Common symptoms of primary liver cancer

Written by Liu Liang
Oncology
Updated on May 09, 2025
00:00
00:00

The initial symptoms of primary liver cancer are mostly pain in the liver area, which commonly presents as abdominal pain. Some patients may also experience bloating, fatigue, and weight loss as systemic symptoms. In advanced-stage liver cancer patients, there can be an enlargement of the liver, meaning a palpable enlarged mass can be felt in the abdomen. Other symptoms include jaundice and ascites, which can cause abdominal bloating. Upon physical examination, an obvious increase in abdominal girth and abdominal distension can be noted. Moreover, patients with advanced liver cancer may also suffer from complications such as upper gastrointestinal bleeding, rupture and bleeding of the liver cancer nodules, liver failure, and even hepatic encephalopathy, among others.

Other Voices

doctor image
home-news-image
Written by Liu Liang
Oncology
59sec home-news-image

Is primary liver cancer hereditary?

The occurrence of tumors is related to multiple factors including genetics, environment, and the lifestyle habits of the patient. Therefore, primary liver cancer does have a genetic component. If parents, siblings, grandparents, etc., have a history of liver cancer, the offspring of such patients might have a higher probability of developing liver cancer compared to the general population. However, it's not absolute, as it also depends on other factors like environment, personal dietary habits, lifestyle habits, whether one has hepatitis, alcoholic liver cirrhosis, and other similar factors. Thus, those with a family history of liver cancer are likely to have a higher risk of developing the condition and should be more vigilant about disease screening. Screening should be more frequent than for the general population, but this is not an absolute rule.

doctor image
home-news-image
Written by Cui Fang Bo
Oncology
53sec home-news-image

Is the right shoulder pain from liver cancer persistent?

For patients with liver cancer, if there is pain in the right shoulder, it is not necessarily continuous, which depends on the specific cause of the right shoulder pain. If the pain is caused by bone metastasis of liver cancer to the right shoulder, the pain is often severe and persistent. Bone is one of the more common sites of metastasis for liver cancer. For bone metastases of liver cancer, we can use imaging studies to detect clear bone destruction at the metastatic sites on X-rays, CT scans, and MRI. If the right shoulder pain in liver cancer patients is caused by other benign conditions, the pain may not necessarily be persistent. For instance, liver cancer patients may also experience shoulder pain due to other conditions such as rotator cuff injuries, periarthritis, or minor trauma, but this pain is not necessarily continuous.

doctor image
home-news-image
Written by Liu Liang
Oncology
1min 10sec home-news-image

What to do if vomiting occurs in liver cancer?

Liver cancer is divided into two main pathological types, the first being hepatocellular carcinoma, which is the most common, and the other being cholangiocellular carcinoma. Clinically, vomiting is also a common symptom of liver cancer. For symptomatic treatment, we can provide gastric protection and administer antiemetic drugs such as stomach comfort, but these are only symptomatic treatments and do not cure the root cause. The key is still to treat the liver cancer itself, as the symptoms will only alleviate once the cancer is under control. For advanced hepatocellular carcinoma, targeted therapies like sorafenib are available. If it is cholangiocellular carcinoma, and symptoms like vomiting and jaundice appear, which may be obstructive symptoms, then a surgical procedure in hepato-biliary surgery to drain the bile can be performed, which can also alleviate the symptoms of vomiting. (Medications should be used under the guidance of a doctor.)

doctor image
home-news-image
Written by Yan Chun
Oncology
1min 8sec home-news-image

Does early-stage liver cancer cause the complexion to become dark?

Patients with early-stage liver cancer do not experience darkening of the facial complexion. This is because early-stage liver cancer primarily refers to carcinoma in situ of the liver and some small liver cancers. Since the tumors are small and the affected area is limited, they generally cause few symptoms clinically. Some patients may experience mild fatigue and a decrease in appetite, but these do not lead to changes in the complexion. Only when the liver cancer progresses to the middle or late stages, causing damage to liver cell functions or when the pathology metastasizes, leading to damage to multiple organ functions, can there be some changes in facial complexion. For example, patients may exhibit pale complexions due to moderate to severe anemia. Some patients may have yellowing of the skin due to obstructive jaundice or hepatocellular jaundice. Additionally, some patients may show darkening of the facial complexion due to abnormal hormone secretion.

doctor image
home-news-image
Written by Yan Chun
Oncology
1min 2sec home-news-image

Does early-stage liver cancer cause itchy skin?

Liver cancer is one of the common malignant tumors in the digestive system. In the early stages of liver cancer, most patients do not exhibit symptoms of skin itching. It is only when the cancer progresses and causes obstructive jaundice that patients clinically develop symptoms of skin itching. Early-stage liver cancer patients typically do not show typical clinical symptoms, or they may not have any significant symptoms at all. This is because early-stage liver cancer lesions are small and localized, without external invasion or metastasis. Therefore, the impact on the entire body is minimal, and clinically it generally manifests as mild abdominal bloating, discomfort, nausea, diarrhea, and some patients may experience a dull ache or discomfort in the liver area. Because the symptoms of early-stage liver cancer are atypical, many patients are already in the middle to late stages by the time they seek medical attention, missing the opportunity for clinical cure.