How many years do people generally live with lymphoma?

Written by Liu Liang
Oncology
Updated on June 11, 2025
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Lymphoma is categorized into two main types: Hodgkin lymphoma and non-Hodgkin lymphoma. The specific pathological classification of lymphoma is very complex, involving dozens of types. Differences in the pathological type and stage of the disease can significantly impact the prognosis, including variations in patient sensitivity to chemotherapy or radiotherapy, and consequently, different survival periods. Patients with highly aggressive lymphomas typically have a poorer prognosis, while those with indolent lymphomas usually have a prolonged disease course and slow progression, leading to a longer survival period, sometimes spanning decades. Thus, the survival period varies greatly depending on the pathological type.

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Written by Peng Li Bo
Oncology
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Lymphoma rash symptoms

The rash associated with lymphoma is not much different from common rashes; they are both characterized by red papules. However, lymphoma is not an isolated disease. For instance, in patients, one can feel lumps on the neck or upper clavicle area, but they may also exhibit systemic symptoms such as fever, night sweats, weight loss, fatigue, lack of appetite, anemia, chest pain, and other symptoms because it is a systemic disease. Thus, it may cause these systemic symptoms. The rash can also cause itching of the skin.

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The pattern of fever in lymphoma

Fever symptoms are quite common in patients with lymphoma, which we refer to as B symptoms. The pattern of their fevers is primarily low-grade, occurring more frequently in the afternoon or evening. Unlike ordinary bacterial infections, fevers in these patients do not respond well to anti-inflammatory drugs, but they do respond better to steroid treatment for reducing fever. However, if the lymphoma is not under control, their fever will repeatedly recur. Corresponding cooling treatments can reduce the temperature, but the fever will reoccur repeatedly. Only when the lymphoma and tumor are under control will the fever symptoms start to improve.

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Oncology
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early symptoms of Hodgkin's lymphoma

Malignant lymphoma refers to a type of malignant tumor that originates in the lymph nodes or extranodal organs or tissues. Therefore, Hodgkin's lymphoma is a type of lymphoma. Its early symptoms mainly start with the enlargement of superficial lymph nodes throughout the body, with 90% of Hodgkin's lymphoma patients presenting with enlargement of superficial lymph nodes as an early symptom when they seek medical advice. The most common superficial lymph nodes are those above the collarbone and in the neck, but enlargement can also occur in the axillary and inguinal lymph nodes, which are also some of the more common early clinical manifestations seen in practice.

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Oncology
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Early symptoms of lymphoma

The early symptoms of lymphoma patients are primarily due to its predilection for lymph nodes, with the majority of cases initially presenting with swollen lymph nodes in the neck or collarbone area. These lymph nodes usually enlarge progressively without pain, which is the most common early clinical symptom. However, some specific types of lymphoma, such as nasal NKT lymphoma, present with localized symptoms like nasal congestion, nosebleeds, or a runny nose. There are also lymphomas originating in the stomach, part of the digestive tract, whose symptoms include upper abdominal pain, nausea, or vomiting. Furthermore, some lymphomas originate in the skin, manifesting as skin nodules. Therefore, depending on the site of occurrence, the symptoms can vary, but the enlargement of superficial lymph nodes remains the primary clinical manifestation in most cases.

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Malignant lymphoma chemotherapy regimen

The chemotherapy for malignant lymphoma, I personally don't think is very painful. Actually, lymphoma treatment nowadays not only includes chemotherapy but also targeted therapy and immunotherapy, so it is not very painful. Moreover, generally speaking, the common side effects of chemotherapy include nausea, vomiting, fatigue, poor spirit, constipation, or diarrhea. In clinical practice, these symptoms can be controlled by using antiemetic, hepatoprotective, gastric protective, and cardioprotective drugs. Of course, another common side effect of lymphoma chemotherapy is bone marrow suppression, which can cause a decrease in white blood cells and platelets. However, if there is only a mild decrease, we can restore these levels with oral medication to increase white blood cells or injections to increase white blood cells and platelets. If the suppression is very severe, it could potentially be life-threatening. But strictly speaking, more than 95% of patients can tolerate chemotherapy.