Rheumatoid arthritis commonly occurs at what age?

Written by Li Jing
Rheumatology
Updated on September 02, 2024
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Rheumatoid arthritis is primarily a chronic systemic autoimmune disease characterized by pain in multiple joints throughout the body. The causes of the disease are not yet clear, but it is believed to be related to a combination of genetic, infectious, and environmental factors. The main pathological basis of the disease is synovitis. It commonly occurs in individuals aged between 35 and 50, and is more prevalent in females, with a significantly higher incidence rate in women than in men. Additionally, this disease can lead to disability and loss of work capacity. Therefore, early diagnosis and standard treatment are crucial. Once the condition stabilizes, the dosage should be gradually reduced to maintain the disease in a stable state.

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Written by Liu Li Ning
Rheumatology
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How should rheumatoid arthritis be treated?

The treatment of rheumatoid arthritis includes several aspects. First, general treatment: keep a light diet, avoid spicy and stimulant foods, ensure joints are kept warm, and avoid excessive fatigue. Second, medication treatment: during acute flare-ups, non-steroidal anti-inflammatory drugs such as diclofenac sodium or etoricoxib can be used, possibly combined with low doses of corticosteroids. During stable phases, immunosuppressants such as methotrexate or leflunomide are needed. If conventional treatments are ineffective, biological agents like adalimumab or tofacitinib can be combined. Most patients can effectively control their condition after combined treatment. Third, traditional Chinese medicine: alongside Western medicine, Chinese herbal medicine such as total glucosides of paeony or tripterygium wilfordii polyglycoside can be used.

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Written by Liu Li Ning
Rheumatology
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How is rheumatoid arthritis treated?

The treatment of rheumatoid arthritis is divided into general treatment and pharmacological treatment. General treatment mainly involves avoiding overexertion, having a light diet, and not staying up late. Pharmacological treatment is mainly divided into treatment during the acute flare-up phase and the remission phase. The acute phase focuses on anti-inflammatory and pain relief treatments, with non-steroidal anti-inflammatory drugs (NSAIDs) as the first choice, such as etoricoxib, meloxicam, or celecoxib. If the effect is not satisfactory, low-dose corticosteroid therapy may be combined. In the remission phase, slow-acting anti-rheumatic drugs are preferred, such as methotrexate, leflunomide, or sulfasalazine. If the slow-acting anti-rheumatic drugs are not effective, biologic agents such as tumor necrosis factor antagonists or JAK inhibitors may be combined.

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Written by Wang Cheng Lin
Orthopedics
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The difference between arthritis and rheumatoid arthritis

The difference between arthritis and rheumatoid arthritis is significant. Arthritis is a degenerative lesion caused by factors such as obesity, overuse, and trauma, which lead to the degeneration of joint cartilage. Rheumatoid arthritis is caused by acute or chronic inflammation of the connective tissue, commonly referred to as rheumatic fever. Clinically, it is mainly characterized by migratory pain, redness and swelling in the joints and muscles. The cause of rheumatoid arthritis is not yet definite in clinical practice, and the treatments are different. Osteoarthritis mainly results from cartilage degeneration and can be managed with conservative treatment in its early stages, while surgery might be required in the later stages. The treatment for rheumatoid arthritis primarily relies on medications to alleviate symptoms, and this condition may eventually lead to significant deformities of the hands and feet. Therefore, the differences between these two diseases are considerable.

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Written by Li Jie
Orthopedics
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How to treat rheumatoid arthritis?

Rheumatoid arthritis-induced joint pain has several distinct characteristics: The first is that it initially affects the small joints of the limbs, typically involving the hands, feet, wrists, and ankles, before spreading to larger joints. It rarely starts in the large joints first. Secondly, the onset is generally symmetrical, meaning it seldom affects just a single limb or joint. Typically, if the disease manifests, it affects both limbs simultaneously. Another characteristic is significant morning stiffness, meaning a feeling of stiffness upon waking up in the morning. Generally, by combining auxiliary tests such as blood tests and imaging, a clear diagnosis of rheumatoid arthritis can be made. Once diagnosed, it is advised that patients seek treatment at a reputable hospital in the rheumatology and immunology department or orthopedics, targeting specific treatments and avoiding unlicensed practitioners. Common rheumatoid arthritis treatment plans start with medications to alleviate symptoms, using immunosuppressants. In severe cases, a small, short-term dose of steroids may be used. Additionally, symptomatic treatment may include topical applications of ointments to improve blood circulation, reduce swelling, and alleviate pain. Patients can also take non-steroidal anti-inflammatory drugs orally to relieve symptoms. Furthermore, traditional Chinese medicine is also a very effective method, and patients can take specific herbal medicines as symptomatic treatment for rheumatic joint pain, which are also very effective. (Please follow a professional physician's guidance when using medications and do not medicate blindly.)

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Written by Liu Li Ning
Rheumatology
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Rheumatoid arthritis skin manifestations

Rheumatoid arthritis does not have specific skin manifestations. Rheumatoid arthritis is an immune-mediated erosive arthritis, clinically characterized by systemic symmetrical multiple joint swelling and pain, accompanied by morning stiffness, often lasting for more than an hour. Rheumatoid arthritis can affect the proximal interphalangeal joints and middle joints of both hands, as well as both wrists, elbows, shoulders, ankles, knees, and other joints. Some patients may experience involvement of the temporomandibular joint. Rheumatoid arthritis can also have extrarticular manifestations, such as affecting the hematological system, which may result in mild to moderate anemia, or affecting the lungs, which can lead to interstitial pneumonia or pulmonary fibrosis.