Early symptoms of lymphoma

Written by Yan Chun
Oncology
Updated on June 15, 2025
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Patients with early-stage lymphoma exhibit a variety of symptoms due to the different locations of tumor growth. Many patients initially present with a lump in the neck lymph nodes, which is generally painless and has a tough texture with good mobility. Additionally, some patients with early-stage lymphoma experience enlargement of the mediastinal lymph nodes, leading to respiratory symptoms such as coughing, chest tightness, and shortness of breath. In cases where the lymphoma occurs in the skin, early symptoms might include ulcers and skin peeling or other damaging skin changes. Lymphomas that develop in areas like the gastrointestinal tract or nasopharynx can present early symptoms related to the site of the primary lesion, such as abdominal pain, diarrhea, bloating, or nasopharyngeal bleeding.

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What is lymphoma Ki-67?

Lymphoma Ki67, also known as the proliferation index, is one of the indicators in immunohistochemistry performed after the pathological diagnosis of lymphoma. If this proliferation index is higher, it indicates that the activity of the tumor is stronger, and its proliferation is more active, thus the tumor should be given sufficient attention. Of course, active treatment should be pursued. Therefore, Ki67 reflects the activity of a tumor; if the index is very high, greater than 90%, it sometimes implies that the tumor can grow very rapidly, or not only grows significantly but might also spread to many places.

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Can people with lymphoma eat lamb?

Patients with lymphoma do not have any specific dietary restrictions, unlike traditional Chinese medicine, which refers to certain "heaty" foods that should be avoided. In Western medicine, as long as the diet is nutritionally balanced, including meat, protein, vegetables, and fruits, it fulfills the requirements of a balanced and comprehensive nutrition. The aim is to enhance the patient's immune system. There are no specific foods that are forbidden, so foods like lamb and beef can be consumed by lymphoma patients.

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How many years do people generally live with lymphoma?

Lymphoma is categorized into two main types: Hodgkin lymphoma and non-Hodgkin lymphoma. The specific pathological classification of lymphoma is very complex, involving dozens of types. Differences in the pathological type and stage of the disease can significantly impact the prognosis, including variations in patient sensitivity to chemotherapy or radiotherapy, and consequently, different survival periods. Patients with highly aggressive lymphomas typically have a poorer prognosis, while those with indolent lymphomas usually have a prolonged disease course and slow progression, leading to a longer survival period, sometimes spanning decades. Thus, the survival period varies greatly depending on the pathological type.

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Lymphoma has what manifestations?

The symptoms of lymphoma, simply put, are that some people feel a lump on their neck or in their armpit; it starts as a sudden appearance of a swelling that gets larger over time, sometimes not just one, but multiple lumps clustered together. This is indeed the most common symptom, where one can feel something on their neck, including under the jaw or the chin, noticing suddenly a nodule has formed, whether it's the size of a chicken egg or otherwise. That's one aspect. The second involves systemic symptoms, which primarily include fever, night sweats, and weight loss. These three symptoms are quite common.

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Hodgkin's lymphoma symptoms and signs

Actually, whether it is Hodgkin's lymphoma or non-Hodgkin's lymphoma, the symptoms and signs are quite similar. In terms of symptoms, because lymphoma mainly occurs as a lesion in the lymph nodes, it is characterized by superficial, localized enlargement of the lymph nodes. Common locations include the neck, then the armpits, and the groin—areas where lymph nodes are more prevalent. It manifests as a local swelling; simply put, you might feel a lump or a tumor on your neck, which is the most common symptom. Additionally, there are other systemic symptoms including fever, weight loss, night sweats, and itchy skin, among others. As for the physical signs, it mainly refers to palpable superficial lymph node enlargement upon examination.