What are the symptoms of ovarian cancer?

Written by Gong Chun
Oncology
Updated on September 06, 2024
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Ovarian cancer often does not present symptoms in its early stages and can be detected during gynecological examinations. Secondly, as the tumor grows, it can cause abdominal swelling and discomfort, and abdominal masses may be felt during examinations. Ascites may also develop. The severity of these symptoms depends on the size and location of the tumor, the nearby organs it invades, and the histological type of the tumor. Thirdly, if the tumor infiltrates or compresses surrounding tissues, it can also lead to abdominal pain, back pain, and pain in the lower extremities. If it compresses the pelvic veins, swelling in the lower limbs may occur. If the tumor is functional, it can produce symptoms related to excess estrogen or androgen. In its later stages, the condition may manifest as cachexia and severe anemia, among other signs of a severe illness state.

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Early Symptoms of Ovarian Cancer

Patients with ovarian cancer may have relatively hidden clinical symptoms in the early stages, possibly without any specific discomfort, or just mild lower abdominal bloating or pain. Symptoms tend to become more apparent only when the tumor progressively enlarges or when ascites occur, such as increased abdominal bloating and pain. Furthermore, during a physical examination, a solid or cystic-solid mass can be palpated in the pelvic area. Ascites can also lead to clinical symptoms such as nausea and vomiting. In the late stages, partial intestinal obstruction or symptoms related to pelvic compression may appear.

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Does ovarian cancer hyperthermic intraperitoneal chemotherapy work?

Patients with ovarian cancer are prone to peritoneal metastasis, so many patients develop ascites during the discovery of the disease or its progression. A large amount of ascites is a common concurrent symptom in patients with ovarian cancer. For patients with significant ascites like this, hyperthermic intraperitoneal chemotherapy (HIPEC) can be performed, which involves infusing chemotherapy drugs into the abdominal cavity and then combining it with thermotherapy. This treatment generally has a decent effect, especially in controlling the spread of cancer cells in the peritoneum and managing ascites.

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Can ovarian cancer be cured?

Whether ovarian cancer can be cured depends on the clinical stage of the patient, as well as the patient's sensitivity to treatment, among other factors. If it is a case of early-stage ovarian cancer, curative surgery can be performed. After surgery, based on the pathology, it can be decided whether postoperative adjuvant radiotherapy or chemotherapy is necessary. Patients with early-stage ovarian cancer who undergo surgery or postoperative adjuvant radiotherapy and chemotherapy may have hope for a cure. However, if the cancer is discovered at a late stage where it has spread extensively, such as widespread metastasis to the pelvic area, or even to distant organs like the lungs or liver, then the treatment for these patients is primarily chemotherapy. A cure is not achievable; the treatment aims to alleviate symptoms and prolong the patient's life. Thus, for patients with late-stage ovarian cancer, treatment cannot achieve a curative purpose.

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How is ovarian cancer screened?

The most commonly used screening method for ovarian cancer is the B-ultrasound examination of the adnexa uteri. The B-ultrasound can detect ovarian masses and tumors, and when these are found, the possibility of ovarian cancer should be considered, necessitating further examinations for confirmation. Another method involves the tumor marker CA125, which is relatively sensitive and specific for epithelial ovarian cancer. Therefore, for ovarian cancer screening, we can perform a blood test for CA125 in conjunction with a B-ultrasound of the adnexa uteri.

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Early symptoms of ovarian cancer

The early clinical symptoms of ovarian cancer primarily include the following aspects: 1. Discomfort and dull pain in the lower abdomen, with some patients experiencing a sensation of heaviness in the pelvis. Alongside this, patients may also experience poor appetite, nausea, belching, and a feeling of bloating in the stomach. 2. A sensation of abdominal fullness is a clinical manifestation that can appear early in ovarian cancer patients, often caused by cancerous ascites due to the disease. 3. In very few cases, early-stage ovarian cancer patients may feel a mass in the abdomen, typically in leaner patients. 4. Some early-stage patients may experience mild abdominal pain, which generally occurs intermittently and can resolve on its own without the need for medication. 5. Patients may exhibit menstrual irregularities and some endocrine symptoms, such as vaginal bleeding.