Liver cancer


Is the right shoulder pain from liver cancer muscular pain?
Many cancer patients do not exhibit obvious symptoms after becoming ill. This is particularly true for many liver cancer patients who do not feel anything unusual after contracting the disease, leading to a lack of timely detection and treatment. By the time they are diagnosed, the disease has often already reached an advanced stage. At this advanced stage, treatment becomes quite difficult. If a patient experiences severe pain in the right shoulder, it generally indicates that the liver cancer has reached a late stage. The pain during this period has no specific characteristics; it is simply a sensation of pain.


Does early-stage liver cancer cause the complexion to become dark?
Patients with early-stage liver cancer do not experience darkening of the facial complexion. This is because early-stage liver cancer primarily refers to carcinoma in situ of the liver and some small liver cancers. Since the tumors are small and the affected area is limited, they generally cause few symptoms clinically. Some patients may experience mild fatigue and a decrease in appetite, but these do not lead to changes in the complexion. Only when the liver cancer progresses to the middle or late stages, causing damage to liver cell functions or when the pathology metastasizes, leading to damage to multiple organ functions, can there be some changes in facial complexion. For example, patients may exhibit pale complexions due to moderate to severe anemia. Some patients may have yellowing of the skin due to obstructive jaundice or hepatocellular jaundice. Additionally, some patients may show darkening of the facial complexion due to abnormal hormone secretion.


Is the alpha-fetoprotein high in the early stage of liver cancer?
Patients with liver cancer may not necessarily have elevated carcinoembryonic antigen (CEA) levels in the early stages. CEA, a commonly used tumor marker, tends to increase in various types of malignancies. However, an elevation in CEA is not necessarily linked to the occurrence of malignant tumors. Many patients with early-stage tumors, including liver cancer, may not have elevated CEA levels at diagnosis. Conversely, elevated CEA levels in some patients may be due to benign conditions and not necessarily indicate malignancy. Therefore, it is unreasonable to determine the presence of liver cancer solely based on the elevation of CEA.


Symptoms of late-stage liver cancer deterioration
If liver cancer reaches an advanced stage, many symptoms will appear. For example, there will be pain in the liver area due to the tumor's growth pulling on the liver capsule, causing persistent swelling in the upper right part or stomach pain. If the tumor invades the pectoral muscles, it may cause referred pain in the right shoulder or back. Some patients may experience an enlarged liver due to the increased size of the tumor, which feels painful when pressed. Additionally, the increase and pressure from the tumor can obstruct bile excretion, leading to jaundice, and symptoms of cirrhosis may also appear. In general, the main symptoms of advanced liver cancer include fever, fatigue, loss of appetite, and weight loss. If the condition worsens, metastatic symptoms may occur; lung metastasis can cause the patient to cough and expel phlegm, and bone metastasis can cause localized pain and lumps.


Does liver cancer cause nosebleeds in its early stages?
Patients with early-stage liver cancer generally do not exhibit clinical symptoms of nosebleeds. Nosebleeds are a clinical manifestation of late-stage liver cancer. Early-stage liver cancer patients usually have atypical symptoms, which may include tenderness in the liver area, decreased appetite, abdominal bloating, and symptoms of indigestion. As the disease progresses, the liver cancer invades surrounding tissues and metastasizes to distant sites, leading to liver function impairment and coagulation disorders, which can result in nosebleeds. Some patients may also develop splenic hyperfunction due to liver damage, leading to a decrease in platelets, which can also cause nosebleeds. Additionally, some patients in the late stages may develop disseminated intravascular coagulation, leading to spontaneous internal and mucosal bleeding, clinically manifesting as nosebleeds.


Can hepatitis B turn into liver cancer?
Hepatitis B can gradually develop into cirrhosis or liver cancer. Therefore, if a hepatitis B virus infection is detected, it needs attention. If the hepatitis B surface antigen is positive in the HBV "two-and-a-half" test, it indicates a hepatitis B virus infection. Once infected with the hepatitis B virus, it is necessary to regularly check liver function and hepatitis B virus DNA, as well as have abdominal ultrasounds. If an increase in transaminases is found, it indicates the transformation into chronic hepatitis B, necessitating liver-protecting and enzyme-lowering treatments. If the hepatitis B virus DNA exceeds a certain value, antiviral treatment is also needed. After being infected with the hepatitis B virus, it is crucial to rest and avoid excessive fatigue and staying up late.


Liver cancer B-ultrasound manifestations
Generally speaking, for diseases of the hepatobiliary system, most of us conduct examinations using ultrasound because it is very convenient, safe, involves no radiation, and the results are relatively quick. Generally, liver cancer can appear as hypoechoic, hyperechoic, or mixed echogenicity on ultrasound. Most such liver cancer nodules may have a complete capsule, but some may not have a complete capsule. Overall, this type of liver cancer tends to grow expansively and invasively, compressing the surrounding normal liver tissue, and possibly showing some halo signs around it. The vast majority of liver cancers do not occur independently; they usually develop gradually from cirrhosis. Therefore, there is often an enlargement of the portal vein, and in some cases of liver cancer with metastasis, thrombosis in the portal vein can be seen.


What are the symptoms on the face in the early stages of liver cancer?
In early-stage liver cancer patients, symptoms generally do not appear on their faces. This is because the tumors in early liver cancer are small, the lesions are localized, with shallow infiltration, no invasion of surrounding tissues or metastasis to distant organs, and thus, less damage to liver cells. Therefore, most cases do not show obvious symptoms clinically. Only when the lesions progress further do symptoms of disease dissemination appear in patients. These symptoms include persistent pain in the liver area, a significant decrease in appetite, fatigue, fever, and weight loss. Some patients may also experience symptoms of metastatic lesions, such as pain in bone metastases, headache, vomiting, hemiplegia, and aphasia in brain metastases, and cough, breathing difficulties, and chest pain in lung metastases.


Is primary liver cancer hereditary?
The occurrence of tumors is related to multiple factors including genetics, environment, and the lifestyle habits of the patient. Therefore, primary liver cancer does have a genetic component. If parents, siblings, grandparents, etc., have a history of liver cancer, the offspring of such patients might have a higher probability of developing liver cancer compared to the general population. However, it's not absolute, as it also depends on other factors like environment, personal dietary habits, lifestyle habits, whether one has hepatitis, alcoholic liver cirrhosis, and other similar factors. Thus, those with a family history of liver cancer are likely to have a higher risk of developing the condition and should be more vigilant about disease screening. Screening should be more frequent than for the general population, but this is not an absolute rule.


Does primary liver cancer have a genetic basis?
Primary liver cancer is generally not certain to be hereditary, but it may be somewhat related to genetics. For example, there are often phenomena of family and regional clustering of liver cancer. Current research believes that primary liver cancer, commonly referred to as liver cancer, is the result of a combination of factors, closely associated with hepatitis virus infection, aflatoxin infection, and contaminated drinking water. Common scenarios include hepatitis B virus infection leading to hepatitis B followed by cirrhosis, which can further develop into primary liver cancer. Also, long-term alcohol abuse leading to alcoholic cirrhosis can also result in liver cancer.