What to check for ankylosing spondylitis?

Written by Yang Ya Meng

Rheumatology

Updated on October 22, 2024

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The examination for ankylosing spondylitis mainly includes blood tests. The main components of the blood tests are erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), ANA along with CCP antibodies, and AKA antibodies, and of course, the most crucial test related to the gene - HLA-B27. Imaging exams can include the following: First, an X-ray of the pelvis, or an MRI of the sacroiliac joints. If the disease has been present for a longer time, a CT of the sacroiliac joints can be chosen. If the patient has elevated ESR and CRP, a positive B27, and lesions in the sacroiliac joints, then the diagnosis of ankylosing spondylitis can be confirmed.

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Written by Yang Ya Meng

Rheumatology

52sec

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What is the ESR level in ankylosing spondylitis?

Patients with ankylosing spondylitis, if not well controlled, can exhibit elevated erythrocyte sedimentation rates (ESR). An ESR higher than 20 mm per hour indicates elevation, suggesting poor disease control. At such times, it is necessary to utilize non-steroidal anti-inflammatory drugs (NSAIDs) such as sustained-release diclofenac sodium tablets. Additionally, medications that control the condition should also be used, like sulfasalazine tablets and thalidomide, among others. While biological agents, commonly tumor necrosis factor (TNF) antagonists, offer the best treatment effectiveness, they are also the most expensive. (The use of medications should be conducted under the guidance of a physician.)

home-news-image

Written by Yang Ya Meng

Rheumatology

55sec

home-news-image

What to check for ankylosing spondylitis?

The examination for ankylosing spondylitis mainly includes blood tests. The main components of the blood tests are erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), ANA along with CCP antibodies, and AKA antibodies, and of course, the most crucial test related to the gene - HLA-B27. Imaging exams can include the following: First, an X-ray of the pelvis, or an MRI of the sacroiliac joints. If the disease has been present for a longer time, a CT of the sacroiliac joints can be chosen. If the patient has elevated ESR and CRP, a positive B27, and lesions in the sacroiliac joints, then the diagnosis of ankylosing spondylitis can be confirmed.

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Written by Yang Ya Meng

Rheumatology

55sec

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What to do about ankylosing spondylitis pain?

The methods for treating pain in ankylosing spondylitis primarily include non-steroidal anti-inflammatory drugs, such as sustained-release diclofenac sodium tablets; secondly, biologics can be considered for pain relief, but before using biologics, it is necessary to rigorously rule out diseases such as hepatitis, tuberculosis, and tumors. During the painful periods of ankylosing spondylitis, patients are advised to rest appropriately to alleviate joint inflammation. However, after the pain subsides, it is recommended that patients engage in functional exercises to prevent complications such as further adhesion and stiffening of the spinal joints. (Specific medications should be taken under the guidance of a physician.)

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Written by Yang Ya Meng

Rheumatology

1min 1sec

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How is ankylosing spondylitis treated?

The treatment of ankylosing spondylitis mainly consists of three types: The first is anti-inflammatory pain relief, primarily using non-steroidal pain relief medications, such as sustained-release diclofenac sodium tablets. The second is the selection of disease control medications, mainly involving drugs like sulfasalazine tablets. For ankylosing spondylitis, the most effective and economically expensive treatment is biological agents therapy. We commonly use drugs such as tumor necrosis factor antagonists. Patients with ankylosing spondylitis during acute pain periods are advised not to engage in intense exercise. However, during remission periods, appropriate functional exercises are recommended to prevent the adhesion and stiffness of spinal joints.

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Written by Yang Ya Meng

Rheumatology

1min 7sec

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How is ankylosing spondylitis treated?

The treatment of ankylosing spondylitis mainly consists of three parts: The first part is anti-inflammatory and pain relief. For anti-inflammatory pain relief, non-steroidal pain relief medications are commonly chosen, such as slow-release diclofenac sodium tablets and celecoxib capsules. The second part involves the selection of medications to control the disease. Common drugs used to control the condition include sulfasalazine, thalidomide, and methotrexate tablets. The third part includes the most effective, yet most expensive, treatment option: biological agents. Common biological agents used are tumor necrosis factor antagonists. However, before using biological agents, strict screening for diseases such as hepatitis, tuberculosis, and cancer is required. Only after excluding these conditions can the treatment with biological agents be considered.