Ovarian cancer


Can ovarian cancer be cured?
Whether ovarian cancer can be cured depends on the clinical stage of the patient, as well as the patient's sensitivity to treatment, among other factors. If it is a case of early-stage ovarian cancer, curative surgery can be performed. After surgery, based on the pathology, it can be decided whether postoperative adjuvant radiotherapy or chemotherapy is necessary. Patients with early-stage ovarian cancer who undergo surgery or postoperative adjuvant radiotherapy and chemotherapy may have hope for a cure. However, if the cancer is discovered at a late stage where it has spread extensively, such as widespread metastasis to the pelvic area, or even to distant organs like the lungs or liver, then the treatment for these patients is primarily chemotherapy. A cure is not achievable; the treatment aims to alleviate symptoms and prolong the patient's life. Thus, for patients with late-stage ovarian cancer, treatment cannot achieve a curative purpose.


How is ovarian cancer diagnosed?
Ultrasound or CT scans detecting ovarian masses, in combination with biopsy or cytological examination that identify cancer cells, can diagnose ovarian cancer. A common method of biopsy includes ultrasound-guided procedures or transvaginal cul-de-sac puncture biopsy of ovarian masses, enabling clear pathological confirmation. Additionally, exploratory laparotomy or early radical surgery for ovarian cancer patients can yield a postoperative pathological diagnosis of ovarian cancer. Moreover, the presence of ascites is a common symptom in ovarian cancer patients; finding cancer cells, especially adenocarcinoma, in ascites, coupled with significantly elevated tumor marker CA125, or ultrasound or CT imagery revealing ovarian masses, can also diagnose ovarian cancer.


Ovarian Cancer Screening Methods
The methods for diagnosing ovarian cancer include imaging studies, such as ultrasonography of the adnexa of the uterus, abdominal CT, or MRI, which can detect ovarian tumors. The next step is to perform a blood test for the tumor marker CA125, which is a relatively specific and sensitive marker for epithelial ovarian cancer; in clinical practice, CA125 levels are generally significantly elevated in patients with ovarian cancer. Additionally, many patients with ovarian cancer, especially those in advanced stages, often develop significant ascites. We can perform abdominal paracentesis to drain the fluid and test the ascites for cancer cells. If cancer cells are found in the ascites and imaging studies reveal an ovarian mass, ovarian cancer can be diagnosed. Furthermore, chest CT and other tests are included to comprehensively assess the staging of the patient.


How is ovarian cancer treated?
Our treatment principle is that once an ovarian tumor is detected, surgical treatment should be performed. First and foremost, we need to confirm the diagnosis. Second, we should clarify the pathological staging of the ovarian cancer to guide the treatment. It's not a single approach; it's a comprehensive treatment plan. For example, if it is early stage and there are no surgical contraindications, we can proceed with surgical treatment. After the surgery, we can provide adjunctive chemotherapy. If surgery is not immediately feasible, we can also provide neoadjuvant therapy to reduce the stage before proceeding with ovarian cancer surgery. Moreover, there is now targeted therapy and immunotherapy for ovarian cancer, so it is a comprehensive treatment plan.


Symptoms of ovarian cancer
Ovarian cancer patients, especially those in the early stages, typically have inconspicuous symptoms, possibly without any noticeable discomfort. The disease is often discovered during gynecological examinations through the detection of abdominal masses. In advanced-stage patients, as the abdominal mass progressively enlarges, symptoms may include abdominal pain, lower abdominal bloating, and pelvic pressure symptoms due to compression of nearby organs. There may be partial intestinal obstruction, presenting as nausea, vomiting, abdominal pain, and inability to pass stool or gas. Another symptom is ascites, characterized by progressive enlargement and bloating of the abdomen. Ascites is a common clinical manifestation in ovarian cancer patients, and a significant portion of patients are diagnosed with ovarian cancer after presenting with ascites as the initial symptom.


What are the symptoms of ovarian cancer?
Ovarian cancer often does not present symptoms in its early stages and can be detected during gynecological examinations. Secondly, as the tumor grows, it can cause abdominal swelling and discomfort, and abdominal masses may be felt during examinations. Ascites may also develop. The severity of these symptoms depends on the size and location of the tumor, the nearby organs it invades, and the histological type of the tumor. Thirdly, if the tumor infiltrates or compresses surrounding tissues, it can also lead to abdominal pain, back pain, and pain in the lower extremities. If it compresses the pelvic veins, swelling in the lower limbs may occur. If the tumor is functional, it can produce symptoms related to excess estrogen or androgen. In its later stages, the condition may manifest as cachexia and severe anemia, among other signs of a severe illness state.


Early treatment methods for ovarian cancer
The treatment methods for early-stage ovarian cancer should first and foremost include a clear diagnosis and staging. If the staging indicates an early stage, then surgical treatment can be applied. There are many surgical options available, such as cytoreductive surgery, interval debulking surgery, second-look laparotomy, and direct tumor cell reduction surgery. After the surgery, adjuvant chemotherapy can be administered for treatment.


Can ovarian cancer be treated?
Ovarian cancer is certainly treatable. Its treatment methods include surgery, radiotherapy, and chemotherapy. For patients with early-stage ovarian cancer, the treatment is mainly radical surgery, followed by determining the need for additional adjuvant radiotherapy or chemotherapy based on specific pathological staging, the presence of high-risk factors for recurrence such as vascular tumor thrombus and neural invasion, and the situation of lymph node metastasis. For patients with advanced ovarian cancer, the treatment may involve debulking surgery and chemotherapy, with chemotherapy being the main treatment. Chemotherapy also needs to take into account the patient's general condition, along with local pelvic radiotherapy. These are the treatment methods for ovarian cancer, and the specific treatment plan should be selected based on staging and the patient's general condition, as well as the presence of other serious underlying diseases.


What are the symptoms of ovarian cancer?
In the early stages, ovarian cancer often doesn't show many symptoms and can be detected during gynecological examinations. However, as it progresses, symptoms such as abdominal bloating, lumps in the abdomen, and ascites may occur. The severity of these symptoms depends on the size and location of the tumor, the extent to which it has invaded nearby organs, the histological type of the tumor, and whether the malignant tumor, ovarian cancer, has metastasized to other areas or is accompanied by other complications.


How is ovarian cancer screened?
The most commonly used screening method for ovarian cancer is the B-ultrasound examination of the adnexa uteri. The B-ultrasound can detect ovarian masses and tumors, and when these are found, the possibility of ovarian cancer should be considered, necessitating further examinations for confirmation. Another method involves the tumor marker CA125, which is relatively sensitive and specific for epithelial ovarian cancer. Therefore, for ovarian cancer screening, we can perform a blood test for CA125 in conjunction with a B-ultrasound of the adnexa uteri.