Hand, foot, and mouth disease transmission routes

Written by Yao Li Qin
Pediatrics
Updated on September 03, 2024
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Hand, foot, and mouth disease is caused by an intestinal virus infection, characterized by a rash of scattered maculopapular and vesicular lesions on the hands, feet, mouth, and buttocks. Generally, the prognosis is good. The disease is quite contagious, primarily spreading through the gastrointestinal tract, respiratory tract, and close contact. Therefore, during peak seasons of hand, foot, and mouth disease, children should stay at home and avoid crowded places and playing with children who have the disease. The highest incidence of this disease is among children under three years old, so it is essential to pay attention to the prevention and health care of infants. If a child in kindergarten is found to have the disease, they should rest at home and not return to the kindergarten immediately.

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Written by Yan Xin Liang
Pediatrics
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How many days does hand, foot and mouth disease have a fever?

Hand, foot, and mouth disease is caused by an intestinal virus infection and is characterized by acute fever and vesicles or papules on the hands, feet, mouth, buttocks, and other areas. There are more than 20 types of enteroviruses that cause this disease, with the most common being Enterovirus 71 and Coxsackievirus A16. In typical cases, the fever may last about two to three days, but there are also cases with mild symptoms where no fever appears, or only a low fever occurs, lasting one to two days. In severe cases, the fever may last longer, from three to five days or even more. Therefore, it can only be said that in most cases, the fever in typical cases may last about two to three days.

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Written by Yan Xin Liang
Pediatrics
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Late-stage symptoms of hand, foot, and mouth disease

Hand, foot, and mouth disease is an acute infectious disease caused by enterovirus infection. Generally, there are more than twenty types of enteroviruses that cause hand, foot, and mouth disease, but the most common are Coxsackie virus A16 and enterovirus 71. The initial symptoms of hand, foot, and mouth disease are blisters in the hands, feet, and mouth; some cases include fever, while others do not. In later stages, the disease may exhibit recurring fevers, and the blisters on the mouth, hands, feet, and buttocks may burst and crust over. After crusting, the blisters gradually heal, but in some cases, the disease can progress to severe cases. For instance, complications such as encephalitis, brainstem encephalitis, myocarditis can occur, and some cases may develop neurogenic pulmonary edema, pulmonary hemorrhage, and circulatory failure, among others. However, such severe cases are generally rare.

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Written by Yan Xin Liang
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Is hand, foot and mouth disease itchy?

Hand, foot and mouth disease is an infectious disease caused by enteroviruses. There are more than 20 types of enteroviruses that cause hand, foot and mouth disease, among which Coxsackievirus A16 and Enterovirus 71 are the most common. Its main clinical symptoms include mouth pain, decreased appetite, mild fever, and the appearance of small vesicles or small ulcers on the hands, feet, mouth, and other areas. Most infected children can recover in about a week. The rash of hand, foot and mouth disease typically appears on the hands, feet, buttocks, arms, and legs as maculopapular rash, which can later turn into vesicles. These vesicles are surrounded by an inflammatory red halo and contain relatively little fluid. The rash is not itchy. Thus, the rash of hand, foot and mouth disease is unlike other allergic rashes; it does not cause itching or discomfort.

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Written by Yao Li Qin
Pediatrics
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Initial symptoms of hand, foot, and mouth disease

Hand, foot, and mouth disease is a common pediatric exanthematous disease caused by an enterovirus infection, primarily manifesting on the hands, feet, mouth, and buttocks with scattered vesicular and pustular rashes. The incubation period for hand, foot, and mouth disease generally ranges from three to five days. The initial stage of the illness may include fever and sore mouth, or discomfort in the throat, leading to reluctance in children to eat. Accompanying symptoms might include mild coughing, runny nose, and throat discomfort. During a physical examination, a doctor may observe scattered small vesicles in the mouth mucosa, or shallow ulcers that have already erupted. These are mainly found on the lingual and buccal mucosa, as well as the mucosa on the inner side of the lips and upper palate. Subsequently, rashes appear on the hands and feet, generally starting as maculopapular rashes that slowly turn into vesicular rashes. These rashes are distributed eccentrically and typically resolve on their own within two to three days without scaling, scarring, or pigmentation. The oral vesicles usually heal on their own within a week. Some children with milder cases may only exhibit rashes or vesicular pharyngitis.

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Written by Yao Li Qin
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Does hand, foot, and mouth disease cause fever?

Hand, foot, and mouth disease is a contagious childhood exanthem caused by an intestinal virus infection. The primary symptoms of most hand, foot, and mouth diseases include fever, followed by rashes on the hands, feet, mouth, and buttocks, as well as vesicles in the throat. However, not all children with the disease necessarily experience continuous fever or any fever at all. Some only show symptoms after coming into contact with an infected person, with rashes on the hands, feet, mouth, and buttocks, and vesicles in the throat. In such cases, it is still considered hand, foot, and mouth disease, and fever is not a requisite for diagnosis. Thus, the presence of fever should not be solely relied upon for diagnosing the disease.