How is ovarian cancer diagnosed?

Written by Liu Liang
Oncology
Updated on December 03, 2024
00:00
00:00

Ovarian cancer is discovered through transvaginal ultrasound of the adnexa uteri revealing ovarian tumors, or through imaging studies such as abdominal CT scans or MRIs showing ovarian tumors, combined with tumor markers, particularly the ovarian epithelial cancer tumor marker CA125, which will be significantly elevated. Generally, with these findings, ovarian cancer can typically be clinically diagnosed. Confirmation, however, requires pathological diagnosis, which involves obtaining a biopsy of the tumor. This can be done through a puncture biopsy or through pathological examination after surgical excision to confirm ovarian cancer. Additionally, some patients with ovarian cancer present with substantial ascites at the time of discovery. If cancer cells are found in the abdominal fluid, combined with a significant increase in CA125 and imaging studies showing ovarian tumors, ovarian cancer can also be diagnosed.

Other Voices

doctor image
home-news-image
Written by Yan Chun
Oncology
1min 2sec home-news-image

What are the early symptoms of ovarian cancer?

Patients with ovarian cancer often do not exhibit many symptoms in the early stages, and many do not have obvious symptoms initially. Some patients may experience pelvic pain due to tumor growth early on, primarily located in the bilateral pelvic area, with some experiencing pain that radiates to the perineal area. Some early-stage ovarian cancer patients may experience abnormalities in their menstrual cycle, primarily manifested as irregular menstruation, increased menstrual flow, and the presence of blood clots. Some patients may also experience abnormal vaginal bleeding outside of their menstrual period. In addition, some patients in the early stages may exhibit signs of abnormal hormone secretion. Aside from these, most early-stage ovarian cancer patients do not show obvious symptoms.

doctor image
home-news-image
Written by Liu Liang
Oncology
44sec home-news-image

Can ovarian cancer be detected by transvaginal ultrasound?

Ovarian cancer can generally be detected through a transvaginal ultrasound. During this procedure, we can find cystic or cystic-solid, or a solid mass in the ovaries. If a blood test for tumor markers shows a significant increase in CA125, especially in combination with a large amount of ascites, we must strongly suspect ovarian cancer. In such cases, patients should undergo a tumor biopsy. By taking a biopsy and confirming it pathologically, we can definitively diagnose ovarian cancer. Therefore, most ovarian cancer patients can indeed be detected through a transvaginal ultrasound.

doctor image
home-news-image
Written by Liu Liang
Oncology
40sec home-news-image

Will ovarian cancer recur after complete resection?

After complete removal of ovarian cancer, there is still a possibility of recurrence, especially in patients with high-risk factors. The recurrence rate can be quite high, for example, if there was rupture of the capsule, low differentiation of the pathology, presence of tumor tissue on the surface of the ovary, severe adhesion of the tumor to the surrounding areas, cancer cells found in the abdominal lavage fluid, or presence of vascular tumor thrombus and nerve invasion. Even after total removal, recurrence can still occur.

doctor image
home-news-image
Written by Liu Liang
Oncology
1min 12sec home-news-image

How is ovarian cancer diagnosed?

Ovarian cancer is discovered through transvaginal ultrasound of the adnexa uteri revealing ovarian tumors, or through imaging studies such as abdominal CT scans or MRIs showing ovarian tumors, combined with tumor markers, particularly the ovarian epithelial cancer tumor marker CA125, which will be significantly elevated. Generally, with these findings, ovarian cancer can typically be clinically diagnosed. Confirmation, however, requires pathological diagnosis, which involves obtaining a biopsy of the tumor. This can be done through a puncture biopsy or through pathological examination after surgical excision to confirm ovarian cancer. Additionally, some patients with ovarian cancer present with substantial ascites at the time of discovery. If cancer cells are found in the abdominal fluid, combined with a significant increase in CA125 and imaging studies showing ovarian tumors, ovarian cancer can also be diagnosed.

doctor image
home-news-image
Written by Liu Liang
Oncology
44sec home-news-image

How is ovarian cancer screened?

The most commonly used screening method for ovarian cancer is the B-ultrasound examination of the adnexa uteri. The B-ultrasound can detect ovarian masses and tumors, and when these are found, the possibility of ovarian cancer should be considered, necessitating further examinations for confirmation. Another method involves the tumor marker CA125, which is relatively sensitive and specific for epithelial ovarian cancer. Therefore, for ovarian cancer screening, we can perform a blood test for CA125 in conjunction with a B-ultrasound of the adnexa uteri.