What to do about endometrial cancer pain?

Written by Liu Jian Wei
Obstetrics and Gynecology
Updated on September 24, 2024
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Endometrial cancer, when cancerous tissues invade local nerves, can cause patients to experience pain. This type of pain is recommended to be alleviated by oral painkillers. Pain caused by cancer is an important factor affecting the quality of life of patients in the middle and late stages of the disease; therefore, in clinical practice, analgesic medications can be administered to relieve symptoms in patients with cancer pain. (Please take medications under the guidance of a doctor.)

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Is surgery necessary for endometrial cancer?

For endometrial cancer, surgery is generally recommended as the first choice, because early-stage endometrial cancer can largely be cured through surgical treatment. Besides surgery, other options include medication, radiation therapy, and chemotherapy, which are used for mid to late stages or in conjunction with surgery in early stages. When treating endometrial cancer, the treatment method should be chosen based on the specific condition and stage of the patient. In early-stage endometrial cancer, surgery is the preferred treatment. Therefore, aside from surgical treatment, patients should choose medication, radiation therapy, or chemotherapy based on their specific conditions.

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How is endometrial cancer diagnosed?

If it concerns endometrial cancer, postmenopausal vaginal bleeding and menstrual disorders during the menopausal transition should prompt an exclusion of endometrial cancer. The most common and valuable method for diagnosing endometrial cancer is through pathological examination results, especially via fractional curettage. The advantage of fractional curettage is that it can differentiate between endometrial cancer and cervical adenocarcinoma, and it can clarify whether the cervical canal is involved, providing a basis for formulating treatment plans. In addition, endometrial cancer can also be assessed using a B-mode ultrasound, but this is only used to provide reference values for clinical diagnosis and management. Another method is hysteroscopy, which allows direct observation of the uterine cavity and cervical canal for any lesions, and tissue can also be collected for biopsy, which is also a very good method.

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Written by Yan Chun
Oncology
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What are the symptoms of endometrial cancer?

Patients with endometrial cancer mainly experience symptoms in three areas: First, obvious symptoms caused by local tumors in the uterus, such as irregular vaginal bleeding, changes in the menstrual cycle, a sense of fullness and dull pain in the lower abdomen and pelvic area, along with significant discomfort and pain. Second, clinical symptoms caused by metastatic lesions. Endometrial cancer can spread through three pathways, which after dissemination can cause a variety of symptoms, such as abdominal pain, bloating, constipation, headache, vomiting, movement disorders, chest tightness, coughing, wheezing, and difficulty breathing. Some patients may also experience bone pain. Third, systemic symptoms, which are typically seen in advanced stages of endometrial cancer and commonly include cachexia, fever, and others.

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Written by Zhang Lu
Obstetrics
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How many times for endometrial cancer chemotherapy?

Post-surgical treatment for endometrial cancer often requires adjunct therapies, commonly including chemotherapy and radiotherapy. The frequency of chemotherapy primarily depends on whether the pathological results of the endometrial cancer reveal high-risk factors. If no high-risk factors are present, regular observation and follow-ups are generally advised. However, if high-risk factors are present, such as lymph node metastasis or local infiltration, this condition requires 4-6 cycles of chemotherapy after surgery, supplemented by radiotherapy. Thus, for endometrial cancer, if high-risk factors exist, chemotherapy is needed for 4-6 cycles; if no high-risk factors are present, chemotherapy is generally unnecessary, and regular follow-ups suffice.

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Written by Xu Xiao Ming
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Causes of Endometrial Cancer

Patients with endometrial cancer generally have factors such as hypertension, diabetes, and obesity that induce the condition. They are more prone to developing endometrial cancer. Furthermore, endometrial cancer is divided into hormone-dependent and non-hormone-dependent types. Hormone-dependent endometrial cancer occurs when there is an excess of estrogen produced in the body without sufficient counteraction by progesterone, leading to excessive growth and proliferation of the endometrial lining. When this growth becomes uncontrolled, it can lead to cancer. Non-hormone-dependent endometrial cancer is not caused by hormonal factors and its development is more complex. Additionally, the pathology type of non-hormone-dependent endometrial cancer is also quite unique.