Does endometrial cancer require chemotherapy?

Written by Xu Xiao Ming
Obstetrics and Gynecology
Updated on April 20, 2025
00:00
00:00

Whether chemotherapy is needed for endometrial cancer depends on its clinical stage. If it is advanced endometrial cancer, such as stage IV, chemotherapy is necessary for these patients. Recurrent endometrial cancer also requires chemotherapy. In the case of early-stage endometrial cancer, surgery can be used. The purpose of the surgery is to stage the pathology of the cancer to determine the extent of endometrial cancer infiltration. After the surgery, it will be assessed whether chemotherapy is needed. Therefore, whether chemotherapy is needed for endometrial cancer depends on the surgical staging. Some endometrial cancers may require not only chemotherapy but also radiotherapy treatment.

Other Voices

doctor image
home-news-image
Written by Liu Jian Wei
Obstetrics and Gynecology
39sec home-news-image

How is endometrial cancer diagnosed?

In the clinical setting, when endometrial cancer is suspected, further pathological examination is required. Generally, endometrial tissue can be obtained through fractional curettage or hysteroscopic endometrial biopsy. The acquired endometrium is then subject to a pathological examination, observing the morphology of the endometrial cells under a microscope. If cancer cells are detected, a diagnosis of endometrial cancer can be made. Therefore, the confirmation of endometrial cancer in clinical practice must be based on pathological examination.

doctor image
home-news-image
Written by Liu Jian Wei
Obstetrics and Gynecology
30sec home-news-image

What to do about endometrial cancer pain?

Endometrial cancer, when cancerous tissues invade local nerves, can cause patients to experience pain. This type of pain is recommended to be alleviated by oral painkillers. Pain caused by cancer is an important factor affecting the quality of life of patients in the middle and late stages of the disease; therefore, in clinical practice, analgesic medications can be administered to relieve symptoms in patients with cancer pain. (Please take medications under the guidance of a doctor.)

doctor image
home-news-image
Written by Xu Xiao Ming
Obstetrics and Gynecology
53sec home-news-image

Stage IB endometrial cancer treatment

Endometrial carcinoma Stage IB refers to tumors localized to the body of the uterus, where tumor infiltration is less than half of the myometrium. Surgical treatment is feasible for this stage and involves a slightly extensive total hysterectomy coupled with bilateral adnexectomy. During the surgery, a frozen section pathology test should be conducted. If the pathology report from the frozen section indicates special types of endometrial-like cancer, including papillary serous adenocarcinoma, clear cell carcinoma, squamous cell carcinoma, carcinosarcoma, and undifferentiated carcinoma, additional procedures are required. Moreover, if enlarged para-aortic or common iliac lymph nodes are palpated during the surgery, lymphadenectomy of the pelvic and para-aortic lymph nodes should be performed.

doctor image
home-news-image
Written by Li Li Jie
Obstetrics and Gynecology
1min 12sec home-news-image

Is endometrial tofu dregs-like a sign of endometrial cancer?

Endometrial cancer usually manifests in five main aspects. First, irregular vaginal bleeding, which is typically light but can be moderate in some patients. If the patient is postmenopausal, the bleeding often appears as either continuous or intermittent. Second, menstrual disorders, which are a common symptom of endometrial cancer as it is a malignant tumor occurring in the endometrium and significantly affects menstruation. Third, vaginal discharge, where some patients may experience a discharge of thin, white secretions, or a very small amount of bloody discharge in the early stages of the disease. Fourth, pain; once a patient develops endometrial cancer, the tumor may cause bleeding and possibly lead to infection. Fifth, abdominal masses, which can occur if there is a combination of large uterine fibroids or in advanced stages, potentially leading to the formation of large masses in the pelvic cavity due to the spread of a uterine cavity abscess.

doctor image
home-news-image
Written by Tang Mei Xiang
Obstetrics and Gynecology
1min 25sec home-news-image

How is endometrial cancer diagnosed?

Endometrial cancer often manifests as vaginal bleeding after menopause, and in women who have not experienced menopause, it often presents as menstrual irregularities. The diagnostic methods for endometrial cancer include the following: 1. Fractional curettage is the most important method for diagnosing endometrial cancer. First, scrape the cervical canal, then sequentially scrape the endometrial tissue from each part of the uterine body, label the specimens separately, and send them for pathological examination together. 2. Cytological examination is a method for screening for endometrial cancer. A specially made uterine cavity suction tube or brush is inserted into the uterine cavity to collect secretions for cytological culture. 3. Hysteroscopic examination allows direct observation of the growth of endometrial lesions and can also obtain live tissue for pathological examination. It involves pelvic ultrasound examination to understand the size of the lesion, surrounding infiltration, etc. 5. Other methods, such as lymphangiography, CT, MRI, and serum CA125 testing.