How is rheumatoid arthritis treated?

Written by Yang Ya Meng
Rheumatology
Updated on March 07, 2025
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The treatment of rheumatoid arthritis mainly falls into three categories:

The first category includes anti-inflammatory and pain-relief medications, which are further divided into non-steroidal pain-relief drugs and low-dose corticosteroids.

For rheumatoid arthritis, the most crucial treatment involves the choice of the second category: slow-acting drugs. Common drugs used in treating the key aspects of rheumatoid arthritis include immunosuppressants such as methotrexate and leflunomide.

If the patient does not respond well to the above two conventional treatments, a third option that can be considered is treatment with biological agents. Commonly used biological agents include tumor necrosis factor antagonists. Before using biological agents, it is necessary to strictly rule out hepatitis, tuberculosis, and neoplastic diseases.

(Please use medication under the guidance of a doctor)

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Written by Li Jing
Rheumatology
39sec home-news-image

Can rheumatoid arthritis be cured?

Rheumatoid arthritis is a chronic autoimmune disease characterized by systemic damage to multiple joints with an unclear cause. Thus, it cannot be cured, meaning it cannot be completely healed. Treatment can only alleviate joint pain and morning stiffness through medication, delay the onset of complications, reduce bone damage, decrease disability rates, and improve quality of life. This is the comprehensive purpose of treatment. Therefore, early diagnosis and standardized treatment of this disease are essential to prevent joint deformities and to maintain quality of life.

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Written by Li Jing
Rheumatology
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Does rheumatoid arthritis cause fever?

Rheumatoid arthritis is categorized as an autoimmune disease, primarily characterized by swelling and pain in multiple joints, particularly in the wrists or ankles. It also causes morning stiffness, and may be accompanied by fatigue, low fever, muscle soreness, and even weight loss. The onset of the disease is generally gradual for most people, and symptoms can vary significantly from one individual to another. A minority of patients may experience a rapid onset of symptoms, developing joint problems within days or weeks. Therefore, during the acute phase of rheumatoid arthritis, patients may experience a mild or moderate fever. However, it is important to differentiate whether this fever is due to an infection or the activity of the disease itself. This can be determined through regular blood tests, erythrocyte sedimentation rate (ESR), C-reactive protein, and related symptoms.

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Written by Yang Ya Meng
Rheumatology
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Is rheumatoid arthritis serious?

Patients with rheumatoid arthritis, if treated reasonably and formally, can achieve clinical remission, so in this sense, rheumatoid arthritis is not severe. However, if patients do not adhere to formal treatment for a long time, after a long period, they may develop joint deformities and ankylosis, resulting in disability. From this perspective, rheumatoid arthritis should be taken seriously. Commonly used drugs for treating rheumatoid arthritis include anti-inflammatory pain relievers, with non-steroidal pain relievers being the most commonly used, such as sustained-release diclofenac sodium tablets. The most important step in treating rheumatoid arthritis is the selection of immunosuppressants, with common immunosuppressants including methotrexate and leflunomide. (Medication should be used under the guidance of a doctor based on specific circumstances.)

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Written by Li Jing
Rheumatology
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Rheumatoid arthritis symptoms

Rheumatoid arthritis is categorized as an autoimmune disease and is a chronic autoimmune condition that is destructive to joints. It is primarily characterized by symmetric polyarthritis, with clinical manifestations varying significantly among individuals. Most cases begin gradually, initially presenting with symmetrical pain and swelling in the wrists. This often accompanies morning stiffness, fatigue, low-grade fever, muscle pain, or weight loss. In a minority of cases, the onset is more abrupt, with typical clinical manifestations appearing within a few days, including joint dysfunction, morning stiffness, and joint pain and swelling. Joint deformity is a later manifestation of the disease, indicating that the disease was not well-controlled, leading to joint damage.

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Written by Cheng Bin
Orthopedics
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Is joint pain rheumatoid arthritis?

Firstly, it should be noted that there are many causes of joint pain in clinical practice, and it is not necessarily caused by rheumatoid arthritis. Of course, rheumatoid arthritis can also cause joint pain in patients. In addition, there are some other reasons, for example, local joint bacterial infection in patients can also cause joint pain. Furthermore, joint injuries leading to fractures, dislocations, soft tissue damage, ligament injuries, and meniscus injuries can also cause joint pain. Additionally, the presence of osteoarthritis or gouty arthritis can similarly lead to joint pain in patients.