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Kawasaki disease
Can Kawasaki disease heal itself?
Kawasaki disease, also known as mucocutaneous lymph node syndrome, is a disease with unclear etiology and unclear pathogenesis. It commonly affects infants and young children, with 80% of cases occurring in children under five years old, and the male to female incidence ratio being 1.5:1. Kawasaki disease is a self-limiting disease, and most cases have a good prognosis. Recurrences are seen in 1%-2% of affected children. Children without coronary artery lesions also need a comprehensive physical examination, generally recommended at one month, three months, six months, and annually or biannually for up to two years, including physical examination, electrocardiogram, and echocardiography. Without effective treatment, 15%-20% of affected children may develop coronary artery aneurysms, and they should be closely followed long-term, with follow-up every six to twelve months. Coronary artery aneurysms often resolve themselves within two years after the disease, but often leave behind abnormalities such as thickened vessel walls and reduced elasticity. Large aneurysms often do not completely resolve and may lead to thrombosis or narrowing of the vessel lumen. Kawasaki disease is also a cause of acquired heart disease, so timely and effective treatment is essential to prevent cardiac issues. Once Kawasaki disease develops, it is advised to seek prompt hospital treatment to manage the condition effectively.
Is Kawasaki disease characterized by eye discharge?
Kawasaki disease is an autoimmune vasculitis that can affect blood vessels throughout the body and various organs, but the most severe impact is typically on the coronary arteries, which can lead to dilation of the coronary arteries or the possibility of forming coronary artery aneurysms. The disease can cause conjunctival congestion, but this is a manifestation of aseptic conjunctivitis, meaning it does not cause, nor does it result in, purulent secretions, in other words, it does not cause eye discharge. Therefore, if a patient with Kawasaki disease has purulent eye discharge, it is possible that they have a concurrent bacterial conjunctivitis. Thus, generally, eyes affected by Kawasaki disease do not have eye discharge but may appear dry and red.
What is Kawasaki disease? Is it contagious?
Kawasaki disease is a common pediatric febrile rash disease, also known as mucocutaneous lymph node syndrome. It is a systemic vasculitis syndrome mediated by immune mechanisms. Kawasaki disease may be caused by acute immune dysregulation due to infectious factors, and genetic factors may be related to the acute onset of the disease. Therefore, Kawasaki disease is not contagious, and contact with children with Kawasaki disease will not lead to transmission. Kawasaki disease generally occurs in infants and young children, and there is no clear seasonal pattern to its occurrence, nor significant gender differences.
How is Kawasaki disease diagnosed?
Kawasaki disease, also known as mucocutaneous lymph node syndrome, is an acute febrile rash disease characterized primarily by inflammation of medium and small arteries throughout the body, with a self-limiting nature. Clinically, it mainly presents with fever, rash, mucosal lesions, conjunctival congestion, and non-suppurative enlargement of cervical lymph nodes. If untreated, 20% of cases can lead to coronary artery damage. To diagnose this disease, in addition to typical clinical manifestations, attention must also be paid to various tests such as blood tests, immunological tests, and ultrasound examinations for a comprehensive assessment. Although the clinical characteristics are largely indicative of the disease, ultrasound examination is crucial to check for any dilation of the coronary arteries.
Does Kawasaki disease affect lifespan?
Kawasaki disease, also known as mucocutaneous lymph node syndrome, has an unclear pathogenesis. Its pathological changes primarily involve a systemic circulatory disease characterized by vasculitis. A severe complication can lead to cardiac lesions. Generally, Kawasaki disease is self-limiting and most cases have a good prognosis. However, if Kawasaki disease is not effectively treated and results in associated coronary artery aneurysms or large artery aneurysms, it could lead to acquired heart disease. Such cardiac issues could potentially affect cardiac function later on. This might impact lifespan, but if Kawasaki disease is treated aggressively and effectively, the prognosis is good and the impact on future health is minimal.
Kawasaki disease incubation period
Kawasaki disease, also known as mucocutaneous lymph node syndrome, is a common pediatric fever and rash illness, primarily a systemic small vessel vasculitis. Kawasaki disease is not contagious, so it has no incubation period; only infectious diseases have incubation periods. If it were contagious, typical manifestations would include persistent high fever, pinpoint appearances around the eyes and mouth, typical rash, swelling of the hands and feet, and non-purulent swelling of the cervical lymph nodes. Therefore, Kawasaki disease has no incubation period and is a vasculitis mediated by immune mechanisms.
Kawasaki Disease Aspirin Side Effects
Aspirin is necessary for Kawasaki disease. Considering the pros and cons, aspirin must be used in cases of Kawasaki disease, initially in high doses. However, aspirin indeed has side effects. Some say aspirin is contraindicated for children, as its consumption can lead to Reye's Syndrome. This syndrome involves widespread mitochondrial damage following the intake of salicylate drugs during viral infection recovery, posing risks to the liver and brain. Without timely treatment, it could likely lead to liver and kidney failure, brain damage, or even death. Thus, aside from specific diseases, the use of aspirin is strictly prohibited. These specific diseases include Kawasaki disease, rheumatoid arthritis, etc. Therefore, the use of aspirin in Kawasaki disease is necessary, but it can indeed lead to some side effects.
How to alleviate vomiting in Kawasaki disease
When children with Kawasaki disease experience vomiting, the first step is to refrain from eating and drinking, including water, for one to two hours after vomiting to avoid burdening the stomach and intestines. If vomiting subsides after fasting, there is no need for medication temporarily. However, if there is no significant relief and bloating is evident, it is necessary to treat for bowel movement and gas release. At this time, oral medications that aid in digestion, such as digestive tonics, are acceptable. If relief is still not achieved, intravenous fluid supplementation and medications that enhance gastrointestinal motility can be administered. Parents can also keep the abdomen warm and, centering around the navel, perform clockwise abdominal massages to help alleviate the symptoms of vomiting.
Causes of secondary recurrence of Kawasaki disease
Kawasaki disease, also known as mucocutaneous lymph node syndrome, commonly affects children and infants under five years old. It is an acute, systemic vasculitic disease. Clinically, it is primarily characterized by persistent fever, bilateral conjunctival congestion, cracked lips, strawberry tongue, rash, hard swelling of hands and feet, fingertip desquamation, and enlargement of cervical lymph nodes. In severe cases, it can lead to coronary artery dilation, coronary artery aneurysms, and thrombotic obstruction. The exact cause of Kawasaki disease is not very clear, but it is mainly believed to be related to infections. The probability of secondary recurrence of Kawasaki disease is about 2%, and its causes mainly have to do with infections, immune factors of the body, genetic factors, and so on.
Kawasaki disease peeling symptoms
Kawasaki disease is a disease with unclear etiology and unclear pathogenesis of the autoimmune system. Its main pathological change is systemic vasculitis, commonly occurring in the coronary arteries. At the onset, symptoms in the hands and feet include stiff swelling and erythema during the acute phase. In the recovery phase, membranous peeling occurs at the junction of the skin and the nail base of fingers and toes, and there are transverse grooves in the nails. In severe cases, the nails of the fingers and toes may also fall off. Additionally, its skin manifestations include polymorphic skin plaques and scarlet fever-like rashes, which commonly appear in the first week of the disease, with redness and peeling of the skin around the anus.