Does hand, foot and mouth disease hurt?

Written by Yan Xin Liang
Pediatrics
Updated on September 26, 2024
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Hand, foot, and mouth disease is caused by an intestinal virus, mainly manifested in children as blisters on the hands, feet, mouth, and buttocks. Some cases may involve fever, while others may have no fever or only mild, low-grade fever. Oral and pharyngeal blisters are quite common, causing oral pain and discomfort. Many children who contract hand, foot, and mouth disease experience a decrease in appetite, which is related to oral and pharyngeal blisters causing pain that affects swallowing and eating.

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Initial symptoms of hand, foot, and mouth disease

Hand, foot, and mouth disease is a contagious disease caused by viral infection, which is common in infants and toddlers, especially those under the age of three. The main symptoms include fever, accompanied by maculopapular rashes or vesicles on the hands, feet, mouth, and buttocks. Some initial symptoms are similar to having a cough, runny nose, headache, mouth pain, or sore throat. Sometimes there may be drooling; consequently, babies might drink less milk, and there can be nausea and vomiting. Additionally, some children may experience nausea and diarrhea along with other gastrointestinal symptoms. Another major sign is the presence of vesicles in the hands, feet, and mouth, or maculopapular rashes on the buttocks.

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Characteristics of hand, foot, and mouth disease rash

Hand, foot, and mouth disease is a rash disease caused by an intestinal virus infection, characterized by scattered maculopapular and vesicular rashes on the hands, feet, buttocks, and other areas. Typically, small vesicles appear on the oral mucosa, or they may already have ruptured into shallow ulcers, primarily located on the tongue, buccal mucosa, palate, and inner lips. Subsequently, rashes appear on the hands and feet, most commonly as maculopapules, which then develop into vesiculopapules about three to seven millimeters in size. The vesicles have a relatively thick covering and are surrounded by reddened skin, predominantly located at the extremities. Sometimes, they may extend to the arms, legs, buttocks, or perineal area. The distribution of the rash is centrifugal, with the number of lesions varying from a few to dozens. Generally, the lesions absorb on their own within two to three days without desquamation, scarring, or pigmentation. The vesicles and ulcers in the mouth mostly heal on their own within a week.

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What should I do about hand, foot, and mouth disease?

Hand, foot, and mouth disease is a common exanthematous infectious disease in children caused by enterovirus infections. Most cases are mild to moderate and can be treated at home with oral medication. Doctors generally prescribe antiviral medications, and if the child's temperature exceeds 38.5 degrees Celsius, antipyretic medications are also required. If there is discomfort in the throat, some medications can be sprayed to relieve local discomfort. For severe cases, such as those caused by EV71 virus infection, it is crucial to be vigilant. This type of infection can lead to symptoms involving the nervous system and may rapidly progress to severe conditions. Therefore, if it is confirmed that the hand, foot, and mouth disease is caused by EV71 infection and the child's condition is serious, hospitalization should be promptly sought. Additionally, for children under three years old, it's important to actively vaccinate against hand, foot, and mouth disease to prevent illness caused by EV71 virus infection.

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Symptoms of hand, foot, and mouth disease

Hand, foot, and mouth disease is a common infectious disease during childhood, characterized by rashes on the hands, feet, and around the mouth as described by its clinical symptoms. Concurrently, with the red rashes, there are symptoms such as fever. In children, vesicles in the throat can cause severe sore throat. These are the common symptoms of hand, foot, and mouth disease. Since hand, foot, and mouth disease is caused by a viral infection, some children may experience myocarditis-like symptoms such as chest tightness, fatigue, and shortness of breath due to the virus affecting the myocardium, or present symptoms of myocardial damage. These are common clinical symptoms of hand, foot, and mouth disease.

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How long should hand, foot, and mouth disease be isolated?

Hand, foot, and mouth disease is an infectious disease caused by enterovirus infection. There are more than 20 common types of enteroviruses, with Coxsackievirus A16 and Enterovirus 71 being the most common. The main clinical symptoms include fever, mouth pain, loss of appetite, and small blisters or ulcers on the hands, feet, and mouth. Most affected children can heal on their own in about a week, so ordinary cases can be isolated for about a week until all the rashes have crusted over and disappeared. However, for severe cases, the isolation period should be extended appropriately, possibly lasting 10-14 days, or even longer.