Why does hyperkalemia cause muscle weakness?
The muscles that govern movement in our body are striated muscles, and each muscle cell in striated muscles has many receptors, which we can think of as a signal receiving and transmitting station. When we need to move, the brain nerves will send a signal to this station, which then controls muscle movement. A very important ion in muscle movement is the calcium ion. There is a receptor for calcium ions on our muscle cells, and it is related to the concentration of blood potassium. When the concentration of blood potassium is too low, a condition known as hypokalemia, or too high, known as hyperkalemia, the calcium ion receptor will be inhibited. At this point, our muscles will exhibit symptoms of muscle weakness.
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