Will ovarian cancer recur after complete resection?

Written by Liu Liang
Oncology
Updated on April 04, 2025
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After complete removal of ovarian cancer, there is still a possibility of recurrence, especially in patients with high-risk factors. The recurrence rate can be quite high, for example, if there was rupture of the capsule, low differentiation of the pathology, presence of tumor tissue on the surface of the ovary, severe adhesion of the tumor to the surrounding areas, cancer cells found in the abdominal lavage fluid, or presence of vascular tumor thrombus and nerve invasion. Even after total removal, recurrence can still occur.

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What causes ovarian cancer?

The causes of ovarian cancer, and its mechanism of onset, are not yet very clear. Some risk factors that have been relatively well established in relation to the occurrence of ovarian cancer include early menarche, which means starting menstruation at an earlier age, late menopause, and not having a history of pregnancy; these conditions are some of the risk factors for ovarian cancer. Additionally, the occurrence of ovarian cancer is also somewhat related to familial or genetic factors.

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How many years can one live with ovarian cancer?

The survival period of ovarian cancer patients is influenced by various factors including the specific stage of the cancer, whether there is residual tumor after surgery, the size of any residual tumor, the pathological type of the cancer, the presence of high-risk factors for recurrence such as vascular tumor thrombus, neural invasion, lymph node metastasis, etc., as well as the patient's age, overall condition, the presence of severe comorbidities, and the patient's response and sensitivity to treatments like radiotherapy and chemotherapy. Survival periods vary due to differences in stages and treatment sensitivities, meaning it cannot be generalized; there is significant individual variation in survival outcomes.

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Symptoms of ovarian cancer brain metastasis

Patients with ovarian cancer experiencing brain metastases are relatively uncommon in clinical settings. The primary symptom of brain metastasis is intracranial hypertension, which includes severe headaches, dizziness, nausea, and vomiting, including projectile vomiting during meals — all symptoms of increased intracranial pressure. Additionally, if there is significant brain swelling, the patient may experience weakness in the limbs on the opposite side of the body, similar to symptoms of paralysis seen in stroke patients. Furthermore, if the brain metastasis leads to the formation of a brain herniation, the patient may experience symptoms such as coma.

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Early treatment methods for ovarian cancer

The treatment methods for early-stage ovarian cancer should first and foremost include a clear diagnosis and staging. If the staging indicates an early stage, then surgical treatment can be applied. There are many surgical options available, such as cytoreductive surgery, interval debulking surgery, second-look laparotomy, and direct tumor cell reduction surgery. After the surgery, adjuvant chemotherapy can be administered for treatment.

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Does ovarian cancer hyperthermic intraperitoneal chemotherapy work?

Patients with ovarian cancer are prone to peritoneal metastasis, so many patients develop ascites during the discovery of the disease or its progression. A large amount of ascites is a common concurrent symptom in patients with ovarian cancer. For patients with significant ascites like this, hyperthermic intraperitoneal chemotherapy (HIPEC) can be performed, which involves infusing chemotherapy drugs into the abdominal cavity and then combining it with thermotherapy. This treatment generally has a decent effect, especially in controlling the spread of cancer cells in the peritoneum and managing ascites.