Is chemotherapy for gastric cancer torturous?

Written by Liu Liang
Oncology
Updated on February 14, 2025
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The first common side effect of chemotherapy drugs is gastrointestinal reactions, such as nausea, vomiting, decreased appetite, diarrhea, constipation, or bloating, and other such gastrointestinal symptoms. The second is bone marrow suppression, such as decreases in white blood cells and platelets; a decrease in white blood cells can easily lead to infections, and low platelets can lead to a tendency to bleed. There are also liver and kidney damage, numbness of hands and feet in the peripheral nervous system, and clinical symptoms such as fingernail darkening, pigmentation, or hand-foot syndrome caused by fluorouracil. The severity of chemotherapy side effects varies greatly among patients and is related to each patient's general condition, exhibiting significant individual differences. Some patients may experience severe reactions to chemotherapy, while others may have milder reactions. However, during chemotherapy, we provide corresponding symptomatic treatments such as gastric protection, antiemetics, and cardioprotection, among others, to try to minimize the side effects caused by chemotherapy.

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Written by Liu Liang
Oncology
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Late-stage symptoms of gastric cancer

The common late-stage symptoms of gastric cancer patients include nausea, vomiting, and even a complete inability to eat. There are also symptoms related to the digestive tract such as pain in the upper abdomen and acid reflux, as well as upper gastrointestinal bleeding, such as vomiting blood and melena which are signs of lower gastrointestinal bleeding. Late-stage gastric cancer patients may also experience organ metastasis, leading to corresponding symptoms. For example, metastasis of gastric cancer to the liver can cause abdominal pain and ascites due to hepatic metastatic tumors. Clinical manifestations caused by such metastatic tumors also include metastasis to retroperitoneal lymph nodes in the abdominal cavity, a common site of spread for gastric cancer. Patients may even show symptoms of intestinal obstruction, such as abdominal pain, bloating, nausea, vomiting, inability to pass stool, or even absence of flatus, which are indicators of intestinal obstruction. Consequently, patients might experience weight loss and deteriorate into a cachectic state, marked by poor nutrition and significant weight loss, which are characteristic symptoms of late-stage patients.

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Written by Liu Liang
Oncology
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Symptoms of gastric cancer

Symptoms of gastric cancer include nausea, vomiting, acid reflux, pain in the upper abdomen, and a sense of fullness and discomfort, especially after eating, which are some of the early symptoms. As the tumor progresses, symptoms can worsen, including pain, vomiting of blood, and black stools indicating upper gastrointestinal bleeding. If the tumor is near the pylorus, it can cause pyloric obstruction, which manifests as acid reflux followed by vomiting of undigested food from the previous night. In the late stages of gastric cancer, patients may experience fatigue, weight loss, severe cachexia, and anemia. These are symptoms of advanced gastric cancer.

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Written by Zhou Zi Hua
Oncology
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Early symptoms of gastric cancer

The symptoms of early gastric cancer are nonspecific and similar to those of chronic gastritis, gastric ulcers, gastroparesis, and other benign diseases, making it difficult to distinguish. Screening data shows that 40%-60% of patients with early gastric cancer are asymptomatic. The symptoms of early gastric cancer primarily include pain or discomfort in the upper abdomen, loss of appetite, fatigue, vomiting, hematemesis, blood in stools, melena, and difficulty swallowing. Discomfort in the upper abdomen is the most common symptom, followed by pain beneath the sternum. Generally, early gastric cancer does not present specific physical signs, though tenderness in the upper abdomen is relatively common, and some patients may exhibit signs of anemia.

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Written by Ren Zheng Xin
Gastroenterology
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What can stomach cancer patients eat?

Gastric cancer refers to a malignant tumor that occurs in the gastric mucosal epithelium. Special attention should be paid to the diet, appropriately supplementing with multivitamins and consuming more fresh foods, such as fresh green vegetables and fruits. The diet should be diverse to avoid favoring certain foods overly and to ensure the intake of a variety of nutrients. It is also necessary to eat some meat for protein, avoid moldy foods, reduce the consumption of pickled, salted, smoked foods, and those rich in nitrites, and avoid the irritation from strong tea, coffee, and hard liquor. In addition to dietary measures, active treatment for early-stage gastric cancer can include endoscopic mucosal resection, or one may opt for a major gastric resection surgery or radiotherapy, while maintaining a good psychological state and sufficient sleep.

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Written by Liu Liang
Oncology
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Does early-stage stomach cancer hurt?

Symptoms of early-stage gastric cancer are generally not very obvious. Some patients may experience subtle symptoms resembling those of gastritis or gastrointestinal ulcers, including non-specific gastrointestinal symptoms such as discomfort and bloating in the upper abdomen, acid reflux, nausea, vomiting, and decreased appetite. In terms of pain, early-stage gastric cancer patients might only experience a sensation of bloating or mild tenderness in the upper abdomen. Severe pain is usually associated with late-stage gastric cancer, occurring when there is extensive abdominal metastasis or tumor progression, and the tumor is large enough to cause significant pain, requiring analgesics for treatment.