Systemic lupus erythematosus is a multi-system damage and is an autoimmune disease that cannot be cured. It can only be managed with medications to control the condition, alleviate symptoms, delay complications, and thereby improve quality of life. This is the overall principle and goal in treating systemic lupus erythematosus. Once diagnosed with lupus, it is essential to classify the type and determine whether it is in an active phase to adopt appropriate treatment measures. The main treatments are corticosteroids and immunomodulators, with the dosage of corticosteroids varying according to the severity of the condition. (Specific medications should be used under the guidance of a doctor.)