Can Kawasaki disease heal itself?

Written by Li Jiao Yan
Neonatology
Updated on February 07, 2025
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Kawasaki disease, also known as mucocutaneous lymph node syndrome, is a disease with unclear etiology and unclear pathogenesis. It commonly affects infants and young children, with 80% of cases occurring in children under five years old, and the male to female incidence ratio being 1.5:1. Kawasaki disease is a self-limiting disease, and most cases have a good prognosis. Recurrences are seen in 1%-2% of affected children. Children without coronary artery lesions also need a comprehensive physical examination, generally recommended at one month, three months, six months, and annually or biannually for up to two years, including physical examination, electrocardiogram, and echocardiography. Without effective treatment, 15%-20% of affected children may develop coronary artery aneurysms, and they should be closely followed long-term, with follow-up every six to twelve months. Coronary artery aneurysms often resolve themselves within two years after the disease, but often leave behind abnormalities such as thickened vessel walls and reduced elasticity. Large aneurysms often do not completely resolve and may lead to thrombosis or narrowing of the vessel lumen. Kawasaki disease is also a cause of acquired heart disease, so timely and effective treatment is essential to prevent cardiac issues. Once Kawasaki disease develops, it is advised to seek prompt hospital treatment to manage the condition effectively.

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Written by Zeng Hai Jiang
Pediatrics
44sec home-news-image

Kawasaki Disease and Purpura Differences

The clinical manifestations of Kawasaki disease include fever lasting more than five days, ineffective antibiotic treatment, rashes, transient swelling of the cervical lymph nodes, conjunctival congestion, strawberry tongue, cracked lips, hard swelling of fingers and toes, and desquamation around the nails and anal region during the recovery phase. Allergic purpura is mainly manifested by rashes, which are generally hemorrhagic rashes below the buttocks, symmetrical on the lower limbs, raised above the skin surface, and usually without fever. Besides rashes, allergic purpura can also involve joint pain, abdominal pain, or allergic purpuric nephritis among other conditions.

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Written by Li Jiao Yan
Neonatology
1min 23sec home-news-image

Is the spirit of Kawasaki disease good?

Kawasaki disease, also known as mucocutaneous lymph node syndrome, has an unclear cause and is generally prevalent in infants and young children, with 80% of cases occurring in children under five years old. The mechanism of the disease is also not very clear. Its main pathological presentation is systemic vasculitis, often involving the coronary arteries. The primary clinical symptoms include high fever, which is unresponsive to antibiotic treatment, conjunctival congestion, diffuse oral congestion, strawberry tongue, indurative edema of the hands and feet, and palmoplantar erythema. Additionally, it may affect the heart, leading to conditions such as pericarditis, myocarditis, endocarditis, and arrhythmias. During the acute phase of Kawasaki disease, the high fever and diffuse oral mucosal congestion can affect the child's mental state. If the heart is involved, there may be abnormalities in heart rate and heart function, which can also lead to a poor mental state. Therefore, if Kawasaki disease is confirmed, it definitely requires active treatment.

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Written by Li Jiao Yan
Neonatology
1min 7sec home-news-image

What is Kawasaki disease?

Kawasaki disease is a disease possibly related to viruses. Currently, the exact cause of Kawasaki disease is unclear, and the mechanism of its onset is also not well understood. It is characterized primarily by systemic vasculitis and is an acute febrile exanthematous disease. Clinically, it presents with symptoms such as rash, fever, conjunctival congestion, cracked lips, oral mucosal congestion, enlarged cervical lymph nodes, and peeling of the skin on the extremities. The cause of Kawasaki disease is unclear, but various viral infections observed clinically could potentially exacerbate the progression of Kawasaki disease. It mainly affects the coronary arteries, so there is a certain link between Kawasaki disease and viruses. However, it is not necessarily the direct cause of Kawasaki disease but could worsen or be a concomitant disease.

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Written by Li Jiao Yan
Neonatology
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What should not be eaten with Kawasaki disease?

One of the main pathological changes in Kawasaki disease is systemic vasculitis. Clinically, common symptoms include fever, high fever, recurrent fever, conjunctival congestion, significant oral mucosal congestion, strawberry tongue, enlargement of neck lymph nodes, and peeling of the hands and feet. In cases of Kawasaki disease, oral mucosal congestion is a common complication, hence during the period of Kawasaki disease, it is advised not to consume irritating, spicy, or hot foods. These might exacerbate the child's discomfort, affect their nutrient absorption, and potentially worsen the condition. Therefore, during the illness, it is preferable to focus on bland, easy-to-digest foods.

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Written by Li Jiao Yan
Neonatology
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Is Kawasaki disease serious?

Kawasaki disease is an etiologically unclear disease with a not well-understood pathogenesis. The principal pathological change involves inflammatory changes in the systemic blood vessels, which can affect the coronary arteries and lead to coronary artery aneurysms and dilation. Kawasaki disease is self-limiting, and most cases resolve well, with recurrences seen in 1-2% of cases. For patients without coronary artery lesions, comprehensive examinations are required 1 month, 3 months, 6 months, and 1-2 years after discharge, including physical examinations, electrocardiograms, and echocardiograms, mainly to assess the heart's condition. If not effectively treated, 15-20% may develop coronary artery aneurysms; such cases need semi-annual or annual medical check-ups. Coronary artery aneurysms often self-resolve within two years post-diagnosis, typically leaving functional abnormalities such as thickening of the vessel wall and reduced elasticity. Major artery aneurysms often do not disappear completely and can lead to thrombosis or narrowing of the vessel lumen. Kawasaki disease is one of the common causes of acquired heart disease in children; therefore, if Kawasaki disease is accompanied by severe coronary damage, it may heal well but could lead to heart disease. If it is not a severe case of Kawasaki disease, timely treatment can still result in a good recovery.