How is gastric cancer treated?

Written by Liu Liang
Oncology
Updated on September 02, 2024
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The treatment methods for gastric cancer include surgery, chemotherapy, and radiotherapy, as well as broad-spectrum targeted therapies against angiogenesis, such as apatinib. Immunotherapy is also an option. However, the specific treatment plan is based on a comprehensive consideration of various factors, including the stage of the cancer and the general condition of the patient. The principle is that for early-stage gastric cancer patients, if the surgeon assesses that surgery is feasible, then radical surgical treatment is primarily used. For advanced-stage patients who are in generally good condition, chemotherapy is the main treatment, combined with a consideration of whether to undergo radiotherapy. For those in very advanced stages, who may not be in good health or those who have had chemotherapy with poor results, anti-angiogenic drugs like apatinib can be chosen as a subsequent treatment.

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Written by Ren Zheng Xin
Gastroenterology
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Is stomach cancer nauseating?

If gastric cancer is complicated by pyloric obstruction, symptoms such as nausea and vomiting may occur. 80% of early gastric cancer does not show obvious symptoms; some people may experience indigestion, as well as anemia, anorexia, and fatigue. If cardia cancer involves the lower part of the esophagus, it can cause difficulty in swallowing, while ulcerative gastric cancer bleeding can lead to vomiting blood or black stools. If gastric cancer metastasizes to the liver, it can cause pain in the upper right abdomen, jaundice, or fever, and if it involves the pancreas, it may cause radiating back pain. If there are long-term symptoms such as indigestion, physical weakness, and loss of appetite, it is advisable to actively visit the department of gastroenterology for a gastroscopy examination.

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Written by Liu Liang
Oncology
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Symptoms of gastric cancer

Symptoms of gastric cancer include nausea, vomiting, acid reflux, pain in the upper abdomen, and a sense of fullness and discomfort, especially after eating, which are some of the early symptoms. As the tumor progresses, symptoms can worsen, including pain, vomiting of blood, and black stools indicating upper gastrointestinal bleeding. If the tumor is near the pylorus, it can cause pyloric obstruction, which manifests as acid reflux followed by vomiting of undigested food from the previous night. In the late stages of gastric cancer, patients may experience fatigue, weight loss, severe cachexia, and anemia. These are symptoms of advanced gastric cancer.

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Written by Liu Liang
Oncology
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How to treat advanced gastric cancer?

The treatment for advanced gastric cancer is primarily chemotherapy, especially for patients with peritoneal or retroperitoneal lymph node metastasis, or distant organ metastasis such as to the liver or lungs. The treatment primarily involves chemotherapy, specifically choosing either multi-drug intravenous combination chemotherapy or oral monotherapy, such as oral chemotherapy with tegafur capsules, or broad-spectrum targeted therapies like apatinib that inhibit angiogenesis. The choice of treatment depends on a comprehensive consideration of the patient's overall condition. If the patient's general condition is particularly poor and the chemotherapy risk is assessed to be high, then the approach for such advanced-stage patients is primarily the best symptomatic supportive treatment to alleviate suffering as much as possible. Therefore, the treatment plan must be determined based on a comprehensive consideration of the specific situation.

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Written by Ren Zheng Xin
Gastroenterology
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Is gastric cancer contagious?

Gastric cancer is a malignant tumor occurring in the epithelial cells of the gastric mucosa. It is non-contagious. Currently, the incidence of gastric cancer is relatively high, primarily due to Helicobacter pylori infection, adverse environmental factors, and dietary irritants. Genetic factors also play a significant role, with 10% of gastric cancer patients having a family history. Those with a family history of gastric cancer have an incidence rate that is 2 to 3 times higher than the general population. Additionally, precancerous lesions can also induce gastric cancer, such as intestinal metaplasia, gastric polyps, residual gastritis, and gastric ulcers. Typical symptoms include indigestion, anemia, lack of appetite, aversion to food, and fatigue. Currently, gastroscopy combined with mucosal biopsy is the most reliable diagnostic method.

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Written by Zhou Zi Hua
Oncology
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Early symptoms of gastric cancer

The symptoms of early gastric cancer are nonspecific and similar to those of chronic gastritis, gastric ulcers, gastroparesis, and other benign diseases, making it difficult to distinguish. Screening data shows that 40%-60% of patients with early gastric cancer are asymptomatic. The symptoms of early gastric cancer primarily include pain or discomfort in the upper abdomen, loss of appetite, fatigue, vomiting, hematemesis, blood in stools, melena, and difficulty swallowing. Discomfort in the upper abdomen is the most common symptom, followed by pain beneath the sternum. Generally, early gastric cancer does not present specific physical signs, though tenderness in the upper abdomen is relatively common, and some patients may exhibit signs of anemia.