Hypoglycemia poses the greatest harm to the body by damaging brain tissue. If the drop in blood sugar is severe and prolonged, it can cause brain dysfunction due to glucose deprivation in brain tissues. This mainly manifests as changes in the patient's consciousness and personality, and can present as weakness, fatigue, and cognitive impairment. In severe cases, it can lead to seizures or coma. Additionally, degeneration and necrosis can occur in the neurons of the central nervous system within the brain cells, along with cerebral edema, diffuse cerebral hemorrhage, or periodic demyelination. If severe and persistent hypoglycemia is not effectively corrected, it can lead to permanent brain function impairment or death.