Is gastric cancer contagious?

Written by Ren Zheng Xin

Gastroenterology

Updated on January 03, 2025

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Gastric cancer is a malignant tumor occurring in the epithelial cells of the gastric mucosa. It is non-contagious. Currently, the incidence of gastric cancer is relatively high, primarily due to Helicobacter pylori infection, adverse environmental factors, and dietary irritants. Genetic factors also play a significant role, with 10% of gastric cancer patients having a family history. Those with a family history of gastric cancer have an incidence rate that is 2 to 3 times higher than the general population. Additionally, precancerous lesions can also induce gastric cancer, such as intestinal metaplasia, gastric polyps, residual gastritis, and gastric ulcers. Typical symptoms include indigestion, anemia, lack of appetite, aversion to food, and fatigue. Currently, gastroscopy combined with mucosal biopsy is the most reliable diagnostic method.

Other Voices

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Written by Zhou Zi Hua

Oncology

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Early symptoms of gastric cancer

The symptoms of early gastric cancer are nonspecific and similar to those of chronic gastritis, gastric ulcers, gastroparesis, and other benign diseases, making it difficult to distinguish. Screening data shows that 40%-60% of patients with early gastric cancer are asymptomatic. The symptoms of early gastric cancer primarily include pain or discomfort in the upper abdomen, loss of appetite, fatigue, vomiting, hematemesis, blood in stools, melena, and difficulty swallowing. Discomfort in the upper abdomen is the most common symptom, followed by pain beneath the sternum. Generally, early gastric cancer does not present specific physical signs, though tenderness in the upper abdomen is relatively common, and some patients may exhibit signs of anemia.

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Written by Liu Liang

Oncology

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Late-stage symptoms of gastric cancer

The common late-stage symptoms of gastric cancer patients include nausea, vomiting, and even a complete inability to eat. There are also symptoms related to the digestive tract such as pain in the upper abdomen and acid reflux, as well as upper gastrointestinal bleeding, such as vomiting blood and melena which are signs of lower gastrointestinal bleeding. Late-stage gastric cancer patients may also experience organ metastasis, leading to corresponding symptoms. For example, metastasis of gastric cancer to the liver can cause abdominal pain and ascites due to hepatic metastatic tumors. Clinical manifestations caused by such metastatic tumors also include metastasis to retroperitoneal lymph nodes in the abdominal cavity, a common site of spread for gastric cancer. Patients may even show symptoms of intestinal obstruction, such as abdominal pain, bloating, nausea, vomiting, inability to pass stool, or even absence of flatus, which are indicators of intestinal obstruction. Consequently, patients might experience weight loss and deteriorate into a cachectic state, marked by poor nutrition and significant weight loss, which are characteristic symptoms of late-stage patients.

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Written by Liu Liang

Oncology

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How is stomach cancer treated?

The treatment for gastric cancer now includes surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy, among others. The specific treatment plan is formulated based on various factors such as the staging of the cancer, the patient's overall condition, and the presence of any underlying diseases, which are all taken into consideration before deciding on a treatment plan. For patients in the early stages who are generally in good condition, surgical resection can be evaluated and is primarily curative. Post-operative treatment decisions, such as whether to pursue adjuvant radiotherapy or chemotherapy, depend on the pathology results and the presence of high-risk factors for recurrence. For patients in advanced stages who are found to have distant metastases upon diagnosis, treatment is primarily chemotherapy. Additionally, there are broad-spectrum targeted therapies against angiogenesis, such as apatinib, which are suitable for patients with advanced gastric cancer or those who do not respond well to chemotherapy, serving as a secondary or tertiary line of treatment. These are some of the treatment methods for gastric cancer. It is crucial that the use of any medication is conducted under the guidance of a doctor.

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Written by Wang Hui Jie

Gastroenterology

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Early symptoms of gastric cancer

The early symptoms of gastric cancer are not specific or characteristic in clinical presentations, and there are no specific signs either. It can also be said that there are no symptoms or signs at all. Some patients may be diagnosed with gastric cancer after presenting with symptoms of bleeding, such as vomiting blood, blood in stool, or black stools. Therefore, it is recommended for individuals over 40 years old to consider undergoing gastroscopy, especially if they experience discomfort or pain in the upper abdomen, weight loss, or have a history of poor gastric mucosa conditions seen in previous gastroscopies, including atrophy, intestinal metaplasia, or ulcers, as well as a history of testing positive for Helicobacter pylori. Regular follow-up gastroscopies are advised under these circumstances.

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Written by Liu Liang

Oncology

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Does early-stage stomach cancer hurt?

Symptoms of early-stage gastric cancer are generally not very obvious. Some patients may experience subtle symptoms resembling those of gastritis or gastrointestinal ulcers, including non-specific gastrointestinal symptoms such as discomfort and bloating in the upper abdomen, acid reflux, nausea, vomiting, and decreased appetite. In terms of pain, early-stage gastric cancer patients might only experience a sensation of bloating or mild tenderness in the upper abdomen. Severe pain is usually associated with late-stage gastric cancer, occurring when there is extensive abdominal metastasis or tumor progression, and the tumor is large enough to cause significant pain, requiring analgesics for treatment.