Early symptoms of ankylosing spondylitis

Written by Sun Shu Jian
Orthopedics
Updated on January 13, 2025
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The early symptoms of ankylosing spondylitis mainly include insidious onset of pain and discomfort in the back and hip joints.

The pain is often intermittent and worse at night. Patients frequently wake up at night due to back pain, which can be alleviated by slight movement. Therefore, when patients experience unexplained back and hip joint pain, it is necessary to determine whether ankylosing spondylitis could be a possibility.

In the early stages, a sacroiliac joint CT scan and hematological examination can be performed to confirm the diagnosis. Once diagnosed, prompt standardized treatment is necessary. Generally, this can control synovial inflammation and pain, prevent deformities of the spine and joints, and help patients return to normal life and work.

Other Voices

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Written by Li Jing
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Does ankylosing spondylitis spread by contagion?

Ankylosing spondylitis is a systemic autoimmune disease of unknown cause, primarily affecting the axial joints, mainly involving the sacroiliac joints, and commonly occurring in young and middle-aged males. The symptoms of this disease are severe, progress rapidly, and there is a genetic predisposition, but it is not a contagious disease and does not have infectivity. If a patient with ankylosing spondylitis also contracts another infectious disease, it is because the other disease is infectious, not because ankylosing spondylitis is. It belongs to autoimmune diseases and cannot be cured, but can only be managed with medication to delay the onset of joint deformity.

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Is ankylosing spondylitis serious?

Patients with ankylosing spondylitis, if treated actively in the early stages, the condition is not severe. However, if the patient continues to seek irregular and improper medical care, it is possible to develop severe complications such as kyphosis and spinal ankylosis. In severe cases, patients may even self-harm. Therefore, it is advised that patients with ankylosing spondylitis seek treatment early, before the onset of spinal ankylosis. The treatment plan mainly includes non-steroidal analgesics, such as diclofenac sodium sustained-release tablets, medications to control the condition, such as sulfasalazine tablets, and biologic treatments. With the above treatments, the condition of ankylosing spondylitis can be controlled. (Medication use should be under the guidance of a doctor.)

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Ankylosing Spondylitis Test Items

Ankylosing spondylitis is a systemic disease of unknown cause, primarily characterized by chronic inflammation of the axial joints. It mainly affects the sacroiliac joints and leads to bony ankylosis, predominantly occurring in males, especially young males. The disease has a significant familial genetic tendency. The main symptoms are pain or discomfort in the lower back and back, typically occurring at night, accompanied by difficulty turning over. Stiffness is evident in the morning or after sitting for a long time, but symptoms may alleviate after physical activity. In young and middle-aged males showing these symptoms, ankylosing spondylitis should be suspected first. The main diagnostic methods include blood tests for HLA-B27, and imaging such as CT or MRI of the sacroiliac joints to detect any sacroiliitis. Diagnosis primarily relies on the combination of symptoms, HLA-B27 results, and sacroiliac joint CT findings.

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How long does ankylosing spondylitis take to cause paralysis?

Ankylosing spondylitis is an autoimmune disease and a chronic condition. It primarily involves damage to the axial joints. Additionally, extrajoint manifestations can occur, such as iritis, keratitis, and corneal perforation. Currently, there is no effective cure for ankylosing spondylitis, meaning it cannot be completely cured. The treatment focuses on long-term medication management to control symptoms, delay complications, improve quality of life, and reduce disability rates. This is the main goal of treatment. Without proper treatment, deformities in the joints and spinal ankylosis can develop within a relatively short period, about seven to eight years, leading to a hunched back and significant restriction in joint mobility. Proper treatment can significantly delay joint damage. Regarding whether ankylosing spondylitis can lead to paralysis, it does not cause paralysis but does result in decreased energy and ability for activities such as turning, twisting the head, or bending, which are significantly restricted.

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What to do about ankylosing spondylitis pain?

The methods for treating pain in ankylosing spondylitis primarily include non-steroidal anti-inflammatory drugs, such as sustained-release diclofenac sodium tablets; secondly, biologics can be considered for pain relief, but before using biologics, it is necessary to rigorously rule out diseases such as hepatitis, tuberculosis, and tumors. During the painful periods of ankylosing spondylitis, patients are advised to rest appropriately to alleviate joint inflammation. However, after the pain subsides, it is recommended that patients engage in functional exercises to prevent complications such as further adhesion and stiffening of the spinal joints. (Specific medications should be taken under the guidance of a physician.)