Systemic lupus erythematosus is a disease that affects the entire body system, so there are generally systemic symptoms. The most common symptoms are bone and joint pain, and muscle pain. Some patients may show symptoms related to the skin and mucous membranes, mainly presenting as butterfly-shaped erythema, discoid erythema, and oral mucosal ulcers. In severe cases, patients may experience problems with the visceral system, mainly affecting the kidneys, primarily presenting as significant proteinuria in routine urine tests. Additionally, severe cases may even present with neurological and psychiatric issues, mainly exhibiting restlessness, hallucinations, paranoia, delusions, and various forms of cerebral infarction, cerebral hemorrhage, and other conditions.