Firstly, whether systemic lupus erythematosus (SLE) is severe cannot be generalized. It is an autoimmune disease that cannot be completely cured and can cause damage to multiple systems and organs, leading to serious complications. Therefore, it is crucial to conduct a clinical analysis and assess the severity of the condition as mild, moderate, or severe after diagnosis. Furthermore, if severe anemia or a decrease in platelets occurs, the condition is relatively severe, and the presence of oliguria or anuria or central nervous system damage, this is known as lupus crisis. These conditions can be life-threatening, even leading to death. In such cases, the condition is relatively critical, and it is essential to actively treat and control the condition. Once the condition stabilizes, the medication dosage should be gradually reduced to maintain stability.