Kawasaki disease peeling symptoms

Written by Li Jiao Yan
Neonatology
Updated on November 26, 2024
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Kawasaki disease is a disease with unclear etiology and unclear pathogenesis of the autoimmune system. Its main pathological change is systemic vasculitis, commonly occurring in the coronary arteries. At the onset, symptoms in the hands and feet include stiff swelling and erythema during the acute phase. In the recovery phase, membranous peeling occurs at the junction of the skin and the nail base of fingers and toes, and there are transverse grooves in the nails. In severe cases, the nails of the fingers and toes may also fall off. Additionally, its skin manifestations include polymorphic skin plaques and scarlet fever-like rashes, which commonly appear in the first week of the disease, with redness and peeling of the skin around the anus.

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Written by Yan Xin Liang
Pediatrics
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How long does Kawasaki disease require hospitalization?

Kawasaki disease is an autoimmune vasculitis, primarily concerning because it affects the coronary arteries of the heart. Without effective treatment, some cases can lead to coronary artery dilation and even the formation of coronary artery aneurysms. Therefore, hospitalization is generally recommended during the acute phase of Kawasaki disease. During hospitalization, treatment typically involves the use of intravenous immunoglobulin and aspirin. After treatment with intravenous immunoglobulin, the body temperature generally begins to decrease gradually. Once the body temperature has stabilized for about three days and there are no complications, the patient can usually be discharged, so most hospital stays last about 5-7 days. (Medication should be taken under the guidance of a doctor.)

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Written by Li Jiao Yan
Neonatology
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Does Kawasaki disease rash itch?

Kawasaki disease, once called mucocutaneous lymph node syndrome, is a disease of unknown cause and unclear pathogenesis. It is characterized by systemic vasculitis. Clinically, it mainly presents with fever, conjunctival congestion, cracked lips, congested oral mucosa, diffuse congestion, strawberry tongue, acute stage swelling and erythema of the hands and feet, polymorphous rash, and scarlet fever-like skin rash. It is often associated with unilateral or bilateral lymphadenopathy, which is not red on the surface, but the lymph nodes are hard and tender to the touch. It frequently involves complications such as myocarditis or pericarditis, with common coronary artery damage. The rash seen in Kawasaki disease is a manifestation of vasculitis and is generally non-itchy.

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Written by Yan Xin Liang
Pediatrics
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Is Kawasaki disease characterized by eye discharge?

Kawasaki disease is an autoimmune vasculitis that can affect blood vessels throughout the body and various organs, but the most severe impact is typically on the coronary arteries, which can lead to dilation of the coronary arteries or the possibility of forming coronary artery aneurysms. The disease can cause conjunctival congestion, but this is a manifestation of aseptic conjunctivitis, meaning it does not cause, nor does it result in, purulent secretions, in other words, it does not cause eye discharge. Therefore, if a patient with Kawasaki disease has purulent eye discharge, it is possible that they have a concurrent bacterial conjunctivitis. Thus, generally, eyes affected by Kawasaki disease do not have eye discharge but may appear dry and red.

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Written by Li Jiao Yan
Neonatology
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Does Kawasaki disease cause a runny nose?

Kawasaki disease, also known as mucocutaneous lymph node syndrome, primarily presents with repeated high fevers that do not respond to antibiotics, conjunctival congestion, diffuse oral congestion, chapped and congested lips, polymorphic erythema and scarlatiniform rashes on the skin, and unilateral or bilateral cervical lymphadenopathy. The cause of Kawasaki disease remains unclear, but studies suggest that respiratory or gastrointestinal infections may be common prodromal symptoms, indicating that the onset might be related to infections, though no contagious phenomena have been identified to date. Kawasaki disease might show prodromal signs such as upper respiratory infections, characterized by symptoms like a runny nose and cough, or gastrointestinal symptoms such as diarrhea and vomiting, which suggests that a runny nose might be a manifestation of Kawasaki disease.

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Written by Li Jiao Yan
Neonatology
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Can Kawasaki disease be cured?

Kawasaki disease, also known as mucocutaneous lymph node syndrome, has an unclear pathogenesis. The primary pathological change is systemic vasculitis. It commonly affects infants and young children, with 80% of cases occurring in children under five years of age. Kawasaki disease is a self-limiting condition, and most cases have a good prognosis. However, there is a 1% to 2% chance of recurrence. If not effectively treated, 15% to 25% of cases may develop coronary artery aneurysms. These aneurysms often resolve on their own within two years after the disease, but often leave behind abnormalities such as thickening of the vessel wall and decreased elasticity. Larger aneurysms may not completely resolve and can lead to thrombosis or narrowing of the vessel. Kawasaki disease is also one of the causes of acquired heart disease in children. Therefore, Kawasaki disease should be treated promptly and effectively to prevent severe complications.