How is endometrial cancer diagnosed?

Written by Tang Mei Xiang
Obstetrics and Gynecology
Updated on September 13, 2024
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Endometrial cancer often manifests as vaginal bleeding after menopause, and in women who have not experienced menopause, it often presents as menstrual irregularities. The diagnostic methods for endometrial cancer include the following: 1. Fractional curettage is the most important method for diagnosing endometrial cancer. First, scrape the cervical canal, then sequentially scrape the endometrial tissue from each part of the uterine body, label the specimens separately, and send them for pathological examination together. 2. Cytological examination is a method for screening for endometrial cancer. A specially made uterine cavity suction tube or brush is inserted into the uterine cavity to collect secretions for cytological culture. 3. Hysteroscopic examination allows direct observation of the growth of endometrial lesions and can also obtain live tissue for pathological examination. It involves pelvic ultrasound examination to understand the size of the lesion, surrounding infiltration, etc. 5. Other methods, such as lymphangiography, CT, MRI, and serum CA125 testing.

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Written by Zhang Xiu Rong
Obstetrics and Gynecology
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Is a thick endometrium the same as cancer?

Endometrial thickening is not necessarily cancerous. Causes of endometrial thickening generally include irregular hyperplasia or endometrial polyps, both of which can lead to thickening of the endometrium, but this is not necessarily indicative of cancer. Whether it is endometrial cancer is usually determined if patients with endometrial thickening do not show clear improvement after treatment with medication. Typically, a curettage procedure is performed to collect tissue for pathological examination. If the pathology report indicates endometrial cancer or precancerous lesions, then it will be reported. Therefore, endometrial thickening is not necessarily indicative of endometrial cancer, and it can occur with conditions like endometrial polyps or irregular endometrial hyperplasia. Treatment at this stage should be based on the pathological results. Thus, while endometrial thickening should be taken seriously, it is not necessarily cancerous.

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Written by Xu Xiao Ming
Obstetrics and Gynecology
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Does endometrial cancer require chemotherapy?

Whether chemotherapy is needed for endometrial cancer depends on its clinical stage. If it is advanced endometrial cancer, such as stage IV, chemotherapy is necessary for these patients. Recurrent endometrial cancer also requires chemotherapy. In the case of early-stage endometrial cancer, surgery can be used. The purpose of the surgery is to stage the pathology of the cancer to determine the extent of endometrial cancer infiltration. After the surgery, it will be assessed whether chemotherapy is needed. Therefore, whether chemotherapy is needed for endometrial cancer depends on the surgical staging. Some endometrial cancers may require not only chemotherapy but also radiotherapy treatment.

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Written by Zhang Xiu Rong
Obstetrics and Gynecology
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Endometrial cancer B-ultrasound manifestations

Normally, the endometrium has a certain thickness. Patients with endometrial cancer usually show thickening of the endometrium, accompanied by irregular bleeding and abdominal pain. In severe cases, patients may experience excessive discharge from the half-vagina, accompanied by a fishy and foul odor. Typically, in cases of endometrial cancer, an ultrasound can reveal thickening of the endometrium and abnormal endometrial echoes, and some patients may show significant blood flow signals around the area according to reports. These signs generally suggest a high likelihood of endometrial cancer. The diagnosis of endometrial cancer typically involves undergoing a diagnostic curettage at the hospital. The tissue scrapped during this procedure is sent for pathology. Afterward, based on the pathology results, the type and nature of the endometrial cancer are determined. Therefore, the presence of endometrial cancer can generally be inferred from an ultrasound as well.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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How is endometrial cancer diagnosed?

In the clinical setting, when endometrial cancer is suspected, further pathological examination is required. Generally, endometrial tissue can be obtained through fractional curettage or hysteroscopic endometrial biopsy. The acquired endometrium is then subject to a pathological examination, observing the morphology of the endometrial cells under a microscope. If cancer cells are detected, a diagnosis of endometrial cancer can be made. Therefore, the confirmation of endometrial cancer in clinical practice must be based on pathological examination.

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Written by Li Lin
Obstetrics and Gynecology
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Are uterine cancer and endometrial cancer the same?

Uterine cancer is divided into cervical cancer and endometrial cancer. Cervical cancer is a malignant tumor that occurs in the epithelium and glandular tissue of the cervix, while endometrial cancer is a group of epithelial malignant tumors that occur in the endometrium. The two types of cancer differ due to their different sites of origin. Accordingly, the examination and treatment methods adopted are also not completely the same based on the different sites of origin. However, both cervical and endometrial cancers are primarily treated with surgery, followed by corresponding radiotherapy and chemotherapy.