How is ovarian cancer screened?

Written by Liu Liang
Oncology
Updated on September 02, 2024
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The most commonly used screening method for ovarian cancer is the B-ultrasound examination of the adnexa uteri. The B-ultrasound can detect ovarian masses and tumors, and when these are found, the possibility of ovarian cancer should be considered, necessitating further examinations for confirmation. Another method involves the tumor marker CA125, which is relatively sensitive and specific for epithelial ovarian cancer. Therefore, for ovarian cancer screening, we can perform a blood test for CA125 in conjunction with a B-ultrasound of the adnexa uteri.

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Is ovarian cancer hereditary?

The onset of ovarian cancer may be somewhat related to family history or genetic factors. Therefore, patients with a family history of ovarian cancer may have a higher risk of developing the disease compared to the general population. However, this doesn't mean that a patient with ovarian cancer will definitely pass the condition to their offspring; it merely indicates a certain level of heredity. Furthermore, for those with a family history of breast cancer, colon cancer, and endometrial cancer, it is crucial for their descendants to undergo enhanced screenings for ovarian cancer and these diseases, as their risk of developing these conditions may be higher than that of the average person.

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Is chemotherapy effective after the recurrence of ovarian cancer?

After the recurrence of ovarian cancer, most patients can still benefit from chemotherapy again, as ovarian cancer itself is relatively sensitive to chemotherapy compared to other types of malignant tumors. If the recurrence occurs more than six months after the initial treatment, the same chemotherapy drugs used initially can still be chosen. However, if the recurrence happens within six months, the chemotherapy plan should include different drugs that were not used previously.

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Oncology
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Early Symptoms of Ovarian Cancer

Patients with ovarian cancer may have relatively hidden clinical symptoms in the early stages, possibly without any specific discomfort, or just mild lower abdominal bloating or pain. Symptoms tend to become more apparent only when the tumor progressively enlarges or when ascites occur, such as increased abdominal bloating and pain. Furthermore, during a physical examination, a solid or cystic-solid mass can be palpated in the pelvic area. Ascites can also lead to clinical symptoms such as nausea and vomiting. In the late stages, partial intestinal obstruction or symptoms related to pelvic compression may appear.

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Oncology
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How is ovarian cancer treated?

Our treatment principle is that once an ovarian tumor is detected, surgical treatment should be performed. First and foremost, we need to confirm the diagnosis. Second, we should clarify the pathological staging of the ovarian cancer to guide the treatment. It's not a single approach; it's a comprehensive treatment plan. For example, if it is early stage and there are no surgical contraindications, we can proceed with surgical treatment. After the surgery, we can provide adjunctive chemotherapy. If surgery is not immediately feasible, we can also provide neoadjuvant therapy to reduce the stage before proceeding with ovarian cancer surgery. Moreover, there is now targeted therapy and immunotherapy for ovarian cancer, so it is a comprehensive treatment plan.

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Oncology
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How is ovarian cancer diagnosed?

Ultrasound or CT scans detecting ovarian masses, in combination with biopsy or cytological examination that identify cancer cells, can diagnose ovarian cancer. A common method of biopsy includes ultrasound-guided procedures or transvaginal cul-de-sac puncture biopsy of ovarian masses, enabling clear pathological confirmation. Additionally, exploratory laparotomy or early radical surgery for ovarian cancer patients can yield a postoperative pathological diagnosis of ovarian cancer. Moreover, the presence of ascites is a common symptom in ovarian cancer patients; finding cancer cells, especially adenocarcinoma, in ascites, coupled with significantly elevated tumor marker CA125, or ultrasound or CT imagery revealing ovarian masses, can also diagnose ovarian cancer.