Rickets is caused by a deficiency of what element?

Written by Li Jiao Yan
Neonatology
Updated on March 14, 2025
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Rickets is a systemic chronic nutritional disease caused by vitamin D deficiency leading to disturbances in calcium and phosphorus metabolism, which results in abnormal bone development. The main cause is a lack of vitamin D, generally related to feeding methods, the addition of cod liver oil, living environment, outdoor activity time, repeated respiratory infections, calcium deficiency during pregnancy, and the season of birth. It is generally recommended to routinely supplement vitamin D and cod liver oil after birth, have regular follow-ups, engage in appropriate outdoor activities, and during pregnancy, it is important to supplement with adequate calcium and vitamin D. Additionally, attention should be paid to children who have repeated respiratory and gastrointestinal diseases, as these can also affect the absorption of vitamin D and calcium and phosphorus. Thus, it is vital to actively prevent other diseases that may affect the absorption of vitamin D and to treat illnesses proactively when they occur.

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Written by Li Jiao Yan
Neonatology
1min 31sec home-news-image

Can rickets be cured?

Can rickets be cured? Rickets, also known as nutritional vitamin D deficiency rickets, is primarily caused by insufficient levels of vitamin D in the body leading to disorders in calcium and phosphorus metabolism. It is a chronic nutritional disease characterized by skeletal lesions. Typically, it manifests as flawed mineralization of long bones and bone tissue at the growth plates. Vitamin D deficiency rickets is a self-limiting disease that can generally be cured if children have sufficient outdoor activities and adequate exposure to sunlight. Adequate sunlight exposure and physiological doses of vitamin D can treat rickets. Therefore, it is usually recommended that children supplement with 400 units of vitamin D starting about two weeks after birth to prevent and treat rickets. However, if the child is in a later stage and shows obvious skeletal deformities, corrective treatment may be necessary. In severe cases of rickets where intracranial lesions occur, it might affect the child's vital signs and, in serious cases, could even lead to the child's death. Therefore, it is advised that children get plenty of sunlight, routinely supplement with vitamin D, and have regular pediatric check-ups to assess their condition.

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Written by Li Jiao Yan
Neonatology
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Early clinical manifestations of rickets

Early Symptoms of Rickets: Rickets is a chronic nutritional disease caused by a deficiency in Vitamin D, leading to disordered calcium and phosphorus metabolism and resulting in abnormal skeletal development. It primarily affects infants, especially those under six months old, with the highest occurrence in infants under three months. The general symptoms include heightened neural excitability, such as fussiness, easy irritability, sudden bouts of crying, or being so sensitive that they cry when touched. Other symptoms include excessive sweating and frequent head shaking, though these are not specific indicators of rickets. Diagnosis mainly relies on biochemical markers and Vitamin D levels, like decreased blood calcium and phosphorus levels, elevated parathyroid hormone levels, and reduced 25-hydroxy-D3. X-ray images of bones might appear normal.

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Written by Li Jiao Yan
Neonatology
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Is rickets easy to treat?

Rickets is primarily a nutritional disease caused by insufficient levels of vitamin D leading to disturbances in calcium and phosphate metabolism, resulting in abnormal bone development. The most common type is nutritional vitamin D-deficiency rickets. This type of disease is self-limiting and thus relatively easy to treat. It requires early detection and proactive intervention. Early measures include encouraging children to engage in outdoor activities and supplementing with appropriate doses of vitamin D, which can effectively treat rickets. However, there are also special causes of vitamin D deficiency such as significant anomalies in liver or kidney function and certain genetic diseases that severely impair vitamin D absorption. When vitamin D treatment is ineffective, it may be due to other special causes. Treatment of rickets under these circumstances can be more challenging, and genetic diseases may respond poorly to treatment.

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Written by Yan Xin Liang
Pediatrics
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Does rickets have a hereditary component?

Rickets, also known as vitamin D deficiency rickets, is primarily a chronic nutritional disease characterized by skeletal lesions, caused by insufficient vitamin D in infants, children, or adolescents, which leads to disturbances in calcium and phosphorus metabolism. The main feature of this disease is the incomplete calcification of the growth plates and bone tissue in the growing long bones, due to the lack of vitamin D causing incomplete calcification of mature bones. This disease is most common in children under two years old. Its causes may be related to insufficient intake of vitamin D or insufficient sunlight exposure, as well as rapid growth. Additionally, other diseases may influence its development. Therefore, this disease is generally not closely related to genetics.

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Written by Yao Li Qin
Pediatrics
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Can rickets be vaccinated against?

Children with rickets can be vaccinated, as rickets is not listed among the contraindications for vaccination. Rickets is a disease caused by a deficiency of vitamin D, a nutritional issue. Once diagnosed with rickets, it is essential to treat the child promptly by supplementing vitamin D. Generally, if treated early during infancy, rickets can be cured. To prevent rickets, all children should supplement with the physiological requirement of vitamin D from birth, engage in outdoor activities, and get ample sunlight to thoroughly prevent the occurrence of rickets. Rickets does not affect the administration of vaccines, nor does vaccination exacerbate the symptoms of rickets. Therefore, it is clear that children with rickets can be vaccinated.