Stage IA endometrial cancer

Written by Li Lin

Obstetrics and Gynecology

Updated on September 14, 2024

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Endometrial cancer is a group of epithelial malignant tumors that occur in the endometrium. Clinically, the surgical pathology staging revised by the World Health Organization in 2000 is mainly used, based on the severity of the lesion after surgery. Endometrial cancer can be divided into four stages, where, depending on the size and severity of the lesion, it can further be classified into sub-stages a, b, and c. Stage IA refers to cancer limited to the endometrium and is the earliest stage of endometrial cancer. Stage IA endometrial cancer can be completely cured with surgical treatment.

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Stage IB endometrial cancer treatment

Endometrial carcinoma Stage IB refers to tumors localized to the body of the uterus, where tumor infiltration is less than half of the myometrium. Surgical treatment is feasible for this stage and involves a slightly extensive total hysterectomy coupled with bilateral adnexectomy. During the surgery, a frozen section pathology test should be conducted. If the pathology report from the frozen section indicates special types of endometrial-like cancer, including papillary serous adenocarcinoma, clear cell carcinoma, squamous cell carcinoma, carcinosarcoma, and undifferentiated carcinoma, additional procedures are required. Moreover, if enlarged para-aortic or common iliac lymph nodes are palpated during the surgery, lymphadenectomy of the pelvic and para-aortic lymph nodes should be performed.

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Is surgery necessary for endometrial cancer?

For endometrial cancer, surgery is generally recommended as the first choice, because early-stage endometrial cancer can largely be cured through surgical treatment. Besides surgery, other options include medication, radiation therapy, and chemotherapy, which are used for mid to late stages or in conjunction with surgery in early stages. When treating endometrial cancer, the treatment method should be chosen based on the specific condition and stage of the patient. In early-stage endometrial cancer, surgery is the preferred treatment. Therefore, aside from surgical treatment, patients should choose medication, radiation therapy, or chemotherapy based on their specific conditions.

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Written by Li Lin

Obstetrics and Gynecology

43sec

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Are uterine cancer and endometrial cancer the same?

Uterine cancer is divided into cervical cancer and endometrial cancer. Cervical cancer is a malignant tumor that occurs in the epithelium and glandular tissue of the cervix, while endometrial cancer is a group of epithelial malignant tumors that occur in the endometrium. The two types of cancer differ due to their different sites of origin. Accordingly, the examination and treatment methods adopted are also not completely the same based on the different sites of origin. However, both cervical and endometrial cancers are primarily treated with surgery, followed by corresponding radiotherapy and chemotherapy.

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Written by Shen Li Wen

Obstetrics and Gynecology

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Is surgery necessary for endometrial cancer?

When a woman suffers from endometrial cancer, the primary treatment method is surgery, but there are some special circumstances. For example, if the lesion in the woman is relatively minor, it is atypical hyperplasia, which is a precancerous condition, or it is in the late stage of the disease, or in cases of recurrent endometrial cancer. At this time, treatment can be administered using progestogen drugs, applying high-dose long-term oral intake of effective progestogens, which can suppress the cancerous transformation of the endometrial lining and inhibit the further proliferation of cancer cells. Generally, it involves continuous oral administration for 12 weeks, which is three months, followed by a diagnostic curettage to evaluate the therapeutic effects of the drug. In addition, radiation therapy can also be considered.

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Written by Li Shun Hua

Obstetrics and Gynecology

55sec

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Is endometrial hyperplasia cancer?

Endometrial hyperplasia is not the same as endometrial cancer; it can be treated promptly. Endometrial cancer develops from ongoing endometrial hyperplasia, which can progress into atypical hyperplasia, a precancerous condition of the endometrium. Further development can lead to endometrial cancer. Therefore, it is crucial to treat endometrial hyperplasia actively to prevent its progression to endometrial cancer. Endometrial hyperplasia results from a lack of progesterone influence, causing the endometrium to remain in a proliferative state rather than transitioning to the secretory phase. With the influence of progesterone, the endometrium would not undergo hyperplasia; therefore, treating endometrial hyperplasia with progesterone is advisable.