Does ovarian cancer cause abdominal pain every day?

Written by Liu Liang
Oncology
Updated on September 01, 2024
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Patients with ovarian cancer often experience abdominal pain as a common symptom. This is because ovarian cancer can widely implant itself within the pelvic and abdominal cavity, or directly invade the uterus, fallopian tubes, and other tissues and organs within the pelvis, resulting in symptoms of abdominal pain. However, not every patient with ovarian cancer will necessarily exhibit abdominal pain as a clinical symptom, nor is it the case that abdominal pain will occur every day. For instance, some patients with early-stage ovarian cancer may have more concealed clinical presentations and may not experience any specific discomfort. They might discover the disease through physical examinations, gynecological exams, or through ultrasound scans of the uterine adnexa conducted during physical check-ups.

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Oncology
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Is ovarian cancer curable?

Early-stage ovarian cancer patients, meaning those without extensive ascites buildup, and without widespread implant metastasis in the pelvic and abdominal cavity, and without metastasis to distant organs like the liver and lungs. These very early-stage ovarian cancer patients can undergo radical surgery. Postoperative treatment decisions, such as whether postoperative adjuvant radiotherapy or chemotherapy is needed, are based on the postoperative pathological report, which looks for high-risk factors for recurrence such as vascular cancer emboli or neural invasion. Through these treatment approaches, very early-stage ovarian cancer patients can achieve a cure, but this is not absolute. It's not guaranteed that every early-stage ovarian cancer patient can be cured, as there are individual differences. Clinically, if there is no recurrence or metastasis within five years, it is considered a cure.

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What are the symptoms of ovarian cancer?

Some early symptoms of ovarian cancer patients include a lump in the abdomen that can be felt during gynecological examination or by the patients themselves. In advanced ovarian cancer, as the tumor progressively enlarges, there may be symptoms like abdominal pain, bloating, decreased appetite, and weight loss. Moreover, the tumor may compress other organs in the pelvic cavity, causing symptoms such as a feeling of heaviness in the lower abdomen or even constipation. Additionally, many patients with ovarian cancer may develop significant ascites, which can also cause abdominal distension, decreased appetite, and even nausea and vomiting, along with other gastrointestinal symptoms.

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Can ovarian cancer that has spread still be cured?

If ovarian cancer has spread, it is generally considered to be at an advanced stage. The treatment for advanced ovarian cancer primarily involves chemotherapy. Epithelial cancer, the most common type of ovarian cancer, is particularly sensitive to chemotherapy. Most patients benefit from chemotherapy. However, once ovarian cancer has spread and is not caught at a very early stage, even with treatments like chemotherapy, it cannot be cured. The purpose of treatment at this stage is to alleviate the patient's pain and extend their survival, but it cannot be cured.

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ovarian cancer specific drug

Ovarian cancer does not have any specific cure-all treatment. Most ovarian cancers are epithelial ovarian cancers, and there is also ovarian cancer resulting from malignant germ cells, which is a rarer pathology type. For epithelial ovarian cancer, treatment methods include surgery, radiation therapy, chemotherapy, and some targeted therapies, mainly using Bevacizumab, which is a monoclonal antibody that inhibits angiogenesis, and is usually used in combination with chemotherapy drugs. For patients with advanced ovarian cancer, those who are resistant to chemotherapy, or those in poor general health unable to endure chemotherapy, palliative treatments like hormone treatment using progestogens are an option, along with immune therapy being available nowadays. Surgery is primarily for early-stage ovarian cancer patients, where curative surgical resection is possible, or for debulking surgery in patients with advanced ovarian cancer. Chemotherapy is frequently used as it is relatively effective for epithelial ovarian cancer, a type of cancer that is somewhat sensitive to such treatments. The drugs used mainly include taxane combined with platinum-based chemotherapy. For intravenous administration or intraperitoneal delivery—for the latter, mainly for ovarian cancers complicated by extensive ascites—, positioning an abdominal drainage tube and then infusing platinum-based chemotherapy drugs into the abdominal cavity are utilized.

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What tests are done for ovarian cancer screening?

In terms of ovarian cancer screening, we first start with a gynecological examination, followed by a pelvic ultrasound of the adnexa uteri in gynecology. For patients who have given birth, it is best to perform a transvaginal ultrasound of the adnexa uteri. Additionally, blood tests are performed to check the ovarian cancer tumor marker CA125, which is a tumor marker with relatively high specificity and sensitivity, especially for ovarian epithelial cancer. For such types of ovarian cancer, the CA125 level generally shows a significant increase. Therefore, during screening, this tumor marker can be checked in conjunction with a pelvic ultrasound to screen for the disease.