How is ovarian cancer screened?

Written by Liu Liang
Oncology
Updated on September 02, 2024
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The most commonly used screening method for ovarian cancer is the B-ultrasound examination of the adnexa uteri. The B-ultrasound can detect ovarian masses and tumors, and when these are found, the possibility of ovarian cancer should be considered, necessitating further examinations for confirmation. Another method involves the tumor marker CA125, which is relatively sensitive and specific for epithelial ovarian cancer. Therefore, for ovarian cancer screening, we can perform a blood test for CA125 in conjunction with a B-ultrasound of the adnexa uteri.

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Does ovarian cancer hyperthermic intraperitoneal chemotherapy work?

Patients with ovarian cancer are prone to peritoneal metastasis, so many patients develop ascites during the discovery of the disease or its progression. A large amount of ascites is a common concurrent symptom in patients with ovarian cancer. For patients with significant ascites like this, hyperthermic intraperitoneal chemotherapy (HIPEC) can be performed, which involves infusing chemotherapy drugs into the abdominal cavity and then combining it with thermotherapy. This treatment generally has a decent effect, especially in controlling the spread of cancer cells in the peritoneum and managing ascites.

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What are the symptoms and early signs of ovarian cancer?

The symptoms and early signs of ovarian cancer mainly include the following aspects. Patients may experience persistent lower abdominal pain for no apparent reason, and some patients may experience radiating pain in the vulvar area, while others may show early clinical signs of abdominal bloating. The symptoms and early signs of ovarian cancer are not very numerous. Some patients may exhibit menstrual irregularities, such as increased or decreased menstruation, prolonged periods, or irregular vaginal bleeding. A few patients may experience abnormal vaginal discharge, which can be mixed with an unusual odor and a small amount of blood.

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Will ovarian cancer recur after complete resection?

After complete removal of ovarian cancer, there is still a possibility of recurrence, especially in patients with high-risk factors. The recurrence rate can be quite high, for example, if there was rupture of the capsule, low differentiation of the pathology, presence of tumor tissue on the surface of the ovary, severe adhesion of the tumor to the surrounding areas, cancer cells found in the abdominal lavage fluid, or presence of vascular tumor thrombus and nerve invasion. Even after total removal, recurrence can still occur.

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What are the early symptoms of ovarian cancer?

The early symptoms of ovarian cancer are not severe or common clinically. Some patients may experience abdominal distension and pain. Some may have menstrual irregularities, such as prolonged or shortened menstrual cycles, increased menstrual flow, or irregular bleeding outside of menstruation. Additionally, a small number of patients may experience pelvic pain due to local tumor compression caused by ovarian cancer. This pain occasionally radiates to the perineal area and is generally mild, rarely affecting the patient's quality of life. Furthermore, a minor proportion of ovarian cancer patients, particularly those with tumors having endocrine functions, may exhibit symptoms associated with paraneoplastic syndromes.

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How long can one live with ovarian cancer?

The lifespan of ovarian cancer patients depends on several factors including the specific stage of the cancer, the patient's sensitivity and response to treatment, and the overall health of the patient, leading to significant individual variability. The cancer is typically classified into stages from one to four, with stage one being the earliest and stage four being the most advanced. Generally, patients diagnosed at an earlier stage tend to have a better prognosis and a greater chance of survival compared to those with advanced ovarian cancer. Additionally, patients in advanced stages who respond well to treatments like chemotherapy typically have a better prognosis and longer survival times compared to those who are less responsive to such treatments. Hence, it is impossible to generalize as the individual differences are substantial.