Late-stage symptoms of hand, foot, and mouth disease

Written by Yan Xin Liang
Pediatrics
Updated on September 02, 2024
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Hand, foot, and mouth disease is an acute infectious disease caused by enterovirus infection. Generally, there are more than twenty types of enteroviruses that cause hand, foot, and mouth disease, but the most common are Coxsackie virus A16 and enterovirus 71. The initial symptoms of hand, foot, and mouth disease are blisters in the hands, feet, and mouth; some cases include fever, while others do not. In later stages, the disease may exhibit recurring fevers, and the blisters on the mouth, hands, feet, and buttocks may burst and crust over. After crusting, the blisters gradually heal, but in some cases, the disease can progress to severe cases. For instance, complications such as encephalitis, brainstem encephalitis, myocarditis can occur, and some cases may develop neurogenic pulmonary edema, pulmonary hemorrhage, and circulatory failure, among others. However, such severe cases are generally rare.

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Written by Li Jiao Yan
Neonatology
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Initial symptoms of hand, foot, and mouth disease

Hand, foot, and mouth disease is a contagious disease caused by viral infection, which is common in infants and toddlers, especially those under the age of three. The main symptoms include fever, accompanied by maculopapular rashes or vesicles on the hands, feet, mouth, and buttocks. Some initial symptoms are similar to having a cough, runny nose, headache, mouth pain, or sore throat. Sometimes there may be drooling; consequently, babies might drink less milk, and there can be nausea and vomiting. Additionally, some children may experience nausea and diarrhea along with other gastrointestinal symptoms. Another major sign is the presence of vesicles in the hands, feet, and mouth, or maculopapular rashes on the buttocks.

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Written by Li Jiao Yan
Neonatology
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Prevention of Hand, Foot, and Mouth Disease

Hand, foot, and mouth disease is a common contagious exanthematous disease in pediatrics, caused by a viral infection with a certain epidemic nature. Its main modes of transmission include respiratory, digestive tracts, and close contact. During the epidemic, usually in the summer and autumn seasons, it is recommended that parents avoid taking children to public places. If a suspected case is found, timely isolation should be carried out, and close contacts should be quarantined for 7-10 days. Additionally, it's important to maintain good personal hygiene, such as washing hands before eating and after using the toilet, and to keep indoor ventilation in the home. If a child has been in contact with an infection or a suspected case of hand, foot, and mouth disease, it is crucial to monitor the child for any discomfort and check their temperature regularly. If the child feels unwell, take them to the hospital for treatment promptly.

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Written by Yao Li Qin
Pediatrics
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Is hand, foot, and mouth disease serious?

Hand, foot, and mouth disease is a contagious viral infection primarily characterized by scattered vesicular or papular rashes on the hands, feet, mouth, and buttocks. It is generally a mild condition, and typical symptoms include fever and rash. It can be treated with oral medications and by taking care of oral and skin hygiene, usually healing quickly. Severe cases caused by the EV71 virus can lead to varying degrees of intracranial pressure. In such serious cases, prompt treatment with mannitol and furosemide to reduce intracranial pressure is necessary; corticosteroids may also be needed if required. For children with severe hypoxia, timely correction of oxygen deficiency is crucial, along with intravenous fluids to maintain stable blood pressure, respiration, heart rate, and microcirculation. (Please consult a professional physician for medication guidance and do not self-medicate.)

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Written by Li Jiao Yan
Neonatology
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How to disinfect hand, foot, and mouth disease?

Hand, foot, and mouth disease is an acute infectious disease caused by a viral infection. It mainly spreads through the respiratory tract, digestive tract, and close contact. Being in contact with a carrier or a child with the disease can result in transmission. It is important to properly handle the infected child's feces and other excretions. Clothes can be soaked in a 3% bleach solution and exposed to sunlight. Keep the room well-ventilated. Other contaminated daily items, such as toys or closely contacted objects like dishware and children's eating utensils, should be disinfected promptly.

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Written by Yan Xin Liang
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Does hand, foot and mouth disease hurt?

Hand, foot, and mouth disease is caused by an intestinal virus, mainly manifested in children as blisters on the hands, feet, mouth, and buttocks. Some cases may involve fever, while others may have no fever or only mild, low-grade fever. Oral and pharyngeal blisters are quite common, causing oral pain and discomfort. Many children who contract hand, foot, and mouth disease experience a decrease in appetite, which is related to oral and pharyngeal blisters causing pain that affects swallowing and eating.