ovarian cancer specific drug

Written by Liu Liang
Oncology
Updated on September 15, 2024
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Ovarian cancer does not have any specific cure-all treatment. Most ovarian cancers are epithelial ovarian cancers, and there is also ovarian cancer resulting from malignant germ cells, which is a rarer pathology type. For epithelial ovarian cancer, treatment methods include surgery, radiation therapy, chemotherapy, and some targeted therapies, mainly using Bevacizumab, which is a monoclonal antibody that inhibits angiogenesis, and is usually used in combination with chemotherapy drugs. For patients with advanced ovarian cancer, those who are resistant to chemotherapy, or those in poor general health unable to endure chemotherapy, palliative treatments like hormone treatment using progestogens are an option, along with immune therapy being available nowadays. Surgery is primarily for early-stage ovarian cancer patients, where curative surgical resection is possible, or for debulking surgery in patients with advanced ovarian cancer. Chemotherapy is frequently used as it is relatively effective for epithelial ovarian cancer, a type of cancer that is somewhat sensitive to such treatments. The drugs used mainly include taxane combined with platinum-based chemotherapy. For intravenous administration or intraperitoneal delivery—for the latter, mainly for ovarian cancers complicated by extensive ascites—, positioning an abdominal drainage tube and then infusing platinum-based chemotherapy drugs into the abdominal cavity are utilized.

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Written by Gong Chun
Oncology
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How is ovarian cancer treated?

Our treatment principle is that once an ovarian tumor is detected, surgical treatment should be performed. First and foremost, we need to confirm the diagnosis. Second, we should clarify the pathological staging of the ovarian cancer to guide the treatment. It's not a single approach; it's a comprehensive treatment plan. For example, if it is early stage and there are no surgical contraindications, we can proceed with surgical treatment. After the surgery, we can provide adjunctive chemotherapy. If surgery is not immediately feasible, we can also provide neoadjuvant therapy to reduce the stage before proceeding with ovarian cancer surgery. Moreover, there is now targeted therapy and immunotherapy for ovarian cancer, so it is a comprehensive treatment plan.

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Written by Liu Liang
Oncology
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Does ovarian cancer cause abdominal pain every day?

Patients with ovarian cancer often experience abdominal pain as a common symptom. This is because ovarian cancer can widely implant itself within the pelvic and abdominal cavity, or directly invade the uterus, fallopian tubes, and other tissues and organs within the pelvis, resulting in symptoms of abdominal pain. However, not every patient with ovarian cancer will necessarily exhibit abdominal pain as a clinical symptom, nor is it the case that abdominal pain will occur every day. For instance, some patients with early-stage ovarian cancer may have more concealed clinical presentations and may not experience any specific discomfort. They might discover the disease through physical examinations, gynecological exams, or through ultrasound scans of the uterine adnexa conducted during physical check-ups.

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Written by Liu Liang
Oncology
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How long can one live after ovarian cancer recurrence?

If ovarian cancer patients experience a recurrence after surgery and it is a simple local pelvic recurrence without distant organ metastasis, the treatment method involves evaluating whether another surgical resection can be performed by a gynecologist. However, if there is a recurrence combined with extensive pelvic metastasis, or metastasis to multiple organs, the treatment mainly involves chemotherapy. Therefore, how long a patient can live after ovarian cancer recurrence depends on the severity of the recurrence, the patient's physical condition, and the sensitivity to treatment, among other factors. Thus, it cannot be generalized as there is significant individual variation.

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Written by Wu Xia
Oncology
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What to eat for difficulty in defecation due to ovarian cancer?

If the difficulty in defecation is due to ovarian cancer involving the rectum or other parts, we can apply anti-tumor treatments such as surgery and chemotherapy to control the condition and facilitate defecation. If the issue is caused by painkillers or the patient's inherent constipation, diet is crucial. The diet must include an adequate amount of fiber, more vegetables, and fruits. Avoid overly refined staple foods and include more whole grains. Drinking a glass of saltwater or honey water on an empty stomach in the morning, combined with appropriate waist and abdominal massage, can enhance the effect of facilitating bowel movements. If these measures are still ineffective, laxatives such as sodium docupate or lactulose may be used, along with some traditional Chinese medicines.

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Written by Gong Chun
Oncology
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What are the symptoms of ovarian cancer?

In the early stages, ovarian cancer often doesn't show many symptoms and can be detected during gynecological examinations. However, as it progresses, symptoms such as abdominal bloating, lumps in the abdomen, and ascites may occur. The severity of these symptoms depends on the size and location of the tumor, the extent to which it has invaded nearby organs, the histological type of the tumor, and whether the malignant tumor, ovarian cancer, has metastasized to other areas or is accompanied by other complications.