Can allergic purpura be cured?

Written by Li Jing
Rheumatology
Updated on September 29, 2024
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Allergic purpura mainly occurs in adolescents and children, often in the spring and autumn seasons, and is typically related to bacterial infections, viral infections, and allergies to medications and foods. The most common clinical symptoms include bruises on both lower limbs, bleeding, black stools, joint pain, and abdominal pain. Upon the appearance of bruises on the lower limbs, it is recommended to complete routine blood tests, erythrocyte sedimentation rate, and autoantibody tests to rule out other autoimmune diseases causing skin bruises. During the acute phase, it is necessary to rest in bed, drink plenty of water, and eat a light diet. If there are only simple skin bruises, these may resolve after rest. However, if joint pain, bloody stools, and black stools occur, formal and active treatment is required, as these symptoms will not resolve on their own. Additionally, the presence of blood or protein in urine suggests kidney involvement, indicating that the condition has worsened.

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Written by Li Jing
Rheumatology
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Is allergic purpura serious?

Firstly, allergic purpura is caused by infections, drugs, or food allergies leading to skin ecchymosis and petechiae; in addition, it can also manifest as joint pain, hematuria, and melena. The presence of protein in a routine urine test along with hematuria or melena often indicates gastrointestinal allergic purpura and renal allergic purpura. The presence of proteinuria suggests kidney involvement, which is the most severe type among various forms of allergic purpura. If it is solely a cutaneous type, no special treatment is needed other than drinking more water and ensuring bed rest to alleviate skin ecchymosis. If proteinuria or hematuria occurs, one must rest in bed until the protein levels improve before resuming activities. Concurrently, corticosteroids and anti-allergy medications should be administered. (Medication should be used under the guidance of a professional doctor.)

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Written by Yang Ya Meng
Rheumatology
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Precursors of recurrent allergic purpura

The precursors of a relapse of allergic purpura typically occur in patients after exposure to cold, strenuous exercise, or allergens, manifesting as purpuric rash on the skin. Additionally, some patients may experience gastrointestinal reactions such as nausea, vomiting, abdominal pain, and diarrhea. More severe cases can present with symptoms of allergic purpura and purpura nephritis, primarily characterized by edema and significant proteinuria indicated in routine urine tests. If patients experience the aforementioned symptoms, it is crucial to be vigilant about the possibility of a relapse of allergic purpura and to seek medical attention promptly to prevent further progression of the disease.

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Written by Pan Wu Shan
Nephrology
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Is allergic purpura nephritis easy to treat?

Allergic purpura nephritis is essentially a kidney complication caused by allergic purpura. The main symptoms are that the patient first presents with scattered purple spots on the lower limbs, known as allergic purpura. Subsequently, routine urine tests reveal hematuria or proteinuria, allowing for a diagnosis of allergic purpura nephritis. It cannot be completely cured. Currently, treatment first requires complete quantification of urine protein and a renal biopsy to confirm whether it is allergic purpura nephritis and its severity. Generally, it involves the use of steroids. Typical treatment involves firstly avoiding allergens, so any substances that cause allergies should not be contacted to prevent triggering allergic purpura, and thus prevent the recurrence of purpura nephritis. Additionally, it involves adhering to a low-salt, low-fat diet, and avoiding catching colds or staying up late.

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Written by Yang Ya Meng
Rheumatology
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Recurrent symptoms of allergic purpura

The clinical manifestations of recurrent allergic purpura primarily include purpuric rashes on the lower limbs. If the patient experiences joint pain, it is also a clinical symptom of recurrent allergic purpura. Some severe cases of allergic purpura may even present with abdominal pain and other gastrointestinal symptoms. Additionally, some patients may exhibit significant amounts of protein in the urine and impaired creatinine levels. This indicates allergic purpura with purpuric nephritis, which is considered severe in the context of allergic purpura. Therefore, if a patient presents with the aforementioned symptoms, the recurrence of allergic purpura should be considered. At this point, further examinations such as blood tests, urine tests, and kidney function tests can be conducted to assess the condition.

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Written by Yang Ya Meng
Rheumatology
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Symptoms of allergic purpura

Allergic purpura, which we generally divide into four types. The first type is the mildest, often primarily characterized by purpuric rash-like skin manifestations. The second type we call allergic purpura arthritis type, where patients, in addition to the typical rash, also experience joint pain symptoms. The third type we refer to as the renal type of allergic purpura, where patients often present primarily with hematuria and proteinuria, and urine tests typically indicate positive urinary protein. The fourth type we call the abdominal type of allergic purpura, where patients suffer from nausea, vomiting, abdominal pain, and diarrhea as their main clinical manifestations.