, mild symptoms of allergic purpura might just be typical rashes. As long as there is no involvement of the visceral system, it is considered relatively mild.

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Written by Yang Ya Meng
Rheumatology
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What medicine is taken for allergic purpura?

The medication for allergic purpura should be determined based on the severity of the patient's condition. If the patient only shows symptoms like rashes, the focus should be on reducing the rashes, and medications such as compound glycyrrhizin and desloratadine can be used for their anti-allergic effects. If the main clinical manifestation of allergic purpura is joint pain, some non-steroidal pain relief medications can be added for pain relief. However, if the patient primarily exhibits involvement of internal organs, such as gastrointestinal involvement in allergic purpura starting with abdominal pain, or kidney damage marked by significant proteinuria, then corticosteroids and immunosuppressants should be considered for treatment. (Please use medications under the guidance of a doctor).