The initial symptoms of ankylosing spondylitis mainly manifest as morning stiffness in the back. Then, there appears to be pain in the back and hip joints. The pain is generally more noticeable at night, and patients often wake up at night due to back pain. Pain can be significantly relieved after light activity. Early ankylosing spondylitis generally does not have characteristic clinical manifestations. A definitive diagnosis requires physical examinations, imaging studies, and blood tests. After confirming the diagnosis, timely and standard treatment is needed. Treatment can control the inflammation and pain of the synovium, prevent the further development of the disease, and prevent deformities of the spine and joints.