Lymphoma has what manifestations?

Written by Peng Li Bo
Oncology
Updated on November 19, 2024
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The symptoms of lymphoma, simply put, are that some people feel a lump on their neck or in their armpit; it starts as a sudden appearance of a swelling that gets larger over time, sometimes not just one, but multiple lumps clustered together. This is indeed the most common symptom, where one can feel something on their neck, including under the jaw or the chin, noticing suddenly a nodule has formed, whether it's the size of a chicken egg or otherwise. That's one aspect. The second involves systemic symptoms, which primarily include fever, night sweats, and weight loss. These three symptoms are quite common.

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Written by Liu Liang
Oncology
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Is lymphoma serious?

The severity of lymphoma relates to its specific pathological type and the stage of discovery among other factors. For instance, some highly aggressive lymphomas grow very rapidly, leading to swift disease progression, resulting in a poorer prognosis and more severe conditions. On the other hand, indolent lymphomas progress slowly, with lymph node growth being particularly sluggish, and the disease course can extend to even decades. Thus, conditions of such indolent lymphomas are relatively milder. The stage of lymphoma at the time of discovery also plays a role; early-stage lymphoma, such as stage I or II, is comparatively less severe. In contrast, patients with later stages, such as stage III or IV, experience more severe conditions. Therefore, the type of pathology and the stage at discovery are all significant factors.

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Written by Zhang Xiao Le
Hematology
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How to rule out lymphoma in children

Lymphoma is a malignant tumor originating from the lymphatic system. The main clinical manifestation is painless lymph node enlargement, which can occur in superficial lymph nodes such as in the neck, armpits, or groin, as well as deeper lymph nodes in the mediastinum or abdominal cavity. In pediatric patients with lymphoma, a significant number also present with abdominal pain, intestinal obstruction, or intussusception, which often indicates intestinal lymphoma. If children exhibit lymph node enlargement or deep lymph node enlargement is discovered through imaging studies, it is necessary to perform a puncture or biopsy and conduct a pathological examination to further confirm whether it is lymphoma.

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Written by Liu Liang
Oncology
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Symptoms of Lymphoma

The symptoms of lymphoma mostly present as painless enlarged superficial lymph nodes, which are common clinical manifestations. Additionally, there may be enlargement of the liver and spleen, with multiple organs throughout the body possibly affected. In advanced stages, patients may experience invasion of the bone marrow. There are also special types of extranodal lymphomas which exhibit specific symptoms. For instance, lymphomas originating in the stomach may present with upper abdominal masses, or symptoms like anemia, weight loss, black stools, and even upper abdominal pain, nausea, and vomiting related to the gastrointestinal tract. If the lymphoma originates in the nasal cavity, known as NK/T-cell lymphoma, symptoms may include tinnitus, nasal congestion, runny nose, and nosebleeds, among others. Some lymphoma patients may also experience fever, generalized weakness, weight loss, collectively referred to as B symptoms.

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Written by Liu Liang
Oncology
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How to check for lymphoma?

Patients with lymphoma generally present with painless enlargement of superficial lymph nodes as their initial symptom, most commonly in areas such as the neck, above the collarbone, and the groin. For diagnostic purposes, it is best, if possible, to conduct a whole-body PADCT scan as this helps in the staging of lymphoma at the initial visit. A definitive diagnosis requires the complete excisional biopsy of the affected superficial lymph node, followed by a pathological examination. An excisional biopsy is a method for confirming the diagnosis of lymphoma.

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Written by Peng Li Bo
Oncology
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Early symptoms of lymphoma

The early symptoms of lymphoma involve the painless enlargement of both superficial and deep lymph nodes, most commonly located in areas such as the neck, armpits, and groin. Of course, lymphoma also presents with systemic symptoms, such as fever, night sweats, weight loss, and skin itching. Since lymphoma commonly occurs in the neck, armpits, and groin, if it develops in other areas, such as the lungs or elsewhere, it may cause respiratory symptoms, including coughing, expectoration, and shortness of breath.