Early treatment methods for ovarian cancer

Written by Gong Chun

Oncology

Updated on September 05, 2024

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The treatment methods for early-stage ovarian cancer should first and foremost include a clear diagnosis and staging. If the staging indicates an early stage, then surgical treatment can be applied. There are many surgical options available, such as cytoreductive surgery, interval debulking surgery, second-look laparotomy, and direct tumor cell reduction surgery. After the surgery, adjuvant chemotherapy can be administered for treatment.

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Is ovarian cancer curable?

Early-stage ovarian cancer patients, meaning those without extensive ascites buildup, and without widespread implant metastasis in the pelvic and abdominal cavity, and without metastasis to distant organs like the liver and lungs. These very early-stage ovarian cancer patients can undergo radical surgery. Postoperative treatment decisions, such as whether postoperative adjuvant radiotherapy or chemotherapy is needed, are based on the postoperative pathological report, which looks for high-risk factors for recurrence such as vascular cancer emboli or neural invasion. Through these treatment approaches, very early-stage ovarian cancer patients can achieve a cure, but this is not absolute. It's not guaranteed that every early-stage ovarian cancer patient can be cured, as there are individual differences. Clinically, if there is no recurrence or metastasis within five years, it is considered a cure.

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Is ovarian cancer hereditary?

The onset of ovarian cancer may be somewhat related to family history or genetic factors. Therefore, patients with a family history of ovarian cancer may have a higher risk of developing the disease compared to the general population. However, this doesn't mean that a patient with ovarian cancer will definitely pass the condition to their offspring; it merely indicates a certain level of heredity. Furthermore, for those with a family history of breast cancer, colon cancer, and endometrial cancer, it is crucial for their descendants to undergo enhanced screenings for ovarian cancer and these diseases, as their risk of developing these conditions may be higher than that of the average person.

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How is ovarian cancer diagnosed?

Early screening for ovarian cancer allows for about 20% of cases to be diagnosed in their early stages. Detection generally follows these procedures: 1. Routine gynecological health check-ups. 2. Visiting a hospital due to certain symptoms. 3. Ovarian cancer screening. Common methods include transvaginal ultrasound and serum CA125 testing. Additional tests include tumor marker CA125 and checks for AFP, CA19-9, and CEA. Ultrasonography (B-ultrasound) can preliminarily determine the tumor size, shape, solidity, location, and its relation to surrounding organs. CT scans and MRI can further clarify the tumor's nature and the extent of invasion into the abdominal and pelvic organs. If necessary, gastroscopy can be performed to rule out primary gastrointestinal tumors, and if economic conditions allow, a PADCT scan can also be conducted.

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What are the symptoms of ovarian cancer?

Some early symptoms of ovarian cancer patients include a lump in the abdomen that can be felt during gynecological examination or by the patients themselves. In advanced ovarian cancer, as the tumor progressively enlarges, there may be symptoms like abdominal pain, bloating, decreased appetite, and weight loss. Moreover, the tumor may compress other organs in the pelvic cavity, causing symptoms such as a feeling of heaviness in the lower abdomen or even constipation. Additionally, many patients with ovarian cancer may develop significant ascites, which can also cause abdominal distension, decreased appetite, and even nausea and vomiting, along with other gastrointestinal symptoms.

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Can ovarian cancer be detected by transvaginal ultrasound?

Ovarian cancer can generally be detected through a transvaginal ultrasound. During this procedure, we can find cystic or cystic-solid, or a solid mass in the ovaries. If a blood test for tumor markers shows a significant increase in CA125, especially in combination with a large amount of ascites, we must strongly suspect ovarian cancer. In such cases, patients should undergo a tumor biopsy. By taking a biopsy and confirming it pathologically, we can definitively diagnose ovarian cancer. Therefore, most ovarian cancer patients can indeed be detected through a transvaginal ultrasound.