Early manifestations of gastric cancer

Written by Liu Liang
Oncology
Updated on September 05, 2024
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The early signs of gastric cancer may include nausea, vomiting, or mild acid reflux, which are symptoms similar to those of gastritis, stomach ulcers, or duodenal ulcers. Therefore, initially, these patients may not take their condition seriously, assuming they might just have gastritis or peptic ulcers. These are some of the early manifestations of gastric cancer, and some patients may also experience discomfort and a feeling of fullness after eating.

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How to treat advanced gastric cancer?

The treatment for advanced gastric cancer is primarily chemotherapy, especially for patients with peritoneal or retroperitoneal lymph node metastasis, or distant organ metastasis such as to the liver or lungs. The treatment primarily involves chemotherapy, specifically choosing either multi-drug intravenous combination chemotherapy or oral monotherapy, such as oral chemotherapy with tegafur capsules, or broad-spectrum targeted therapies like apatinib that inhibit angiogenesis. The choice of treatment depends on a comprehensive consideration of the patient's overall condition. If the patient's general condition is particularly poor and the chemotherapy risk is assessed to be high, then the approach for such advanced-stage patients is primarily the best symptomatic supportive treatment to alleviate suffering as much as possible. Therefore, the treatment plan must be determined based on a comprehensive consideration of the specific situation.

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Symptoms of gastric cancer

Symptoms of gastric cancer include nausea, vomiting, acid reflux, pain in the upper abdomen, and a sense of fullness and discomfort, especially after eating, which are some of the early symptoms. As the tumor progresses, symptoms can worsen, including pain, vomiting of blood, and black stools indicating upper gastrointestinal bleeding. If the tumor is near the pylorus, it can cause pyloric obstruction, which manifests as acid reflux followed by vomiting of undigested food from the previous night. In the late stages of gastric cancer, patients may experience fatigue, weight loss, severe cachexia, and anemia. These are symptoms of advanced gastric cancer.

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What are the symptoms of stomach cancer?

Gastric cancer can cause pain in the upper abdomen. If the condition gradually worsens, it can manifest as persistent pain, postprandial fullness and vomiting, belching, and lack of appetite; upper gastrointestinal bleeding, manifesting as vomiting blood, blood in the stool, and black stools; there can also be difficulty swallowing, weight loss and anemia. If bone metastasis occurs, it can manifest as bone pain and pain in the lower back. If a large amount of ascites appears, it can lead to abdominal distension, with shifting dullness detectable on percussion. If liver metastasis occurs, it can manifest as jaundice, and enlargement of the supraclavicular lymph nodes can also occur.

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Oncology
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early symptoms of gastric cancer

The early symptoms of gastric cancer are similar to those of some gastrointestinal diseases such as gastritis, gastric ulcers, or duodenal ulcers. They don't have very specific clinical manifestations. Common symptoms include nausea, vomiting, discomfort or pain in the upper abdomen, and acid reflux-like symptoms, which are early symptoms in patients with gastric cancer. Therefore, when such symptoms appear, it is essential to seek medical attention promptly and undergo a thorough gastroscopy.

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Written by Liu Liang
Oncology
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What is early-stage gastric cancer?

In the early stages of gastric cancer, the tumor is confined to the mucosa or submucosa, regardless of whether there is regional lymph node metastasis or not; this is still classified as early-stage gastric cancer. The treatment for early-stage gastric cancer primarily involves curative surgery, which is the first option unless the patient is of advanced age or has severe underlying diseases that prevent tolerance of surgical treatment. Excluding these cases, surgical treatment is generally the first choice. Furthermore, the outcome of surgical treatment for patients with early-stage gastric cancer is generally quite positive, with a five-year survival rate typically exceeding 80%.