Hand, foot, and mouth disease transmission routes

Written by Yao Li Qin
Pediatrics
Updated on September 03, 2024
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Hand, foot, and mouth disease is caused by an intestinal virus infection, characterized by a rash of scattered maculopapular and vesicular lesions on the hands, feet, mouth, and buttocks. Generally, the prognosis is good. The disease is quite contagious, primarily spreading through the gastrointestinal tract, respiratory tract, and close contact. Therefore, during peak seasons of hand, foot, and mouth disease, children should stay at home and avoid crowded places and playing with children who have the disease. The highest incidence of this disease is among children under three years old, so it is essential to pay attention to the prevention and health care of infants. If a child in kindergarten is found to have the disease, they should rest at home and not return to the kindergarten immediately.

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Written by Li Jiao Yan
Neonatology
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Initial symptoms of hand, foot, and mouth disease

Hand, foot, and mouth disease is a contagious disease caused by viral infection, which is common in infants and toddlers, especially those under the age of three. The main symptoms include fever, accompanied by maculopapular rashes or vesicles on the hands, feet, mouth, and buttocks. Some initial symptoms are similar to having a cough, runny nose, headache, mouth pain, or sore throat. Sometimes there may be drooling; consequently, babies might drink less milk, and there can be nausea and vomiting. Additionally, some children may experience nausea and diarrhea along with other gastrointestinal symptoms. Another major sign is the presence of vesicles in the hands, feet, and mouth, or maculopapular rashes on the buttocks.

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Written by Yao Li Qin
Pediatrics
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Characteristics of hand, foot, and mouth disease rash

Hand, foot, and mouth disease is a rash disease caused by an intestinal virus infection, characterized by scattered maculopapular and vesicular rashes on the hands, feet, buttocks, and other areas. Typically, small vesicles appear on the oral mucosa, or they may already have ruptured into shallow ulcers, primarily located on the tongue, buccal mucosa, palate, and inner lips. Subsequently, rashes appear on the hands and feet, most commonly as maculopapules, which then develop into vesiculopapules about three to seven millimeters in size. The vesicles have a relatively thick covering and are surrounded by reddened skin, predominantly located at the extremities. Sometimes, they may extend to the arms, legs, buttocks, or perineal area. The distribution of the rash is centrifugal, with the number of lesions varying from a few to dozens. Generally, the lesions absorb on their own within two to three days without desquamation, scarring, or pigmentation. The vesicles and ulcers in the mouth mostly heal on their own within a week.

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Written by Yan Xin Liang
Pediatrics
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Is hand, foot, and mouth disease contagious?

Hand, foot, and mouth disease is a contagious disease caused by an infection of enteroviruses. There are more than 20 types of enteroviruses that cause the disease, with Coxsackievirus A16 and Enterovirus 71 being the most common. The main clinical manifestations of this disease include blisters on the hands, feet, mouth, and buttocks. Some patients may experience fever, while others may have no fever or only a mild fever. The disease is contagious and primarily transmitted through contact. For example, it can be spread through saliva, droplets, hand-to-mouth contact, and contact with the secretions from the blisters, among other methods.

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Written by Yan Xin Liang
Pediatrics
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Does hand, foot and mouth disease itch?

Hand, foot, and mouth disease is a condition caused by an intestinal virus, primarily characterized by herpes on the hands, feet, oral cavity, and buttocks. Some affected individuals may experience fever, ranging from low to moderate, while others may have high fever, and still others may not have any fever at all. The herpes is neither painful nor itchy, so there is no need for special treatment or handling of the herpes, just symptomatic treatment and timely fever reduction when necessary. For common cases, it is appropriate to orally administer some antiviral medications, and at the same time, take some traditional Chinese medicine that clears heat and detoxifies, while maintaining clean and hygienic skin.

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Written by Yan Xin Liang
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Late-stage symptoms of hand, foot, and mouth disease

Hand, foot, and mouth disease is an acute infectious disease caused by enterovirus infection. Generally, there are more than twenty types of enteroviruses that cause hand, foot, and mouth disease, but the most common are Coxsackie virus A16 and enterovirus 71. The initial symptoms of hand, foot, and mouth disease are blisters in the hands, feet, and mouth; some cases include fever, while others do not. In later stages, the disease may exhibit recurring fevers, and the blisters on the mouth, hands, feet, and buttocks may burst and crust over. After crusting, the blisters gradually heal, but in some cases, the disease can progress to severe cases. For instance, complications such as encephalitis, brainstem encephalitis, myocarditis can occur, and some cases may develop neurogenic pulmonary edema, pulmonary hemorrhage, and circulatory failure, among others. However, such severe cases are generally rare.