Does ovarian cancer hyperthermic intraperitoneal chemotherapy work?

Written by Liu Liang
Oncology
Updated on November 05, 2024
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Patients with ovarian cancer are prone to peritoneal metastasis, so many patients develop ascites during the discovery of the disease or its progression. A large amount of ascites is a common concurrent symptom in patients with ovarian cancer. For patients with significant ascites like this, hyperthermic intraperitoneal chemotherapy (HIPEC) can be performed, which involves infusing chemotherapy drugs into the abdominal cavity and then combining it with thermotherapy. This treatment generally has a decent effect, especially in controlling the spread of cancer cells in the peritoneum and managing ascites.

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Oncology
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Will ovarian cancer recur after complete resection?

After complete removal of ovarian cancer, there is still a possibility of recurrence, especially in patients with high-risk factors. The recurrence rate can be quite high, for example, if there was rupture of the capsule, low differentiation of the pathology, presence of tumor tissue on the surface of the ovary, severe adhesion of the tumor to the surrounding areas, cancer cells found in the abdominal lavage fluid, or presence of vascular tumor thrombus and nerve invasion. Even after total removal, recurrence can still occur.

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How long can one live after ovarian cancer recurrence?

If ovarian cancer patients experience a recurrence after surgery and it is a simple local pelvic recurrence without distant organ metastasis, the treatment method involves evaluating whether another surgical resection can be performed by a gynecologist. However, if there is a recurrence combined with extensive pelvic metastasis, or metastasis to multiple organs, the treatment mainly involves chemotherapy. Therefore, how long a patient can live after ovarian cancer recurrence depends on the severity of the recurrence, the patient's physical condition, and the sensitivity to treatment, among other factors. Thus, it cannot be generalized as there is significant individual variation.

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Written by Liu Liang
Oncology
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How many years can one live with ovarian cancer?

The survival period of ovarian cancer patients is influenced by various factors including the specific stage of the cancer, whether there is residual tumor after surgery, the size of any residual tumor, the pathological type of the cancer, the presence of high-risk factors for recurrence such as vascular tumor thrombus, neural invasion, lymph node metastasis, etc., as well as the patient's age, overall condition, the presence of severe comorbidities, and the patient's response and sensitivity to treatments like radiotherapy and chemotherapy. Survival periods vary due to differences in stages and treatment sensitivities, meaning it cannot be generalized; there is significant individual variation in survival outcomes.

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Written by Liu Liang
Oncology
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What causes ovarian cancer?

The causes of ovarian cancer, and its mechanism of onset, are not yet very clear. Some risk factors that have been relatively well established in relation to the occurrence of ovarian cancer include early menarche, which means starting menstruation at an earlier age, late menopause, and not having a history of pregnancy; these conditions are some of the risk factors for ovarian cancer. Additionally, the occurrence of ovarian cancer is also somewhat related to familial or genetic factors.

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Written by Liu Liang
Oncology
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Is chemotherapy effective after the recurrence of ovarian cancer?

After the recurrence of ovarian cancer, most patients can still benefit from chemotherapy again, as ovarian cancer itself is relatively sensitive to chemotherapy compared to other types of malignant tumors. If the recurrence occurs more than six months after the initial treatment, the same chemotherapy drugs used initially can still be chosen. However, if the recurrence happens within six months, the chemotherapy plan should include different drugs that were not used previously.